Anti-<i>Chlamydia trachomatis</i> Host Defence Arsenal Within the Cervicovaginal Environment. [PDF]
Filardo S +3 more
europepmc +1 more source
NR4A1 Exerts Pro‐Tumor Role in Glioblastoma via Inducing xCT/GPX4‐Regulated Ferroptosis
ABSTRACT Purpose This study investigates NR4A1's paradoxical roles in glioblastoma (GBM) progression, focusing on its mechanistic link to ferroptosis regulation. We aimed to resolve conflicting reports of NR4A1 as both an oncogene and a tumor suppressor by defining its transcriptional control over xCT/GPX4‐mediated iron homeostasis and its clinical ...
Peng Tao +10 more
wiley +1 more source
Decoy Receptors in Autoimmunity: Molecular Guardians and Pathogenic Players in Immune Dysregulation. [PDF]
Farahani H +4 more
europepmc +1 more source
SNUPN‐Related Muscular Dystrophy: Novel Phenotypic, Pathological and Functional Protein Insights
ABSTRACT Objective SNUPN‐related muscular dystrophy or LGMDR29 is a new entity that covers from a congenital or childhood onset pure muscular dystrophy to more complex phenotypes combining neurodevelopmental features, cataracts, or spinocerebellar ataxia. So far, 12 different variants have been described.
Nuria Muelas +18 more
wiley +1 more source
Natural killer cell exhaustion in ovarian cancer: from molecular suppression to therapeutic revival. [PDF]
Ning J, Yao L.
europepmc +1 more source
Rapid and reversible disappearance of beta‐adrenergic cell surface receptors.
M. Staehelin, P. Simons
semanticscholar +1 more source
Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen +18 more
wiley +1 more source
Decoding missense variants pleiotropy in the immune GPCR P2RY8. [PDF]
Shen S, Luo R, Shao Z.
europepmc +1 more source
Effect of mutations in the PCSK9 gene on the cell surface LDL receptors.
J. Cameron +5 more
semanticscholar +1 more source

