Results 161 to 170 of about 80,433 (248)

Progress in cell-based immunotherapies for solid tumors. [PDF]

Discov Oncol
Zhang L, Zhang D, Wang B.
europepmc   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source

Anti-CD19 chimeric antigen receptor T cells in Evans syndrome of systemic lupus erythematosus. [PDF]

Ann Hematol
Lang M, Peng L, Jiang N, Li M, Zhang Y, Zeng X, Zhou D.   +6 more
europepmc   +1 more source

Imaging the Tumor Microenvironment Beyond Anatomy: Functional, Immune, Stromal, and Metabolic Signatures for Precision Oncology

iRADIOLOGY, EarlyView.
This article highlights the importance of imaging the tumor microenvironment (TME) beyond conventional anatomy‐based approaches to enable more precise oncology. It focuses on capturing key biological dimensions of tumors—vascular function and hypoxia, immune response, stromal remodeling, and metabolic activity—using advanced imaging techniques.
Karthikeyan Elumalai, Gayathri Krishnakumar   +1 more
wiley   +1 more source

The Regulatory Role and Mechanism of Myoferlin in Mitophagy During Papillary Thyroid Carcinogenesis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Papillary thyroid carcinoma (PTC) is the most prevalent subtype of thyroid cancer; however, the regulatory mechanisms by which mitophagy influences its progression remain inadequately elucidated. This study sought to examine the role of myoferlin (MYOF) in mitophagy and its molecular basis during PTC development. Utilizing three paired PTC and
Wen‐Chao Lyu, Yang‐Shuai Wang, Chun‐Yang Shang, Ming Qi, Tong‐Chang Li, Li‐Xin Lian, Hai‐Quan Qiao   +6 more
wiley   +1 more source

From CAR-T to CAAR-T: redefining targeting strategies in B-cell malignancies through idiotype-directed cellular therapy. [PDF]

Front Immunol
Buczek T, Butrym A.
europepmc   +1 more source

Highlights in IO: next-generation CAR-T therapy for glioblastoma. [PDF]

J Immunother Cancer
Yamaguchi J, Okada H.
europepmc   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Sweet-like syndrome secondary to chimeric antigen receptor T-cell therapy for multiple myeloma: a case report. [PDF]

Front Immunol
Ouyang X, Huang Y, Huang Y, Yi S, Wang Y, Fang L.   +5 more
europepmc   +1 more source

Divergent strigolactones or karrikins signaling is mediated by preferred AtD14/KAI2-MAX2-SMXL complex targeting specific SMXL domains. [PDF]

iScience
Xie M, Xu X, Zhang M, Chen H, Chen L, Yao R.   +5 more
europepmc   +1 more source