Results 181 to 190 of about 30,055 (235)

Pyloric Cholecystokinin Receptors

1991
Central or peripheral administration of the brain gut peptide cholecystokinin (CCK) results in a range of biological actions. CCK binding sites at which these actions may be mediated have been identified in multiple brain regions and at various sites in the gastrointestinal tract.
T. H. Moran, L. Shnayder, G. J. Schwartz, P. R. McHugh   +3 more
openaire   +1 more source

Role of cholecystokinin-A and cholecystokinin-B receptors in anxiety

Amino Acids, 2002
Evidence from several laboratories indicates that the anxiogenic effects of cholecystokinin (CCK) are mediated by CCKB receptors. However, it has been reported that CCKA receptors have been found in brain and CCKA antagonists have anxiolytic properties.
A M, Hernandez-Gómez, R, Aguilar-Roblero, M, Pérez de la Mora   +2 more
openaire   +2 more sources

Cholecystokinin (CCK) Receptor Antagonists

Current Pharmaceutical Design, 1995
Receptor antagonists of the endogenous peptide CCK have potential therapeutic utility for the treatment of a number of gastrointestinal and central nervous system disorders. This article reviews recent developments in the general area of CCK receptor/ligand research.
R. M. Freidinger, M. G. Bock, S. B. Freedman, V. G. Matassa   +3 more
openaire   +1 more source

Cholecystokinin receptor subtypes and neuromodulation

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 1989
The sulfated octapeptide of cholecystokinin (CCK-8S) and CCK fragments have been administered to mice to determine the subtype and location of the CCK receptor that modulates the release of dopamine (DA) in brain. 1. Centrally (i.c.v.) or peripherally (s.c.) administered CCK-8S lowers DA release, and to a lesser extent, metabolism, in the neostriatum ...
openaire   +2 more sources

Immunolocalisation of cholecystokinin receptors

2022
This thesis was scanned from the print manuscript for digital preservation and is copyright the author. Researchers can access this thesis by asking their local university, institution or public library to make a request on their behalf. Monash staff and postgraduate students can use the link in the References field.
openaire   +1 more source

The cholecystokinin receptor antagonist CR1409 increases plasma cholecystokinin in rats

Regulatory Peptides, 1989
This study was undertaken to determine whether plasma cholecystokinin (CCK) levels are affected by the administration of the CCK-receptor antagonist CR1409 to rats. Infusion of 0.19, 0.94 and 4.75 mg/kg.h CR1409 for 30 min each into 6 conscious rats increased (P less than 0.05) plasma CCK from 1.3 +/- 0.5 to 6.0 +/- 1.2, 5.4 +/- 1.2, and 5.4 +/- 1.0 pM,
J B, Jansen, A J, de Jong, C B, Lamers
openaire   +2 more sources

[Cholecystokinin and cholecystokinin receptor].

Nihon rinsho. Japanese journal of clinical medicine, 1996
Cholecystokinin (CCK) act as hormones and neuropeptides on central and peripheral CCK receptors. The application of modern molecular biological techniques has identified two CCK receptors, CCK-A receptor (CCKAR) and CCK-B/gastrin receptor (CCKBR). The genes of CCKAR and CCKBR consist of five exons interrupted by four introns.
openaire   +1 more source

Proglumide analogues: potent cholecystokinin receptor antagonists

American Journal of Physiology-Gastrointestinal and Liver Physiology, 1985
Proglumide [N-(benzoyl)-L-glutamic acid-1-di-n-propylamide] is a specific cholecystokinin receptor antagonist. In the present study we synthesized various analogues of proglumide and used pancreatic acini from guinea pig pancreas to examine the abilities of these analogues to function as cholecystokinin receptor antagonists.
R T, Jensen, R B, Murphy, M, Trampota, L H, Schneider, S W, Jones, J M, Howard, J D, Gardner   +6 more
openaire   +2 more sources

Cholecystokinin and cholecystokinin receptors

Journal of Gastroenterology, 2003
Kyoko, Miyasaka, Akihiro, Funakoshi
openaire   +2 more sources

Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder

2004
Panic disorder like other neuropsychiatric disorders is believed to be caused by multiple psychosocial and biological factors. Several lines of evidence point to a role for the peptide neurotransmitter cholecystokinin in the pathogenesis of panic disorder.
V G, Hösing, A, Schirmacher, G, Kuhlenbäumer, C, Freitag, P, Sand, C, Schlesiger, C, Jacob, J, Fritze, P, Franke, M, Rietschel, H, Garritsen, M M, Nöthen, R, Fimmers, F, Stögbauer, J, Deckert   +14 more
openaire   +2 more sources