Further Insights Into Anticholinergic Action Informed by Japanese Anticholinergic Risk Scale. [PDF]
Mogi M +4 more
europepmc +1 more source
Sentience in cephalopod molluscs: an updated assessment
ABSTRACT This article evaluates the evidence for sentience – the capacity to have feelings – in cephalopod molluscs: octopus, cuttlefish, squid, and nautilus. Our framework includes eight criteria, covering both whether the animal's nervous system could support sentience and whether their behaviour indicates sentience.
Alexandra K. Schnell +4 more
wiley +1 more source
Impact of distinct neurotransmitter release modes on neuronal signaling. [PDF]
Zhang KJ, Monteggia LM, Kavalali ET.
europepmc +1 more source
Navigating the Genetic Risk of Chemotherapy‐Induced Hearing Loss in the Stria Vascularis
Cisplatin is a chemotherapy drug that causes permanent hearing loss by damaging a critical tissue lining the inner ear, called the stria vascularis (SV). Currently, the molecular mechanisms of SV damage are largely unknown and the incidence of ototoxicity in patients cannot be reliably predicted.
Tara Lazetic +4 more
wiley +1 more source
The influence of dopamine receptor SNPs on substance use disorder in a Jordanian cohort. [PDF]
Al-Sanabra O, Al-Eitan L, Alasmar M.
europepmc +1 more source
Limited evidence exists synthesizing the risk of acute kidney injury (AKI) associated with the concomitant administration of multiple nephrotoxic drugs, and even less examining the concept of nephrotoxic burden. The objective of this scoping review was to (1) identify definitions of nephrotoxic burden; (2) methods used to quantify (use of calculations)
Wafa Alatawi +6 more
wiley +1 more source
The role of nucleus accumbens dopamine signaling in the development of morphine tolerance in neuropathic pain. [PDF]
Cui S +6 more
europepmc +1 more source
Pharmacogenomics of Major Depressive Disorder in Indigenous Amazonian Populations
Major depressive disorder is a highly prevalent psychological disorder worldwide and its main treatment is the use of Selective Serotonin Reuptake Inhibitors. However, few studies have demonstrated the relationship between the presence of genetic variants in pharmacogenes and the efficacy of these drugs, especially in populations with a unique genetic ...
Kaio Evandro Cardoso Aguiar +9 more
wiley +1 more source
Structural Basis for D3/D4-Selective Antagonism of Piperazinylalkyl Pyrazole/Isoxazole Analogs. [PDF]
Choi KE +6 more
europepmc +1 more source
Learning Strategies from Nature's Blueprint to Cyclic Carbonate Synthesis
The development of sustainable synthetic methods for cyclic carbonates draws inspiration from nature, focusing on eco‐friendly processes and renewable resources like CO2 and biomass. This review explore various CO2 activation mechanisms, green chemistry principles, and green catalysts.
Erika Saccullo +4 more
wiley +1 more source

