Results 221 to 230 of about 2,499,152 (288)

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

Manganese Neurotoxicity and Familial Disorders of Manganese Transport

open access: yesAnnals of the Child Neurology Society, EarlyView.
ABSTRACT Manganese is the 12th most common element in the Earth's crust and is an essential industrial component. Biologically, this metal plays an important role as a constituent of numerous enzymes. While manganese is required for normal biochemical and physiological processes, manganese excess can lead to significant toxicity, particularly to the ...
Sidney M. Gospe Jr.
wiley   +1 more source

Striatal dopamine tone is positively associated with adiposity in humans as determined by PET using dual dopamine type-2 receptor antagonist tracers. [PDF]

open access: yesMol Psychiatry
Darcey VL   +18 more
europepmc   +1 more source

About Sugar Addiction. [PDF]

open access: yesBrain Behav
Qin D, Qi J, Shi F, Guo Z, Li H.
europepmc   +1 more source

Striatal dopamine can enhance both fast working memory, and slow reinforcement learning, while reducing implicit effort cost sensitivity. [PDF]

open access: yesNat Commun
Westbrook A   +7 more
europepmc   +1 more source

EC<sub>50</sub> images reveal reproducible spatial variation in drug affinity across single- and repeat-dose occupancy studies. [PDF]

open access: yesJ Cereb Blood Flow Metab
Ibrahimy A   +11 more
europepmc   +1 more source
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Multiple receptors for dopamine

Nature, 1979
Pharmacological and biochemical criteria can be used to separate those dopamine receptors which are linked to the enzyme adenylyl cyclase and those which are not.
J. Kebabian, D. Calne
semanticscholar   +4 more sources

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