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Electrochemical Science Advances, EarlyView.ABSTRACT Cancer is a result of uncontrolled cell growth with the potential to damage or spread to another part of the body. It is the deadliest disease in the world; therefore, rapid and sensitive detection is essential to fight it. In the past few decades, many diagnosis tools have been developed to detect cancer and monitor therapy progress.
Md Mobarok Karim, Tahera Lasker
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Exploring biomarkers of neurodegeneration in epilepsy: Critical insights
Epileptic Disorders, EarlyView.Abstract The advent of biofluid biomarkers for neurodegenerative disorders has precipitated a surge in recent evidence regarding their role in epilepsy. In this literature review, we examine the diagnostic, prognostic, and therapeutic potential of several biomarkers, including amyloid‐beta (Aβ) protein, total (t‐tau), phosphorylated tau (p‐tau) protein,
Rida Farhan +7 more
wiley +1 more source
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Multiple receptors for dopamine
Nature, 1979Pharmacological and biochemical criteria can be used to separate those dopamine receptors which are linked to the enzyme adenylyl cyclase and those which are not.
John W. Kebabian, Donald B. Calne
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Dopamine receptors: from structure to function.
Physiological Reviews, 1998The diverse physiological actions of dopamine are mediated by at least five distinct G protein-coupled receptor subtypes. Two D1-like receptor subtypes (D1 and D5) couple to the G protein Gs and activate adenylyl cyclase.
C. Missale +4 more
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Dopamine receptor pharmacology
Trends in Pharmacological Sciences, 1994Although antipsychotic drugs originally helped to discover dopamine receptors, the five dopamine receptors presently identified and cloned are facilitating the search for and discovery of more selective antipsychotic and antiparkinson drugs. The D1-like dopamine receptors, D1 and D5, are sensitive to the same drugs as the D1 receptor in native tissues,
Philip Seeman, Hubert H.M. Van Tol
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A Comparison of the Vascular Dopamine Receptor with Other Dopamine Receptors
Annual Review of Pharmacology and Toxicology, 1978The dopamine (DA) receptor has had an interesting history. Unusual actions were attributed to the catecholamine for many years, but these effects were generally considered to be manifestations of activation of 0.and ,8-adrenergic receptors rather thap results of action of DA on a specific receptor (1). The pendulum now has swung the other way.
P H Volkman, J D Kohli, L I Goldberg
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Cocaine receptors on dopamine transporters are related to self-administration of cocaine.
Science, 1987Although cocaine binds to several sites in the brain, the biochemical receptor mechanism or mechanisms associated with its dependence producing properties are unknown.
M. C. Ritz +3 more
semanticscholar +1 more source
2012
Publisher Summary This chapter focuses on the role of dopamine receptors in neurotransmission, their structures, and their functions. Dopamine (DA) is one of the major monoamine neurotransmitters in the mammalian brain. It is generated by hydroxylation and decarboxylation of the amino acid tyrosine, and further metabolized into epinephrine and ...
Nikhil M. Urs +2 more
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Publisher Summary This chapter focuses on the role of dopamine receptors in neurotransmission, their structures, and their functions. Dopamine (DA) is one of the major monoamine neurotransmitters in the mammalian brain. It is generated by hydroxylation and decarboxylation of the amino acid tyrosine, and further metabolized into epinephrine and ...
Nikhil M. Urs +2 more
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Dopamine Receptor and Hypertension
Current Medicinal Chemistry-Cardiovascular & Hematological Agents, 2005Dopamine plays an important role in the pathogenesis of hypertension by regulating epithelial sodium transport and reactive oxygen and by interacting with vasopressin, renin-angiotensin, and the sympathetic nervous system. Decreased renal dopamine production and/or impaired dopamine receptor function have been reported in hypertension.
Pedro A. Jose +3 more
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Dopamine Receptors And Hypertension
Acta Clinica Belgica, 1988Dopamine receptors and ...
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