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Multiple receptors for dopamine
Nature, 1979Pharmacological and biochemical criteria can be used to separate those dopamine receptors which are linked to the enzyme adenylyl cyclase and those which are not.
J. Kebabian, D. Calne
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Dopamine receptor pharmacology
Trends in Pharmacological Sciences, 1994Although antipsychotic drugs originally helped to discover dopamine receptors, the five dopamine receptors presently identified and cloned are facilitating the search for and discovery of more selective antipsychotic and antiparkinson drugs. The D1-like dopamine receptors, D1 and D5, are sensitive to the same drugs as the D1 receptor in native tissues,
Philip Seeman, Hubert H.M. Van Tol
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A Comparison of the Vascular Dopamine Receptor with Other Dopamine Receptors
Annual Review of Pharmacology and Toxicology, 1978The dopamine (DA) receptor has had an interesting history. Unusual actions were attributed to the catecholamine for many years, but these effects were generally considered to be manifestations of activation of 0.and ,8-adrenergic receptors rather thap results of action of DA on a specific receptor (1). The pendulum now has swung the other way.
P H Volkman, J D Kohli, L I Goldberg
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2012
Publisher Summary This chapter focuses on the role of dopamine receptors in neurotransmission, their structures, and their functions. Dopamine (DA) is one of the major monoamine neurotransmitters in the mammalian brain. It is generated by hydroxylation and decarboxylation of the amino acid tyrosine, and further metabolized into epinephrine and ...
Nikhil M. Urs +2 more
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Publisher Summary This chapter focuses on the role of dopamine receptors in neurotransmission, their structures, and their functions. Dopamine (DA) is one of the major monoamine neurotransmitters in the mammalian brain. It is generated by hydroxylation and decarboxylation of the amino acid tyrosine, and further metabolized into epinephrine and ...
Nikhil M. Urs +2 more
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Dopamine Receptors And Hypertension
Acta Clinica Belgica, 1988Dopamine receptors and ...
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Dopamine Receptor and Hypertension
Current Medicinal Chemistry-Cardiovascular & Hematological Agents, 2005Dopamine plays an important role in the pathogenesis of hypertension by regulating epithelial sodium transport and reactive oxygen and by interacting with vasopressin, renin-angiotensin, and the sympathetic nervous system. Decreased renal dopamine production and/or impaired dopamine receptor function have been reported in hypertension.
Pedro A. Jose +3 more
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Dopamine receptor supersensitivity
Neuroscience & Biobehavioral Reviews, 1995Dopamine (DA) receptor supersensitivity refers to the phenomenon of an enhanced physiological, behavioral or biochemical response to a DA agonist. Literature related to ontogenetic aspects of this process was reviewed. Neonatal 6-hydroxydopamine (6-OHDA) destruction of rat brain DA neurons produces overt sensitization to D1 agonist-induced oral ...
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Dopamine receptor pharmacology
2007Publisher Summary This chapter discusses the basic aspects of dopamine receptor pharmacology and biology. The dopamine receptors, members of the heptahelical G-protein-coupled receptor (GPCR) superfamily, are divided into two subfamilies: the ‘D1-like’ and ‘D2-like’.
Richard B. Mailman, Xuemei Huang
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