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The Dopamine Receptors

1997
Table of Contents Preface Historical Overview: Introduction to the Dopamine Receptors Philip Seeman Gene and Promoter Structures of the Dopamine Receptors Ursula M. D'Souza Structural Basis of Dopamine Receptor Activation Irina S. Moreira, Lei Shi, Zachary Freyberg, Spencer S. Eriksen, Harel Weinstein, and Johnathan A. Javitch Dopamine Receptor Subtype-
openaire   +2 more sources

Dopamine receptors and the dopamine hypothesis of schizophrenia

Synapse, 1987
AbstractThe discovery of neuroleptic drugs in 1952 provided a new strategy for seeking a biological basis of schizophrenia. This entailed a search for a primary site of neuroleptic action. The Parkinsonian effects caused by neuroleptics suggested that dopamine transmission may be disrupted by these drugs.
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Receptor reserve at striatal dopamine receptors modulating the release of [3H]dopamine

European Journal of Pharmacology, 1988
Electrically stimulated release of [3H]dopamine [( 3H]DA) in slices of rat striatum was dose dependently inhibited by apomorphine (67% maximal inhibition) with an EC50 of 17 nM. DA receptor inactivation with N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ; 0.5 and 2 mg/kg) dose dependently shifted the ED50 for apomorphine to the right and reduced ...
Hideyasu Yokoo   +2 more
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Dopamine D2 receptors in discrimination learning and spine enlargement

Nature, 2020
Y. Iino   +6 more
semanticscholar   +1 more source

Caffeine mimics dopamine receptor agonists without stimulation of dopamine receptors

Neuropharmacology, 1986
The purpose of this study was to examine whether caffeine stimulates dopamine (DA) receptors. The effects of caffeine on the binding of [3H]spiperone to membranes from the striatum, accumulation of L-DOPA in the striatum in mice receiving gamma-butyrolactone, and regional levels of 3,4-dihydroxyphenylacetic acid in the brain of the rat were ...
H. Watanabe, H. Uramoto
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Dopamine and dopamine receptor agonists in cardiovascular therapy

Critical Care Medicine, 1990
Dopamine (DA)--previously regarded simply as the precursor of norepinephrine--is now known to have its own unique effects on cardiovascular regulation which are mediated, in part, by activating specific DA receptors. DA has long been used in the treatment of shock and heart failure.
Michael B. Murphy, William J. Elliott
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Dopamine Receptor Oligomerization

2009
Each dopamine (DA) receptor subtype physically interacts with its own kind (homomers) or other receptors (heteromers) in the plasma membrane of neurons in the basal ganglia to form dimeric or high-order receptor oligomers, termed dimeric or high-order receptor mosaics (RMs).
Fuxe K   +4 more
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Dopamine receptors: from structure to function.

Physiological Reviews, 1998
C. Missale   +4 more
semanticscholar   +1 more source

The Physiology, Signaling, and Pharmacology of Dopamine Receptors

Pharmacological Reviews, 2011
J. Beaulieu, R. Gainetdinov
semanticscholar   +1 more source

Vascular Dopamine and Dopamine Receptor Agonists

1984
Regulation and modulation of the sympathetic nervous system have been and remain cornerstone strategies for the treatment of cardiovascular disease. Whereas stimulating, mimicking or antagonizing norepinephrine and epinphrine have been the most frequently utilized approach to cardiovascular renal therapeutics, the possibility that dopamine and dopamine
Robert W. Erickson   +3 more
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