Endogenous cholinergic inputs and local circuit mechanisms govern the phasic mesolimbic dopamine response to nicotine [PDF]
Nicotine exerts its reinforcing action by stimulating nicotinic acetylcholine receptors (nAChRs) and boosting dopamine (DA) output from the ventral tegmental area (VTA).
A Taly +78 more
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Background Dopamine receptors comprise two subgroups, Gs protein-coupled “D1-like” receptors (D1, D5) and Gi-coupled “D2-like” receptors (D2, D3, D4). In airways, both dopamine D1 and D2 receptors are expressed on airway smooth muscle and regulate airway
Nao Matsuyama +8 more
doaj +1 more source
Dopaminergic activation of estrogen receptors induces fos expression within restricted regions of the neonatal female rat brain. [PDF]
Steroid receptor activation in the developing brain influences a variety of cellular processes that endure into adulthood, altering both behavior and physiology.
Kristin M Olesen, Anthony P Auger
doaj +1 more source
L-Tetrahydropalamatine: A Potential New Medication for the Treatment of Cocaine Addiction [PDF]
Levo-tetrahydropalmatine (l-THP) is an active constituent of herbal preparations containing plant species of the genera Stephania and Corydalis and has been approved and used in China for a number of clinical indications under the drug name Rotundine ...
Mantsch, John R., Wang, Jia Bei
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Dopamine receptors and organ fibrosis
Organ fibrosis, considered as a major global health concern, is a pathological condition often occurring after tissue injury in various organs. The pathogenesis of fibrosis involves multiple phases and multiple cell types. Dopamine is involved in various
ZhongLi Liao +3 more
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Dopaminergic Regulation of Neuronal Circuits in Prefrontal Cortex [PDF]
Neuromodulators, like dopamine, have considerable influence on the\ud processing capabilities of neural networks. \ud This has for instance been shown in the working memory functions\ud of prefrontal cortex, which may be regulated by altering the\ud ...
Scheler, Gabriele
core
Glucocorticoid receptor gene inactivation in dopamine-innervated areas selectively decreases behavioral responses to amphetamine [PDF]
Peer reviewedPublisher ...
Anne-Sophie eDelbes +12 more
core +6 more sources
It has been suggested that N,N-di-n-propyl-dopamine (dopamine analogue) decreased heart rate in rats through stimulation of dopamine receptors. Nevertheless, the role of prejunctional dopamine D1/2-like receptors or even α2-adrenoceptors to mediate ...
Oscar Alcántara-Vázquez +3 more
doaj +1 more source
The catecholamine neurotransmitter dopamine is classically known for regulation of central nervous system (CNS) functions such as reward, movement, and cognition. Increasing evidence also indicates that dopamine regulates critical functions in peripheral
Stephanie M. Matt +16 more
doaj +1 more source
Endogenous Dopamine and Endocannabinoid Signaling Mediate Cocaine-Induced Reversal of AMPAR Synaptic Potentiation in the Nucleus Accumbens Shell [PDF]
Repeated exposure to drugs of abuse alters the structure and function of neural circuits mediating reward, generating maladaptive plasticity in circuits critical for motivated behavior.
Hearing, Matthew +3 more
core +2 more sources

