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Dopamine Receptors: Is It Possible to Become a Therapeutic Target for Depression? [PDF]
Frontiers in Pharmacology, 2022 Dopamine and its receptors are currently recognized targets for the treatment of several neuropsychiatric disorders, including Parkinson’s disease, schizophrenia, some drug use addictions, as well as depression.
Fangyi Zhao +9 more
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Dopamine receptors and organ fibrosis [PDF]
Biochemistry and Biophysics ReportsOrgan fibrosis, considered as a major global health concern, is a pathological condition often occurring after tissue injury in various organs. The pathogenesis of fibrosis involves multiple phases and multiple cell types. Dopamine is involved in various
ZhongLi Liao +3 more
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Role of Renal Dopamine Receptors in the Regulation of Blood Pressure [PDF]
BiomoleculesHypertension continues to be a major global public health challenge. Dopamine generated in the kidney is a vital coordinator of sodium homeostasis and blood pressure control. Dopamine exerts its effects by activating its receptors, which are divided into
Jian Yang, Pedro A. Jose
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Modulation of Neuron and Astrocyte Dopamine Receptors via Receptor–Receptor Interactions [PDF]
Pharmaceuticals, 2023 Dopamine neurotransmission plays critical roles in regulating complex cognitive and behavioral processes including reward, motivation, reinforcement learning, and movement.
Diego Guidolin +6 more
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Journal of Experimental Neuroscience, 2018 Dopamine controls various physiological functions in the brain and periphery by acting on its receptors D1, D2, D3, D4, and D5. Dopamine receptors are G protein–coupled receptors involved in the regulation of motor activity and several neurological ...
Akanksha Mishra +2 more
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Synaptic enrichment and dynamic regulation of the two opposing dopamine receptors within the same neurons [PDF]
eLifeDopamine can play opposing physiological roles depending on the receptor subtype. In the fruit fly Drosophila melanogaster, Dop1R1 and Dop2R encode the D1- and D2-like receptors, respectively, and are reported to oppositely regulate intracellular cAMP ...
Shun Hiramatsu +6 more
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Tetrahydrocannabinol and dopamine D1 receptor
Frontiers in Neuroscience, 2023 Dopamine, a neurotransmitter and neuromodulator, is primarily released by dopaminergic neurons in the midbrain, particularly in the substantia nigra and the ventral tegmental area (VTA).
Jiwon Lee
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The Role of the Renal Dopaminergic System and Oxidative Stress in the Pathogenesis of Hypertension
Biomedicines, 2021 The kidney is critical in the long-term regulation of blood pressure. Oxidative stress is one of the many factors that is accountable for the development of hypertension.
Waleed N. Qaddumi, Pedro A. Jose
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Dopamine in Health and Disease: Much More Than a Neurotransmitter
Biomedicines, 2021 Dopamine is derived from an amino acid, phenylalanine, which must be obtained through the diet. Dopamine, known primarily to be a neurotransmitter involved in almost any higher executive action, acts through five types of G-protein-coupled receptors ...
Rafael Franco +2 more
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Decoding the dopamine signal in macaque prefrontal cortex: a simulation study using the Cx3Dp simulator. [PDF]
PLoS ONE, 2013 Dopamine transmission in the prefrontal cortex plays an important role in reward based learning, working memory and attention. Dopamine is thought to be released non-synaptically into the extracellular space and to reach distant receptors through ...
Isabelle Ayumi Spühler, Andreas Hauri
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