Results 31 to 40 of about 128,837 (259)

Cardiovascular Dopamine Receptors: Role of Renal Dopamine and Dopamine Receptors in Sodium Excretion [PDF]

Pharmacology & Toxicology, 1990
Research efforts in the area of peripheral dopamine have now established the presence of two distinct subtypes--DA1 and DA2--of DA receptors, and have identified a potential role for dopamine produced within the kidney in the control of renal sodium excretion.
M F, Lokhandwala, S S, Hegde
openaire   +2 more sources

D2-Like Receptors Mediate Dopamine-Inhibited Insulin Secretion via Ion Channels in Rat Pancreatic β-Cells

Frontiers in Endocrinology, 2020
Dopamine (DA) has a vital role in the central nervous system and also modulates lipid and glucose metabolism. The present study aimed to investigate the effect of dopamine on insulin secretion and the underlying mechanisms in rat pancreatic β-cells. Data
Mengmeng Liu, Lele Ren, Xiangqin Zhong, Yaqin Ding, Tao Liu, Tao Liu, Zhihong Liu, Zhihong Liu, Xiaohua Yang, Lijuan Cui, Lijuan Cui, Lijun Yang, Yanying Fan, Yunfeng Liu, Yi Zhang, Yi Zhang   +15 more
doaj   +1 more source

Purkinje cell dopaminergic inputs to astrocytes regulate cerebellar-dependent behavior

Nature Communications, 2023
The role of dopamine in the cerebellum remains relatively unexplored. Here, the authors report a dopamine system in the cerebellum in mice, where Purkinje cells supply dopamine and Bergmann glia express D1 receptors.
Chang Li, Natalie B. Saliba, Hannah Martin, Nicole A. Losurdo, Kian Kolahdouzan, Riyan Siddiqui, Destynie Medeiros, Wei Li   +7 more
doaj   +1 more source

Conformation of dopamine at the dopamine receptor. [PDF]

Proceedings of the National Academy of Sciences, 1978
Tritiated dopamine was used to label the dopamine receptor in membranes isolated from the rat corpus striatum. Scatchard analysis of displacement of [3H]dopamine by nonradioactive dopamine indicated the presence of two binding sites. The similarities in affinity, capacity, and drug specificity of the high-affinity site in the striatal membranes from ...
H L, Komiskey, J F, Bossart, D D, Miller, P N, Patil   +3 more
openaire   +2 more sources

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro

BMC Neuroscience, 2006
Background The striatal complex is the major target of dopamine action in the CNS. There, medium-spiny GABAergic neurons, which constitute about 95% of the neurons in the area, form a mutually inhibitory synaptic network that is modulated by dopamine ...
Joyce Myra P, Schulman Joshua J, Feldman Igor G, Norris J Madison, Geldwert Daron, Rayport Stephen   +5 more
doaj   +1 more source

Interactions between Histamine H1 and H3 and Dopamine D1 Receptors on feeding behavior in chicken [PDF]

Iranian Journal of Veterinary Medicine, 2017
BACKGROUND: Brain monoamines (such as histamine and dopamine) play an important role in emotions, cognition, reward and feeding behavior. The interactions between histamine and dopamine were studied in many physiological functions but this correlation is
Masood GhandForoushan, Morteza Zendehdel, Vahab Babpour   +2 more
doaj   +1 more source

Dopamine Receptors in a Songbird Brain [PDF]

Journal of Comparative Neurology, 2010
AbstractDopamine is a key neuromodulatory transmitter in the brain. It acts through dopamine receptors to affect changes in neural activity, gene expression, and behavior. In songbirds, dopamine is released into the striatal song nucleus area X, and the levels depend on social contexts of undirected and directed singing.
Kubikova, Lubica, Wada, Kazuhiro, Jarvis, Erich D.   +2 more
openaire   +3 more sources

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Investigating the Mechanisms Involved in Scopolamine-Induced Memory Degradation [PDF]

Archives of Razi Institute
In the present study, the mechanisms involved in scopolamine-induced memory impairment have been investigated. The molecular events that take place during memory mostly include mechanisms that are seen in the acquisition phase.
Atefeh Asadi-Rizi, Leila Amjad, Mehrdad Shahrani, Hossein Amini-Khoei   +3 more
doaj   +1 more source