Results 71 to 80 of about 240,105 (210)

Role of D1/D2 dopamin receptors antagonist perphenazine in morphine analgesia and tolerance in rats

Biomolecules & Biomedicine, 2013
While opioid receptors have been implicated in the development of tolerance, the subsequent mechanisms involved in these phenomena have not been completely understood.
Ercan Ozdemir, Ihsan Bagcivan, Sinan Gursoy   +2 more
doaj   +1 more source

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress [PDF]

, 2015
In human addicts, drug relapse and craving are often provoked by stress. Since 1995, this clinical scenario has been studied using a rat model of stress-induced reinstatement of drug seeking.
A Cippitelli, A Cippitelli, A Cippitelli, A Ettenberg, A Ettenberg, A Plaza-Zabala, A Sekino, A Van't Veer, AC Hansson, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AD Le, AE Higley, AM Chirila, AM Polter, AM Thierry, AN Carey, Anh D Lê, AS Kreibich, AY Deutch, B Boutrel, B Lee, B Ribeiro Do Couto, B Setlow, B Wang, B Wang, B Wang, B Wang, B Wang, BB Land, BH Westerink, BL Lewis, BM Cox, BR Lee, C Cifani, C Li, CD Schmoutz, CJ Sanchez, CJ Sanchez, CK Nielsen, CL Pickens, CP Ford, CP O'Brien, CR Gerfen, D Economidou, D Epstein, D Funk, D Funk, D Highfield, D Highfield, D Highfield, D Liu, D Rodaros, D Rotllant, David A Baker, DC Glass, DEJ Redmond, DH Epstein, DJ Calu, DJ Calu, DM Buffalari, DM Buffalari, DM Buffalari, Douglas Funk, DR Gehlert, DR Staub, DS Zahm, DT George, DW Schulz, DW Self, E Krupitsky, EA Stone, EB Margolis, EJ Khantzian, EN Graf, EN Graf, EP Zorrilla, EP Zorrilla, F Chaouloff, F Cohen, F Georges, F Leri, F Sedki, F Weiss, FC Cruz, FJ White, G Aston-Jones, G de Guglielmo, G Zislis, GF Koob, GP Chrousos, GR Valdez, H Selye, H Yamada, HC Fox, HC Fox, J Jenkins, J Stewart, J Wang, JA Deutch, JA Gray, JA Simms, JC Umhau, JD Bremner, JD Bremner, JD Shepard, JE LeDoux, JE Morley, JJ Anker, JJ Anker, JK Richards, JK Seamans, JL McGaugh, JM Blacktop, JM Bossert, JM Bossert, JM Bossert, JM Fritschy, JN Cleck, John R Mantsch, JP McLaughlin, JP Schroeder, JR Glowa, JR Mantsch, JR Mantsch, JR Mantsch, JR Mantsch, JR McReynolds, JR Schank, JR Schank, JR Schank, JV Aldrich, JV Aldrich, K McFarland, K Van Pett, KJ Jackson, KL Conrad, KL Shelton, L Lu, L Lu, L Lu, L Lu, L Zhou, LA Briand, LE Kwako, LG Kirby, LK Vaughn, M Davis, M Davis, M Heilig, M Sakanaka, MA Ungless, MB Bannon, MD Cassell, ME Bouton, ME Bouton, ME Carroll, MEP Seligman, MF Dallman, MK Greenwald, ML Jobes, ML Price, MM Moran-Santa Maria, MM Moran-Santa Maria, MR Bruchas, MR Bruchas, MT Stefanik, MW Feltenstein, MW Feltenstein, MW Hale, N Capriles, N Omelchenko, N Sidhpura, NA Chen, NM Graziane, O Vranjkovic, O Vranjkovic, P Enrico, PE Sawchenko, PJ Fletcher, PM Beardsley, PM Beardsley, PS Regier, PV Piazza, PW Kalivas, PW Kalivas, PW Kalivas, PW Marinelli, R Ciccocioppo, R Haynes, R Kvetnansky, R Martin-Fardon, R Mongeau, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Sinha, R Takahata, RC Pierce, RC Twining, RD Weiss, RE See, RE See, RJ Smith, RM Gold, RP Vertes, RP Vertes, RP Waters, RY Moore, S Cabib, S Cohen, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Erb, S Fanous, S Geisler, S Grimwood, S Shiffman, S Stopponi, S Stopponi, S Stopponi, S Tobin, S Tobin, SA Flavin, SE Back, SF Maier, SF Maier, SG Nair, SG Nair, SG Nair, SH Ahmed, SH Ahmed, SL Grella, SM Antelman, SO Eans, SR Bornstein, SR Sesack, SV Mahler, SV Mahler, T Holdstock, T Maric, TL Bale, TR Kosten, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, U Shalev, UE Ghitza, V Deroche, VA Redila, WA Hunt, WB Cannon, WM Meil, X Liu, X Liu, X Wang, Y Buczek, Y Figueroa-Guzman, Y Nawata, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Shaham, Y Silberman, Y Zhao, Yavin Shaham, YW Chen, YY Ma, YY Ma, Z Sarnyai, ZJ Brown, ZJ Brown, ZX Xi   +291 more
core   +2 more sources

A Local Circuit Model of Learned Striatal and Dopamine Cell Responses under Probabilistic Schedules of Reward [PDF]

, 2007
Before choosing, it helps to know both the expected value signaled by a predictive cue and the associated uncertainty that the reward will be forthcoming. Recently, Fiorillo et al.
Bullock, Daniel, Tan, Can Ozan
core   +1 more source

Cholinergic Modulation of Locomotion and Striatal Dopamine Release Is Mediated by α6α4* Nicotinic Acetylcholine Receptors [PDF]

, 2010
Dopamine (DA) release in striatum is governed by firing rates of midbrain DA neurons, striatal cholinergic tone, and nicotinic ACh receptors (nAChRs) on DA presynaptic terminals.
Drenan, Ryan M., Grady, Sharon R., Lester, Henry A., Marks, Michael J., McIntosh, J. Michael, McKinney, Sheri, Miwa, Julie M., Patzlaff, Natalie E., Steele, Andrew D.   +8 more
core  

Effects of methamphetamine on locomotor activity and thalamic gene expression in leptin-deficient obese mice [PDF]

, 2017
Leptin is an adipose-derived hormone that regulates energy balance. Leptin receptors are expressed in extrahypothalamic sites and several reports showed that leptin can influence feeding and locomotor behavior via direct actions on dopaminergic neurons ...
Bisagno, Veronica, Gonzalez, Betina, Gonzalez, Candela Rocio, Urbano Suarez, Francisco Jose   +3 more
core   +2 more sources

Oral Administration of Levo-Tetrahydropalmatine Attenuates Reinstatement of Extinguished Cocaine Seeking by Cocaine, Stress or Drug-Associated Cues in Rats [PDF]

, 2011
Cocaine addiction is characterized by a persistently heightened susceptibility to drug relapse. For this reason, the identification of medications that prevent drug relapse is a critical goal of drug abuse research.
Baker, David A., Bohr, Colin, Figueroa-Guzman, Yazmin, Graf, Evan N., Li, Shi-Jiang, Mantsch, John R., Mueller, Christopher R, Vranjkovic, Oliver, Wisniewski, Samantha, Yang, Zheng   +9 more
core   +2 more sources

Pharmacology of Antiparkinsonian Agents [PDF]

, 1997
The following is a summary of a two hour class on the basic pharmacology of antiparkinsonian agents. It is presented to fourth-year pharmacy students in pharmacotherapeutics III, a course structured using team-taught modules.
Soltis, Robert P.
core   +1 more source

The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components [PDF]

, 2014
G protein-coupled receptors (GPCRs) oligomerization has emerged as a vital characteristic of receptor structure. Substantial experimental evidence supports the existence of GPCR-GPCR interactions in a coordinated and cooperative manner.
Agnati, Luigi F, Borroto-Escuela, Dasiel O, Brito, Ismel, Di Palma, Michael, Duchou, Jolien, Fuxe, Kjell, Guidolin, Diego, Oflijan, Julia, Rivera, Alicia, Romero-Fernandez, Wilber, Skieterska, Kamila, Suárez-Boomgaard, Diana, Van Craenenbroeck, Kathleen   +12 more
core   +4 more sources

Individual Differences in Dopamine Are Associated with Reward Discounting in Clinical Groups But Not in Healthy Adults. [PDF]

, 2019
Some people are more willing to make immediate, risky, or costly reward-focused choices than others, which has been hypothesized to be associated with individual differences in dopamine (DA) function.
Castrellon, Jaime J, Cowan, Ronald L, Crawford, Jennifer L, Dang, Linh C, Hsu, Ming, Samanez-Larkin, Gregory R, Seaman, Kendra L, Smith, Christopher T, Young, Jacob S, Zald, David H   +9 more
core   +1 more source

Striatal cholinergic interneurons generate beta and gamma oscillations in the corticostriatal circuit and produce motor deficits [PDF]

, 2016
Cortico-basal ganglia-thalamic (CBT) neural circuits are critical modulators of cognitive and motor function. When compromised, these circuits contribute to neurological and psychiatric disorders, such as Parkinson's disease (PD).
Bucklin, Mark, Han, Xue, Kondabolu, Krishnakanth, Kopell, Nancy, McCarthy, Michelle M., Roberts, Erik A.   +5 more
core   +1 more source