Results 1 to 10 of about 27,233 (148)

Tetrahydrocannabinol and dopamine D1 receptor

Frontiers in Neuroscience, 2023
Dopamine, a neurotransmitter and neuromodulator, is primarily released by dopaminergic neurons in the midbrain, particularly in the substantia nigra and the ventral tegmental area (VTA).
Jiwon Lee
doaj   +3 more sources

Dopamine D1 Receptor in Cancer [PDF]

Cancers, 2020
Dopamine is a biologically active compound belonging to catecholamines. It plays its roles in the human body, acting both as a circulating hormone and neurotransmitter. It acts through G-protein-coupled receptors divided into two subgroups: D1-like receptors (D1R and D5R) and D2-like receptors (D2R, D3R, D4R).
Paweł Sobczuk, Michał Łomiak, Agnieszka Cudnoch-Jędrzejewska   +2 more
openaire   +2 more sources

Correction: Tetrahydrocannabinol and dopamine D1 receptor. [PDF]

Front Neurosci
Lee J.
europepmc   +2 more sources

Pharmacological blockade of dopamine D1- or D2-receptor in the prefrontal cortex induces attentional impairment in the object-based attention test through different neuronal circuits in mice

Molecular Brain, 2021
Dopamine is a key neurotransmitter that regulates attention through dopamine D1 and D2-receptors in the prefrontal cortex (PFC). We previously developed an object-based attention test (OBAT) to evaluate attention in mice.
Bolati Wulaer, Kazuo Kunisawa, Moeka Tanabe, Aika Yanagawa, Kuniaki Saito, Akihiro Mouri, Toshitaka Nabeshima   +6 more
doaj   +1 more source

Purkinje cell dopaminergic inputs to astrocytes regulate cerebellar-dependent behavior

Nature Communications, 2023
The role of dopamine in the cerebellum remains relatively unexplored. Here, the authors report a dopamine system in the cerebellum in mice, where Purkinje cells supply dopamine and Bergmann glia express D1 receptors.
Chang Li, Natalie B. Saliba, Hannah Martin, Nicole A. Losurdo, Kian Kolahdouzan, Riyan Siddiqui, Destynie Medeiros, Wei Li   +7 more
doaj   +1 more source

Tumor suppression and improvement in immune systems by specific activation of dopamine D1-receptor-expressing neurons in the nucleus accumbens

Molecular Brain, 2022
Recent research has suggested that the mesolimbic dopamine network that mainly terminates in the nucleus accumbens may positively control the peripheral immune system.
Daisuke Sato, Yusuke Hamada, Michiko Narita, Tomohisa Mori, Hiroyuki Tezuka, Yukari Suda, Kenichi Tanaka, Sara Yoshida, Hideki Tamura, Akihiro Yamanaka, Emiko Senba, Naoko Kuzumaki, Minoru Narita   +12 more
doaj   +1 more source

Dopamine receptors antagonistically regulate behavioral choice between conflicting alternatives in C. elegans. [PDF]

PLoS ONE, 2014
Caenorhabditis elegans is a useful model to study the neuronal or molecular basis for behavioral choice, a specific form of decision-making. Although it has been implied that both D1-like and D2-like dopamine receptors may contribute to the control of ...
Daoyong Wang, Yonglin Yu, Yinxia Li, Yang Wang, Dayong Wang   +4 more
doaj   +1 more source

A Concise Review of the Conflicting Roles of Dopamine-1 versus Dopamine-2 Receptors in Wound Healing

Molecules, 2017
Catecholamines play an important regulatory role in cutaneous wound healing. The exact role of dopamine in human epidermis has yet to be fully elucidated. Current published evidence describes its differential effects on two separate families of G protein
Alexandra R. Vaughn, Michael James Davis, Raja K. Sivamani, Roslyn Rivkah Isseroff   +3 more
doaj   +1 more source

The dopamine D1 receptor is expressed and induces CREB phosphorylation and MUC5AC expression in human airway epithelium

Respiratory Research, 2018
Background Dopamine receptors comprise two subgroups, Gs protein-coupled “D1-like” receptors (D1, D5) and Gi-coupled “D2-like” receptors (D2, D3, D4). In airways, both dopamine D1 and D2 receptors are expressed on airway smooth muscle and regulate airway
Nao Matsuyama, Sumire Shibata, Atsuko Matoba, Tada-aki Kudo, Jennifer Danielsson, Atsushi Kohjitani, Eiji Masaki, Charles W. Emala, Kentaro Mizuta   +8 more
doaj   +1 more source

Heterodimeric D1-D2 dopamine receptors: a review [PDF]

Biomeditsinskaya Khimiya, 2017
This review summarizes modern data on the structure and functions ofheteromersformed by D1 and D2 dopamine receptors focusing on their role in the mechanisms of drug dependence. This article discusses potential functional significance of heterodimeric D1-D2 dopamine receptorsdue to their localization in the brain as well as unique pharmacological ...
N L, Vekshina, P K, Anokhin, A G, Veretinskaya, I Yu, Shamakina   +3 more
openaire   +2 more sources