Results 21 to 30 of about 27,293 (207)
Journal of Pharmacological Sciences, 2012 Among numerous mechanisms implicated in the regulation of orofacial movements, dopamine-containing neurons have received the most extensive study. Here we review the effects of a) constitutive knockout of D1–5 dopamine receptors and b) conditional ...
Katsunori Tomiyama +3 more
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Dopamine D1 receptor development depends on endogenous dopamine
Developmental Brain Research, 1990 Profound depletion of forebrain dopamine by 6-hydroxydopamine in neonatal rats (day 3) was associated with up to 82% loss of D1 receptor sites labeled with [3H]SCH-23390 at day 21. Administration of the selective D1 agonist SKF-38393 (days 6-18) abolished the correlation between D1 receptor density and DA concentrations, even with greater than 99 ...
H A, Gelbard +6 more
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Advanced Biomedical Research, 2022 Background: In the present study, the effects of intra-basolateral amygdala (BLA) blockade of dopamine D1 receptor on morphine-induced conditioned place preference (CPP) were investigated in male Wistar rats.
Zahra Rezaei +2 more
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Dopamine and dopamine receptor D1 associated with decreased social interaction [PDF]
Behavioural Brain Research, 2017 Deficits in social interaction are hallmarks of neurological and psychiatric disorders. However, its underlying mechanism is still unclear. Here, we show that the loss of dendritic cell factor 1 (Dcf1) in the nervous system of mice induces social interaction deficiency, autism-like behaviour, and influences social interaction via the dopamine system ...
Qiang, Liu +3 more
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Frontiers in Neuroscience, 2015 Dopamine is an important central nervous system transmitter that functions through two classes of receptors (D1 and D2) to influence a diverse range of biological processes in vertebrates.
Asher eHaug-Baltzell +8 more
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Modulation of Adenylyl Cyclase Activity in Rat Striatal Homogenate by Dopaminergic Receptors
Journal of Pharmacological Sciences, 2008 We have characterized the modulation of adenylyl cyclase (AC) activity by ligands of dopaminergic receptors in rat striatal homogenate and compared the results with receptor-ligand binding affinities.
Argo Vonk, Reet Reinart, Ago Rinken
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The role of intracerebral dopamine D1 and D2 receptors in sleep‐wake cycles and general anesthesia
Ibrain, 2022 Dopamine (DA), a monoamine neurotransmitter, is synthesized and released mainly by neurons in the ventral tegmental area and the substantia nigra (SN) pars compacta of the midbrain.
Jie Zhang +5 more
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Amphetamine Promotes Cortical Up State in Part Via Dopamine Receptors
Frontiers in Pharmacology, 2021 Cortical neurons oscillate between Up and Down states during slow wave sleep and general anesthesia. Recent studies show that Up/Down oscillations also occur during quiet wakefulness.
Guofang Shen, Wei-Xing Shi, Wei-Xing Shi
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Altered D1 dopamine receptor trafficking in parkinsonian and dyskinetic non-human primates
Neurobiology of Disease, 2007 Dyskinesias represent a debilitating complication of levodopa therapy for Parkinson's disease (PD). While we recently demonstrated that levodopa-induced dyskinesia results from increased dopamine D1 receptor-mediated transmission, we also questioned the ...
Céline Guigoni +4 more
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Dopamine D1 Receptor Regulation of Phospholipase C
Hypertension Research, 1995 Dopamine is an endogenous catecholamine which exerts its actions by occupancy of specific receptors. Dopamine receptors are classified into two main groups: the two cloned D1-like receptors (D1A and D1B in rats; D1B is also known as D5 in humans) are linked to stimulation of adenylyl cyclase, while the three cloned D2-like receptors (D2 or D2A, D3 or ...
P A, Jose +6 more
openaire +3 more sources