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Glycosylation of Erythropoietin Receptor
1991The size of the murine erythropoietin (EPO) receptor (EPO-R), 105 kDa, estimated from EPO.EPO-R cross-linked products,is much higher than that, 53 kDa, predicted from EPO-R cDNA. The lectinbinding properties of the solubilized EPO-R suggested that EPO-R was N-glycosylated. To find whether glycosylation of EPO-R accounted for the difference in size, the
S. Masuda, Y. Hisada, M. Ueda, R. Sasaki
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Characterization of murine erythropoietin receptor genes
Journal of Molecular Biology, 1990We have isolated and characterized the murine genomic and complementary DNAs encoding erythropoietin (Epo) receptor from Epo-responsive and unresponsive mouse erythroleukemia cells. Two classes of Epo receptor cDNAs were isolated from Epo-responsive cells. One is a 55,000 Mr membrane-bound Epo receptor, and the other is a 29,000 Mr soluble Epo receptor
S, Kuramochi, Y, Ikawa, K, Todokoro
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Erythropoietin and Erythropoietin Receptor Expression in Vestibular Schwannoma
Otology & Neurotology, 2007Hypoxia-inducible factor (HIF)-1alpha, erythropoietin (Epo), Epo receptor (EpoR), and bcl-2 are expressed in both sporadic unilateral vestibular schwannomas (VSs) and those associated with neurofibromatosis Type 2, and the expression data correlate with clinicopathological tumor features including microvessel density and Ki-67-labeling index ...
Marc, Diensthuber +6 more
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Neurosurgery, 2005
Erythropoietin (EPO) is a pleiotropic cytokine originally identified for its role in erythropoiesis. Recent studies have demonstrated that EPO and its receptor (EPO-R) are expressed in the central nervous system, where EPO exerts neuroprotective functions. Because the expression of the EPO and EPO-R network is poorly investigated in the central nervous
GRASSO, Giovanni +7 more
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Erythropoietin (EPO) is a pleiotropic cytokine originally identified for its role in erythropoiesis. Recent studies have demonstrated that EPO and its receptor (EPO-R) are expressed in the central nervous system, where EPO exerts neuroprotective functions. Because the expression of the EPO and EPO-R network is poorly investigated in the central nervous
GRASSO, Giovanni +7 more
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Erythropoietin and erythropoietin receptor expression in human cancer.
Cancer research, 2001Erythropoietin (EPO) stimulates the growth of erythroblasts in the bone marrow (C. Lacombe and P. Mayeux, NEPHROL: DIAL: TRANSPLANT:, 14 (SUPPL: 2): 22-28, 1999). We report basal and hypoxia-stimulated expression of EPO and its receptor, EPOR, in human breast cancer cells, and we demonstrate EPO-stimulated tyrosine phosphorylation and the proliferation
G, Acs +6 more
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A Randomized Trial of Erythropoietin for Neuroprotection in Preterm Infants
New England Journal of Medicine, 2020Sandra E Juul +2 more
exaly
Trial of Erythropoietin for Hypoxic–Ischemic Encephalopathy in Newborns
New England Journal of Medicine, 2022Yvonne W Wu +2 more
exaly
Seikagaku. The Journal of Japanese Biochemical Society, 1991
S, Masuda, R, Sasaki
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S, Masuda, R, Sasaki
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Erythropoietin in traumatic brain injury (EPO-TBI): a double-blind randomised controlled trial
Lancet, The, 2015Alistair Nichol +2 more
exaly

