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Estrogen and estrogen receptors in kidney diseases [PDF]
Renal Failure, 2021 Acute kidney injury (AKI) and chronic kidney disease (CKD) are posing great threats to global health within this century. Studies have suggested that estrogen and estrogen receptors (ERs) play important roles in many physiological processes in the kidney.
Hao-Yang Ma, Shuang Chen, Yang Du
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Frontiers in Cellular Neuroscience, 2021 Estrogens and estrogen-like molecules can modify the biology of several cell types. Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of estrogen receptors, while the G protein-coupled estrogen receptor 1 (GPER-1 ...
Felipe A. Bustamante-Barrientos +14 more
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Estrogen-Receptor Expression and Function in Female Reproductive Disease
Cells, 2019 Estrogen receptors (ER) include ER alpha, ER beta and new membrane receptor G protein-coupled receptor 30 (GPR30). Estrogen receptors are key receptors to maintain ovarian granulosa cell differentiation, follicle and oocyte growth and development, and ...
Zi-Run Tang +4 more
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Estrogen, Angiogenesis, Immunity and Cell Metabolism: Solving the Puzzle [PDF]
International Journal of Molecular Sciences, 2018 Estrogen plays an important role in the regulation of cardiovascular physiology and the immune system by inducing direct effects on multiple cell types including immune and vascular cells. Sex steroid hormones are implicated in cardiovascular protection,
Annalisa Trenti +5 more
semanticscholar +4 more sources
Endocrine-Disrupting Activities of Flavones on Steroid Receptors: Structural Requirements and Synthesis of Novel Flavone with Improved Estrogenic Activity [PDF]
BiomedicinesBackground/Objectives: Flavonoids are common ubiquitous components of plants and are consumed by humans and livestock in their diets. Many different activities have been proposed for a variety of flavonoids that play a role in the benefits of a plant ...
Steven K. Nordeen +5 more
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Research progress on estrogen and its receptors in occurrence and advance of Crohn's disease [PDF]
Jichu yixue yu linchuang, 2022 Crohn's disease (CD) is a subtype of inflammatory bowel diseases and may be resulted from endocrine disorders. Estrogen and its receptors exert an important role in the pathogenesis of CD.
WU Guo-zhi, AN Li-na, LIU Min, WANG Yu-ping, GUO Qing-hong
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International Journal of Molecular Sciences, 2023 Estrogen is an essential sex steroid hormone that functions primarily in female reproductive system, as well as in a variety of tissues and organs with pleiotropic effects, such as in cardiovascular, nervous, immune, and musculoskeletal systems.
Kenta Yoh, K. Ikeda, K. Horie, S. Inoue
semanticscholar +1 more source
Membrane estrogen signaling in female reproduction and motivation
Frontiers in Endocrinology, 2022 Estrogen receptors were initially identified in the uterus, and later throughout the brain and body as intracellular, ligand-regulated transcription factors that affect genomic change upon ligand binding.
Caroline S. Johnson +2 more
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Role of estrogen receptors in health and disease
Frontiers in Endocrinology, 2022 Estrogen receptors (ERs) regulate multiple complex physiological processes in humans. Abnormal ER signaling may result in various disorders, including reproductive system-related disorders (endometriosis, and breast, ovarian, and prostate cancer), bone ...
Pengcheng Chen, Bo Li, Ou-Yang Ling
semanticscholar +1 more source
Cells, 2022 Voltage-gated calcium channels (VGCCs) and estrogen receptors are important cellular proteins that have been shown to interact with each other across varied cells and tissues.
Yashashwini Dinesh Subbamanda +1 more
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