Results 171 to 180 of about 2,636,320 (328)
Comprehensive genetic analysis of poorly differentiated gastric cancer in young females
Annals of Gastroenterological Surgery, EarlyView.Although the involvement of female sex hormones in the development of poorly differentiated gastric cancer in young females is controversial, our detailed analysis using RNA‐seq suggested that the female sex hormone, β‐estradiol plays a role in the development of poorly differentiated gastric cancer in young females. Abstract Aim The reasons behind the
Nobuhiro Nakazawa +9 more
wiley +1 more source
Journal of Pharmacological Sciences, 2014 .: We previously reported the occurrence and function of plasma membrane estrogen receptors in cultured bovine adrenal medullary cells. Here we report the effects of raloxifene and tamoxifen, selective estrogen receptor modulators, on plasma membrane ...
Hirohide Inagaki +8 more
doaj
Machine‐Learning‐Guided Analysis of Breast Tumor Malignancy Based on Nuclear Morphological Features
Advanced Intelligent Discovery, EarlyView.Through statistical and machine learning approaches, we evaluate a clinically relevant dataset comprising more than 500 instances of patient breast tumor nuclei with 10 size and shape features. Our study underscores the significance of nuclear morphological features as potential breast tumor malignancy biomarkers and their combined use with statistical
Aditi Birwadkar +3 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.Exosomes are emerging as powerful biomarkers for disease diagnosis and monitoring. This review highlights the integration of surface‐enhanced Raman spectroscopy with artificial intelligence to enhance molecular fingerprinting of exosomes. Machine learning and deep learning techniques improve spectral interpretation, enabling accurate classification of ...
Munevver Akdeniz +2 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Cardiac rhabdomyomas are often the presenting sign of tuberous sclerosis complex (TSC). Prior reports have shown that maternal sirolimus treatment can reduce rhabdomyomas. We used maternal sirolimus to reverse hydrops fetalis due to a massive cardiac rhabdomyoma in a twin gestation.
David M. Ritter +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.A rotaxane actuator controls bond scission—perpendicular or parallel to the axle—based on bulky group orientation in a 4‐membered ring. This allows diverse functional molecules to be released from a single core structure, expanding the molecular variety obtainable from new or existing mechanophores.
Lei Chen, Guillaume De Bo
wiley +2 more sources
Prognostic significance of steroid hormone receptors (ER and PR) in primary operable breast cancer [PDF]
Archive of Oncology, 2002 Kanjer Ksenija +4 more
doaj +1 more source
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.ABSTRACT Women with the FMR1 premutation (FXpm) are at heightened genetic vulnerability for depression, with risk compounded by the stressors of parenting a disabled child. Although risk factors persist as FXpm women age, depression in FXpm mothers during midlife and old age is poorly characterized. This study used an accelerated longitudinal design to
Jessica Klusek +8 more
wiley +1 more source
American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.ABSTRACT Turner syndrome (TS) is frequently complicated by congenital heart disease (CHD). While left‐sided lesions such as bicuspid aortic valve (BAV) and coarctation of the aorta are the most common structural heart lesions in TS, other anomalies, such as aortic arch malformations, hypoplastic left heart syndrome (HLHS), persistent left superior vena
Katya de Groote +9 more
wiley +1 more source
Estrogen receptors regulate innate immune cells and signaling pathways
Cellular Immunology, 2015 S. Kovats
semanticscholar +1 more source