Results 11 to 20 of about 127,469 (270)

Analysis of the molecular subtypes of preoperative core needle biopsy and surgical specimens in invasive breast cancer [PDF]

Journal of Pathology and Translational Medicine, 2020
Background Accurate molecular classification of breast core needle biopsy (CNB) tissue is important for determining neoadjuvant systemic therapies for invasive breast cancer.
Ye Sul Jeong, Jun Kang, Jieun Lee, Tae-Kyung Yoo, Sung Hun Kim, Ahwon Lee   +5 more
doaj   +1 more source

The Impact of Estrogen and Estrogen-Like Molecules in Neurogenesis and Neurodegeneration: Beneficial or Harmful?

Frontiers in Cellular Neuroscience, 2021
Estrogens and estrogen-like molecules can modify the biology of several cell types. Estrogen receptors alpha (ERα) and beta (ERβ) belong to the so-called classical family of estrogen receptors, while the G protein-coupled estrogen receptor 1 (GPER-1 ...
Felipe A. Bustamante-Barrientos, Felipe A. Bustamante-Barrientos, Maxs Méndez-Ruette, Alexander Ortloff, Patricia Luz-Crawford, Patricia Luz-Crawford, Francisco J. Rivera, Francisco J. Rivera, Francisco J. Rivera, Francisco J. Rivera, Carlos D. Figueroa, Carlos D. Figueroa, Luis Molina, Luis Federico Bátiz, Luis Federico Bátiz   +14 more
doaj   +1 more source

A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song, Jiahui Xu, Wei Yuan, Ruixue Li, Hui Guo, Hanshu Gao, Cuiying Gu, Wenjing Feng, Yanan Ma, Haiqiang Guo, Zhaoqing Sun, Liqiang Zheng   +11 more
wiley   +1 more source

Estrogen Receptors and Endothelium [PDF]

Arteriosclerosis, Thrombosis, and Vascular Biology, 2010
Estrogens, and in particular 17β-estradiol (E2), play a pivotal role in sexual development and reproduction and are also implicated in a large number of physiological processes, including the cardiovascular system. Both acetylcholine-induced and flow-dependent vasodilation are preserved or potentiated by estrogen treatment in both animal models and ...
Arnal, Jean-François, Fontaine, Coralie, Billon-Galés, Audrey, Favre, Julie, Laurell, Henrik, Lenfant, Françoise, Gourdy, Pierre   +6 more
openaire   +4 more sources

Effects of pregnancy on neuromyelitis optica spectrum disorder and predictors of related attacks

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1918-1925, December 2022., 2022
Abstract Objective Our study aimed to investigate the influence of pregnancy on the course of neuromyelitis optica spectrum disorders (NMOSD) and to explore the independent predictors of pregnancy‐related attacks. Methods We performed a retrospective study of patients with NMOSD based on the Wingerchuk 2006 or the revised Wingerchuk 2015 criteria ...
Qin Du, Ziyan Shi, Hongxi Chen, Ying Zhang, Yuhan Qiu, Yanlin Lang, Lingyao Kong, Hongyu Zhou   +7 more
wiley   +1 more source

Expression of female sex hormone receptors and its relation to clinicopathological characteristics and prognosis of lung adenocarcinoma [PDF]

Journal of Pathology and Translational Medicine, 2020
Background Adenocarcinoma (ADC) of the lung exhibits different clinicopathological characteristics in men and women. Recent studies have suggested that these differences originate from the expression of female sex hormone receptors in tumor cells.
Jin Hwan Lee, Han Kyeom Kim, Bong Kyung Shin   +2 more
doaj   +1 more source

Estrogen, Estrogen Receptor and Lung Cancer [PDF]

International Journal of Molecular Sciences, 2017
Estrogen has been postulated as a contributor for lung cancer development and progression. We reviewed the current knowledge about the expression and prognostic implications of the estrogen receptors (ER) in lung cancer, the effect and signaling pathway of estrogen on lung cancer, the hormone replacement therapy and lung cancer risk and survival, the ...
Li-Han Hsu, Nei-Min Chu, Shu-Huei Kao
openaire   +3 more sources

Support Vector Machine classifier for estrogen receptor positive and negative early-onset breast cancer. [PDF]

PLoS ONE, 2013
Two major breast cancer sub-types are defined by the expression of estrogen receptors on tumour cells. Cancers with large numbers of receptors are termed estrogen receptor positive and those with few are estrogen receptor negative.
Rosanna Upstill-Goddard, Diana Eccles, Sarah Ennis, Sajjad Rafiq, William Tapper, Joerg Fliege, Andrew Collins   +6 more
doaj   +1 more source

A Review on Sex Steroid Hormone Estrogen Receptors in Mammals and Fish

International Journal of Endocrinology, 2020
Steroid hormones play essential roles in the reproductive biology of vertebrates. Estrogen exercises its effect through estrogen receptors and is not only a female reproductive hormone but acts virtually in all vertebrates, including fish, and is ...
Eric Amenyogbe, Gang Chen, Zhongliang Wang, Xiaoying Lu, Mingde Lin, Ai Ying Lin   +5 more
doaj   +1 more source

The Role of G Protein-Coupled Estrogen Receptor (GPER) in Vascular Pathology and Physiology

Biomolecules, 2023
Objective: Estrogen is indispensable in health and disease and mainly functions through its receptors. The protection of the cardiovascular system by estrogen and its receptors has been recognized for decades.
Fujie Xu, Jipeng Ma, Xiaowu Wang, Xiaoya Wang, Weiyi Fang, Jingwei Sun, Zilin Li, Jincheng Liu   +7 more
doaj   +1 more source