Advanced Science, EarlyView.HmmyCAFs may form a triple immunosuppressive niche: possibly secrete ECM (POSTN, etc.) as physical barriers to block CD8⁺ T cells, induce CD8⁺ T exhaustion via those molecules, and use HIF‐1α‐driven metabolism to create acidic, nutrient‐poor microenvironments that suppress T cells.
Yingxue Li +12 more
wiley +1 more source
Progress of estrogen receptor and spliceosome in endometrial carcinoma. [PDF]
Front Endocrinol (Lausanne)Hong Z, Mo T, Zhou P, Chen J, Li X.
europepmc +1 more source
Pushing Biomolecule Detection Limit With Graphene Field‐effect Transistor Biosensors
Advanced Electronic Materials, EarlyView.Graphene knows your health! This work presents a comprehensive overview of recent advances in graphene field‐effect transistor (GFET) biosensors for ultrasensitive biomolecule detection. How device engineering, high‐mobility graphene synthesis, and tailored surface chemistry push detection limits is highlighted, while discussing emerging strategies ...
Co Dang Pham +4 more
wiley +1 more source
Estrogen Modulation of B Cell Immunity: Implications for HIV Control and Therapeutic Strategies. [PDF]
Compr PhysiolKasibante J +3 more
europepmc +1 more source
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Although surgical treatment is the primary measure for patients with perforated peptic ulcer (PPU), nonoperative management (NOM) has become a common alternative. However, risk score models predicting the success of NOM based on the analysis of a large number of patients remain scarce.
Kei Ito +12 more
wiley +1 more source
Maternal Thymus Adaptations and Hormone Regulation During Pregnancy. [PDF]
CellsYang L, Wang X, Zhang L.
europepmc +1 more source
Nanozymes for Non‐Neoplastic Diseases: Catalytic Therapy Redefined
Aggregate, EarlyView.Non‐neoplastic diseases pose a significant health burden. Nanozymes, enzyme‐like nanomaterials, offer promising strategies for regulating oxidative stress and inflammation. This review explores their development, structure–function relationships, and therapeutic potential, with a focus on precision medicine through targeted delivery and multimodal ...
Ling Mei +8 more
wiley +1 more source
Effects of 17a-ethinyl estradiol exposure on estrogen receptors a and ß and vitellogenins A, B and C mRNA expression in the liver of sand goby (Pomatoschistus minutus) [PDF]
, 2014 Craft, John +4 more
core +1 more source
Effectiveness of papaya leaf extract (<i>Carica papaya</i> L.) as an infertility agent on estrus cycle length and expression of estrogen receptor beta on ovaries of female white rats (<i>Rattus norvegicus</i>). [PDF]
Open Vet JHendrawan VF +4 more
europepmc +1 more source
Machine‐Learning‐Guided Analysis of Breast Tumor Malignancy Based on Nuclear Morphological Features
Advanced Intelligent Discovery, EarlyView.Through statistical and machine learning approaches, we evaluate a clinically relevant dataset comprising more than 500 instances of patient breast tumor nuclei with 10 size and shape features. Our study underscores the significance of nuclear morphological features as potential breast tumor malignancy biomarkers and their combined use with statistical
Aditi Birwadkar +3 more
wiley +1 more source