Results 261 to 270 of about 258,016 (314)
Hormone replacement therapy in female-specific cancer survivors: considerations beyond cancer cure. [PDF]
Jpn J Clin OncolYoshihama T +3 more
europepmc +1 more source
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Estrogens, estrogen receptors and melanoma
Expert Review of Anticancer Therapy, 2011The skin is the largest nonreproductive target tissue on which estrogen plays many beneficial and protective roles. Although neither exogenous hormones nor pregnancy represent significant risk factors for melanoma, epidemiological data suggest a higher survival rate in women with metastatic disease versus men and in premenopausal versus postmenopausal ...
Vincenzo De Giorgi +8 more
openaire +3 more sources
Journal of Mammary Gland Biology and Neoplasia, 1998
Estrogen receptor (ER)3 gene expression in breast epithelium is an intricately regulated event. The human ER gene is transcribed from at least three different promoters which are expressed in a cell- and tissue-specific manner, and result in mRNA isoforms with unique 5'-untranslated exons.
Suzanne A. W. Fuqua, Torsten A. Hopp
openaire +2 more sources
Estrogen receptor (ER)3 gene expression in breast epithelium is an intricately regulated event. The human ER gene is transcribed from at least three different promoters which are expressed in a cell- and tissue-specific manner, and result in mRNA isoforms with unique 5'-untranslated exons.
Suzanne A. W. Fuqua, Torsten A. Hopp
openaire +2 more sources
Critical Reviews in Eukaryotic Gene Expression, 2002
Today we have to consider the existence of two estrogen receptors, alpha and beta, in our attempts to understand the role of estrogen receptors in physiology and pathology, and to explain the pharmacology of estrogens, antiestrogens, and SERMs. Both ERalpha and ERbeta belong to the large family of nuclear receptors that function as hormone-dependent ...
Stefan Nilsson, Jan-Åke Gustafsson
openaire +3 more sources
Today we have to consider the existence of two estrogen receptors, alpha and beta, in our attempts to understand the role of estrogen receptors in physiology and pathology, and to explain the pharmacology of estrogens, antiestrogens, and SERMs. Both ERalpha and ERbeta belong to the large family of nuclear receptors that function as hormone-dependent ...
Stefan Nilsson, Jan-Åke Gustafsson
openaire +3 more sources
Molecular and Cellular Endocrinology, 1998
The purpose of this paper is to review potential novel functional pathways by which estradiol and estrogenic compounds elicit biological responses in mammals. We will limit our approach to those novel functions suggested by phenotypes associated with estrogen receptor-alpha (ER alpha) gene mutations and polymorphisms.
Dennis B. Lubahn +2 more
openaire +3 more sources
The purpose of this paper is to review potential novel functional pathways by which estradiol and estrogenic compounds elicit biological responses in mammals. We will limit our approach to those novel functions suggested by phenotypes associated with estrogen receptor-alpha (ER alpha) gene mutations and polymorphisms.
Dennis B. Lubahn +2 more
openaire +3 more sources
Estrogen or estrogen receptor?
Trends in Endocrinology & Metabolism, 2003View Large Image | Download PowerPoint SlideAs a clinical breast oncologist, I was eager to review Endocrine Therapy in Breast Cancer. Hormonal manipulation has been the predominant form of breast cancer treatment for >50 years. Surgical ablation, high-dose estrogens, LHRH agonists and antiestrogens have all shown clinical benefit.
openaire +2 more sources
Estrogen receptors in the pancreas
Journal of Steroid Biochemistry, 1974Minced rat pancreas retained a large portion of estradiol (E2) after incubation with either 5 nM or 1 μM concentrations of radioactive E2. The mince was homogenized in low salt buffer and separated into nuclei, mitochondria, microsomes, and cytosol by centrifugations at 1000 g, 10,000 g, and 105,000 g, respectively.
Hannah E. Rosenthal, Avery A. Sandberg
openaire +2 more sources
Estrogen receptor phosphorylation [PDF]
Steroids, 2003 Estrogen receptor alpha (ERalpha) is phosphorylated on multiple amino acid residues. For example, in response to estradiol binding, human ERalpha is predominately phosphorylated on Ser-118 and to a lesser extent on Ser-104 and Ser-106. In response to activation of the mitogen-activated protein kinase pathway, phosphorylation occurs on Ser-118 and Ser ...
openaire +2 more sources