Results 291 to 300 of about 2,636,320 (328)

Estrogen or estrogen receptor?

Trends in Endocrinology & Metabolism, 2003
View Large Image | Download PowerPoint SlideAs a clinical breast oncologist, I was eager to review Endocrine Therapy in Breast Cancer. Hormonal manipulation has been the predominant form of breast cancer treatment for >50 years. Surgical ablation, high-dose estrogens, LHRH agonists and antiestrogens have all shown clinical benefit.
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Estrogen receptors in the pancreas

Journal of Steroid Biochemistry, 1974
Minced rat pancreas retained a large portion of estradiol (E2) after incubation with either 5 nM or 1 μM concentrations of radioactive E2. The mince was homogenized in low salt buffer and separated into nuclei, mitochondria, microsomes, and cytosol by centrifugations at 1000 g, 10,000 g, and 105,000 g, respectively.
Hannah E. Rosenthal, Avery A. Sandberg
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Seasonal expression of androgen receptors, estrogen receptors, and aromatase in the canary brain in relation to circulating androgens and estrogens.

Journal of Neurobiology, 2000
Songbirds have a complex neural network for learning and production of song, namely the neural song system. Several nuclei of the song system contain androgen receptors (AR), and the neostriatal nucleus HVc also contains alpha type estrogen receptors (ER)
L. Fusani, T. Hof, J. Hutchison, M. Gahr
semanticscholar   +1 more source

Estrogen receptors: how do they signal and what are their targets.

Physiological Reviews, 2007
During the past decade there has been a substantial advance in our understanding of estrogen signaling both from a clinical as well as a preclinical perspective.
N. Heldring, A. Pike, S. Andersson, J. Matthews, G. Cheng, J. Hartman, M. Tujague, A. Ström, E. Treuter, M. Warner, J. Gustafsson   +10 more
semanticscholar   +1 more source

The standardization of estrogen receptors

The Journal of Steroid Biochemistry and Molecular Biology, 1993
Tumour estrogen receptor (ER) status may determine the medical treatment of a patient with breast cancer; yet inter-laboratory results can vary markedly, particularly when absolute cut-offs in fmol/mg cytosol protein are used. The use of standardized log units is proposed to permit greater inter-laboratory comparability.
B.G. Mobbs, David R. McCready, Maureen E. Trudeau, Teik Chye Ooi, Carol Sawka, Eugene R. Tustanoff, Eamonn D. Ryan, H. Lavina A. Lickley, Wedad Hanna, Judy-Anne W. Chapman, Kathleen I. Pritchard, Donald J.A. Sutherland   +11 more
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The estrogen receptor family

Current Opinion in Obstetrics and Gynaecology, 1999
A significant flow of new data is currently being generated within the field of estrogen receptors and their mechanisms of action. This is primarily a result of the development of estrogen receptor knockout mice and the discovery of the second estrogen receptor, estrogen receptor beta.
Stefan Nilsson, Margaret Warner, Jan-Ake Gustafsson   +2 more
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Fulvestrant: an estrogen receptor antagonist that downregulates the estrogen receptor

Seminars in Oncology, 2003
Fulvestrant, a novel antiestrogen classified as an estrogen receptor antagonist without known agonist effects, was recently approved in the United States for the treatment of postmenopausal, hormone receptor-positive women with progressive metastatic breast cancer after antiestrogen therapy.
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Estrogen and estrogen receptors in thyroid carcinomas

Journal of Surgical Oncology, 1991
AbstractThyroid tissues, composed of normal thyroid (10 cases), Graves' thyroid (4), and papillary carcinoma (10), were measured for the presence of receptors for estrogen (ER) using an enzyme‐immunoassay method. The mean value of ER in papillary carcinoma tissues (4.0 ± 3.6 fmol/mg protein) was higher than that in normal thyroid tissues (0.8 ± 0.4 ...
Akitaka Nonomura, Yuji Mizukami, Masakuni Noguchi, Fujitsugu Matsubara, Takuma Hashimoto, Takatoshi Michigishi   +5 more
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The Role of Estrogen and Estrogen Receptors in Chemoresistance

Current Medicinal Chemistry, 2011
Drug resistance is one of the major obstacles limiting the success of cancer chemotherapy. Biological mechanisms contributing to drug resistance may be present de novo and related to inherent features or may be raised after exposure to anticancer drugs. In recent years, both clinical observations and experimental studies suggested that steroid hormones
H Zhang, Weimin Fan, Meihua Sui
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Biological Role of Estrogen and Estrogen Receptors

Critical Reviews in Biochemistry and Molecular Biology, 2002
(2002). Biological Role of Estrogen and Estrogen Receptors. Critical Reviews in Biochemistry and Molecular Biology: Vol. 37, No. 1, pp. 1-28.
Jan-Åke Gustafsson, Stefan Nilsson
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