Endometrial Progesterone and Estrogen Receptors in Relation to Hormonal Levels in Women with Unexplained Recurrent Miscarriage [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2023 Objective Recurrent miscarriage has been linked to hormonal disturbance due to dysregulation of its receptors rather than to the availability of the hormone.
Ihab Adel Gomaa +4 more
doaj +1 more source
FMO Study of the Interaction Energy between Human Estrogen Receptor $α$ and Selected Ligands [PDF]
arXiv, 2022 Fragment molecular orbital (FMO) calculations were performed in aqueous media which allowed us to obtain the interaction energy between the human estrogen receptor $\alpha$ ligand-binding domain (ER) and the selected ligands (L): 17$\beta$-estradiol (E2), 17$\alpha$-estradiol (17$\alpha$-E2), estriol (E3), genistein (GNT), diethylstilbestrol (DES ...
arxiv
The binding of estrogen and estrogen antagonists to the estrogen receptor
Archives of Biochemistry and Biophysics, 1992 The model of the estrogen receptor as a dimer of identical, interacting subunits and data obtained by Sasson and Notides (1988, Mol. Endocrinol. 2, 307-312) were used to find the standard free energy changes that describe the binding of estradiol and 4-hydroxytamoxifen to the estrogen receptor.
Shlomo Sasson +2 more
openaire +3 more sources
Dual-path convolutional neural network using micro-FTIR imaging to predict breast cancer subtypes and biomarkers levels: estrogen receptor, progesterone receptor, HER2 and Ki67 [PDF]
arXiv, 2023 Breast cancer molecular subtypes classification plays an import role to sort patients with divergent prognosis. The biomarkers used are Estrogen Receptor (ER), Progesterone Receptor (PR), HER2, and Ki67. Based on these biomarkers expression levels, subtypes are classified as Luminal A (LA), Luminal B (LB), HER2 subtype, and Triple-Negative Breast ...
arxiv
Molecular Imaging Provides Novel Insights on Estrogen Receptor Activity in Mouse Brain
Molecular Imaging, 2008 Estrogen receptors have long been known to be expressed in several brain areas in addition to those directly involved in the control of reproductive functions.
Alessia Stell +3 more
doaj +1 more source
Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line
Research in Pharmaceutical Sciences, 2018 Estrogen is a steroid hormone that plays a key role in the development and regulation of reproductive system. It has been shown that estrogen is related to breast cancer development through binding to its receptors.
Azam Mohamadi +2 more
doaj +1 more source
Sparse quadratic classification rules via linear dimension reduction [PDF]
Journal of Multivariate Analysis 2019, Vol. 169, 278-299, 2017 We consider the problem of high-dimensional classification between the two groups with unequal covariance matrices. Rather than estimating the full quadratic discriminant rule, we propose to perform simultaneous variable selection and linear dimension reduction on original data, with the subsequent application of quadratic discriminant analysis on the ...
arxiv +1 more source
Silibinin protects GLUTag cells from PA-induced injury via suppressing endoplasmic reticulum stress
CyTA - Journal of Food, 2023 Silibinin is a natural flavonoid with anti-diabetic activity. Glucagon-like peptide−1 (GLP−1), an intestinal hormone mainly secreted from L cells, which regulates insulin production and sensitivity, appears to be a potential therapeutic strategy for T2DM.
Xinyi Shi +9 more
doaj +1 more source
Archives of Pathology & Laboratory Medicine, 2011 Abstract Context—A new class of estrogen receptors was discovered in 1996 and named estrogen receptor β (ER-B); the traditional estrogen receptor, which until a little more than 10 years ago was thought of as the only estrogen receptor in existence, is now called estrogen receptor α. Estrogen receptor β has at least 5 isoforms, which may
Mamoun Younes, Naoko Honma
openaire +3 more sources
Neuroprotection and Estrogen Receptors [PDF]
Neuroendocrinology, 2012 This review is intended to assess the state of current knowledge on the role of estrogen receptors (ERs) in the neuroprotective effects of estrogens in models for acute neuronal injury and death. We evaluate the overall evidence that estrogens are neuroprotective in acute injury and critically assess the role of ERα, ERβ, GPR 30, and nonreceptor ...
Anne M. Etgen +3 more
openaire +3 more sources