Results 41 to 50 of about 2,636,320 (328)
The Role of Estrogen Receptors in Urothelial Cancer
Frontiers in Endocrinology, 2021 Epidemiological data have indicated that there are some sex-related differences in bladder cancer. Indeed, the incidence of bladder cancer in men has been substantially higher than that in women throughout the world, while women tend to have higher stage
Takuro Goto +4 more
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Estrogen Receptors: New Directions in the New Millennium.
Endocrine reviews, 2018 Nineteen years have passed since our previous review in this journal in 1999 regarding estrogen receptors. At that time, we described the current assessments of the physiological activities of estrogen and estrogen receptors.
S. Hewitt, K. Korach
semanticscholar +1 more source
Epigenetics and the Estrogen Receptor
Annals of the New York Academy of Sciences, 2006 Abstract: The position effect variegation in Drosophila and Schizosaccharomyces pombe, and higher‐order chromatin structure regulation in yeast, is orchestrated by modifier genes of the Su(var) group, (e.g., histone deacetylases ([HDACs]), protein phosphatases) and enhancer E(Var) group (e.g., ATP [adenosine 5′‐triphosphate]‐dependent nucleosome ...
Richard G. Pestell +5 more
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Estrogen Receptors in the Male [PDF]
Archives of Andrology, 1981 Estrogens in the male are secreted by the testes and derived extragonadally from the aromatization of certain androgens. In some brain regions critical for the control of gonadotropin secretion and behavior, androgens may be aromatized to estrogens within the cells that are regulated. Estrogen may have other physiological roles on the testes to control
C. R. Clark, R. B. Dickson
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Targeting mutant estrogen receptors
eLife, 2019 A drug used in hormone replacement therapy can target estrogen receptors that have become resistant to breast cancer treatments.
Suzanne E Wardell +2 more
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Insights from the Structure of Estrogen Receptor into the Evolution of Estrogens: Implications for Endocrine Disruption [PDF]
, 2011 In the last decade, there has been important progress in understanding the origins and evolution of receptors for adrenal steroids (aldosterone, cortisol) and sex steroids (estradiol, progesterone, testosterone) due to the sequencing of genomes from ...
Michael E. Baker
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Endometrial Progesterone and Estrogen Receptors in Relation to Hormonal Levels in Women with Unexplained Recurrent Miscarriage [PDF]
Revista Brasileira de Ginecologia e Obstetrícia, 2023 Objective Recurrent miscarriage has been linked to hormonal disturbance due to dysregulation of its receptors rather than to the availability of the hormone.
Ihab Adel Gomaa +4 more
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Phytochemicals Targeting Estrogen Receptors: Beneficial Rather Than Adverse Effects?
International Journal of Molecular Sciences, 2017 In mammals, the effects of estrogen are mainly mediated by two different estrogen receptors, ERα and ERβ. These proteins are members of the nuclear receptor family, characterized by distinct structural and functional domains, and participate in the ...
S. Lecomte +3 more
semanticscholar +1 more source
Estrous behavior in dairy cows: identification of underlying mechanisms and gene functions [PDF]
, 2010 Selection in dairy cattle for a higher milk yield has coincided with declined fertility. One of the factors is reduced expression of estrous behavior. Changes in systems that regulate the estrous behavior could be manifested by altered gene expression ...
Beerda, B. +3 more
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The binding of estrogen and estrogen antagonists to the estrogen receptor
Archives of Biochemistry and Biophysics, 1992 The model of the estrogen receptor as a dimer of identical, interacting subunits and data obtained by Sasson and Notides (1988, Mol. Endocrinol. 2, 307-312) were used to find the standard free energy changes that describe the binding of estradiol and 4-hydroxytamoxifen to the estrogen receptor.
Shlomo Sasson +2 more
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