Results 41 to 50 of about 264,406 (266)

Molecular Imaging Provides Novel Insights on Estrogen Receptor Activity in Mouse Brain

Molecular Imaging, 2008
Estrogen receptors have long been known to be expressed in several brain areas in addition to those directly involved in the control of reproductive functions.
Alessia Stell, Silvia Belcredito, Paolo Ciana, Adriana Maggi   +3 more
doaj   +1 more source

Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line

Research in Pharmaceutical Sciences, 2018
Estrogen is a steroid hormone that plays a key role in the development and regulation of reproductive system. It has been shown that estrogen is related to breast cancer development through binding to its receptors.
Azam Mohamadi, Mahmoud Aghaei, Mojtaba Panjehpour   +2 more
doaj   +1 more source

The steroid hormone estriol (E3) regulates epigenetic programming of fetal mouse brain and reproductive tract

BMC Biology, 2022
Background Estriol (E3) is a steroid hormone formed only during pregnancy in primates including humans. Although E3 is synthesized at large amounts through a complex pathway involving the fetus and placenta, it is not required for the maintenance of ...
Yuping Zhou, Baoxia Gu, Geraldine Brichant, Jay Prakash Singh, Huan Yang, Hao Chang, Yanding Zhao, Chao Cheng, Zhong-Wu Liu, Myles H. Alderman, Lingeng Lu, Xiaoyong Yang, Xiao-Bing Gao, Hugh S. Taylor   +13 more
doaj   +1 more source

Estradiol and testosterone levels in patients undergoing partial hepatectomy - A possible signal for hepatic regeneration? [PDF]

, 1989
In five adult male patients undergoing a 40-60% partial hepatectomy, serum sex hormone levels before and after hepatic resection were determined. Blood was drawn immediately prior to each surgical procedure and at specified time points postoperatively ...
A Francavilla, A Francavilla, A Francavilla, A Francavilla, B Fisher, B Saint Aubert, C Majumdar, CS Song, DH Marshall, FL Moolten, HL Leffert, I Seidman, IF Turocy, J Menard, J Simck, J Simck, JA Caruana, JC Davis, JH Laragh, K Sakuma, KH Raab, LE Porter, MJ Duffy, NLR Bucher, NLR Bucher, P Bannister, P Vic, PK Eagon, PK Eagon, PL Corvol, RA Richman, RF Aten, S Bengmark, S Bengmark, W Powell-Jones   +34 more
core   +2 more sources

Estrogen modulation of pain perception with a novel 17β-estradiol pretreatment regime in ovariectomized rats

Biology of Sex Differences, 2020
Estrogen plays substantial roles in pain modulation; however, studies concerning sex hormones and nociception often yield confusing results. The discrepancy could be a result of lack of consensus to regard estrogen as a variable when working with animal ...
Wenxin Zhang, Hui Wu, Qi Xu, Sheng Chen, Lihong Sun, Cuicui Jiao, Luyang Wang, Feng Fu, Ying Feng, Xiaowei Qian, Xinzhong Chen   +10 more
doaj   +1 more source

Estrogen metabolism: why it’s so crucial to keep the balance?

Гинекология, 2020
Aim. To analyze and systematize the available information on pathogenetic mechanisms of hormonal carcinogenesis. Materials and methods. The review includes data from foreign articles published in PubMed and Medline and national works posted on ...
Oksana V. Yakushevskaya, Svetlana V. Yureneva, Anna E. Protasova   +2 more
doaj   +1 more source

Silibinin protects GLUTag cells from PA-induced injury via suppressing endoplasmic reticulum stress

CyTA - Journal of Food, 2023
Silibinin is a natural flavonoid with anti-diabetic activity. Glucagon-like peptide−1 (GLP−1), an intestinal hormone mainly secreted from L cells, which regulates insulin production and sensitivity, appears to be a potential therapeutic strategy for T2DM.
Xinyi Shi, Chun Chu, Xiang Li, Luxin Zhang, Xiaorong Zhang, Na Chen, Weiwei Liu, Zixuan Jiao, Takashi Ikejima, Fanxing Xu   +9 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Trichoplax, the simplest known animal, contains an estrogen-related receptor: Implications for the evolution of vertebrate and invertebrate estrogen receptors [PDF]

, 2008
Although, as their names imply, vertebrate and invertebrate estrogen receptors [ERs] and estrogen-related receptors [ERRs] are related transcription factors, their evolutionary relationships to each other are not fully understood.
Michael E. Baker
core   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source