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Local estrogen formation and its regulation in endometriosis
Background It has been well established that endometriosis is an estrogen‐dependent disease. Although the exact pathogenesis of the disease is still unclear, it is known to be characterized by estrogen‐dependent growth and maintenance of the ectopic ...
Taisuke Mori+7 more
doaj +1 more source
Ageing And Cancer As Diseases Of Epigenesis [PDF]
Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
core +2 more sources
Effect of cyclosporine on hepatic cytosolic estrogen and androgen receptor levels before and after partial hepatectomy [PDF]
Estrogen and androgen receptors within the liver have been reported to modulate the hepatic regenerative response to partial hepatectomy. Moreover, cyclosporine has several untoward effects that might occur as a consequence of alterations in sex hormone ...
A Francavilla+33 more
core +1 more source
Duplicated membrane estrogen receptors in the European sea bass (Dicentrarchus labrax): Phylogeny, expression and regulation throughout the reproductive cycle [PDF]
The numerous estrogen functions reported across vertebrates have been classically explained by their binding to specific transcription factors, the nuclear estrogen receptors (ERs).
Alvarado, M. Victoria+5 more
core +1 more source
Molecular Imaging Provides Novel Insights on Estrogen Receptor Activity in Mouse Brain
Estrogen receptors have long been known to be expressed in several brain areas in addition to those directly involved in the control of reproductive functions.
Alessia Stell+3 more
doaj +1 more source
Estrogen stimulates adenosine receptor expression subtypes in human breast cancer MCF-7 cell line
Estrogen is a steroid hormone that plays a key role in the development and regulation of reproductive system. It has been shown that estrogen is related to breast cancer development through binding to its receptors.
Azam Mohamadi+2 more
doaj +1 more source
Triple negative breast cancer: new perspectives for targeted therapies [PDF]
Breast cancer is a heterogeneous disease, encompassing a large number of entities showing different morphological features and having clinical behaviors.
Caruso, Davide+8 more
core +1 more source
Estrogen plays substantial roles in pain modulation; however, studies concerning sex hormones and nociception often yield confusing results. The discrepancy could be a result of lack of consensus to regard estrogen as a variable when working with animal ...
Wenxin Zhang+10 more
doaj +1 more source
The transcriptional coactivator PPARγ coactivator-1α (PGC-1α) has been characterized as a broad regulator of cellular energy metabolism. Although PGC-1α functions through many transcription factors, the PGC-1α partners identified to date are unlikely to ...
J. Huss, R. Kopp, D. Kelly
semanticscholar +1 more source
Nuclear receptors in vascular biology [PDF]
Nuclear receptors sense a wide range of steroids and hormones (estrogens, progesterone, androgens, glucocorticoid, and mineralocorticoid), vitamins (A and D), lipid metabolites, carbohydrates, and xenobiotics.
A Chawla+56 more
core +2 more sources