Results 61 to 70 of about 256,632 (314)

Purified and specific cytoplasmic pollen extract: a non-hormonal alternative for the treatment of menopausal symptoms. [PDF]

, 2020
Research into non-hormonal, alternative therapies is necessary for women for whom menopausal hormone therapy is contraindicated or for women who do not wish to take hormones.
Biglia, Nicoletta, Birkhaeuser, Martin, Brincat, Mark, Celis-Gonzales, Cuauhtémoc, Depypere, Herman, Egarter, Christian, Fait, Tomas, Genazzani, Andrea, Goldstein, Steven, Mueck, Alfred, Palacios, Santiago, Panay, Nick, Ruan, Xiangyan, Simoncini, Tommaso, Skouby, Sven O   +14 more
core   +4 more sources

The estrogen receptor and metabolism

Women's Health
Across the globe, metabolic syndrome, hyperuric acid, and their related diseases, such as cardiovascular disease, diabetes, and insulin resistance, are increasing in incidence due to metabolic imbalances. Due to the pathogenesis, women are more prone to these diseases than men.
Zizi Xiao, Haijun Liu
openaire   +3 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Expression of estrogen and progesterone receptors in astrocytomas: a literature review

Clinics
Gliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones.
Cléciton Braga Tavares, Francisca das Chagas Sheyla Almeida Gomes-Braga, Danylo Rafhael Costa-Silva, Carla Solange Escórcio-Dourado, Umbelina Soares Borges, Airton Mendes Conde-Junior, Maria da Conceição Barros-Oliveira, Emerson Brandão Sousa, Lorena da Rocha Barros, Luana Mota Martins, Gil Facina, Benedito Borges da-Silva   +11 more
doaj   +1 more source

Estrogen-Related Receptors in Breast Cancer and Prostate Cancer

Frontiers in Endocrinology, 2015
Estrogen signaling pathways are implicated in the development of breast cancer and prostate cancer. Various studies have focused on additional signaling pathways, mediated by estrogen-related receptors (ERRs).
Satoshi eInoue, Satoshi eInoue, Aya eMisawa   +2 more
doaj   +1 more source

Gene Expression and the Physiological Role of Transforming Growth Factor-α in the Mouse Pituitary [PDF]

, 2003
Transforming growth factor-alpha (TGF-alpha), a member of the epidermal growth factor (EGF) family, is produced within the mouse anterior pituitaries. However, the cell types of TGF-alpha-expressing cells and the physiological roles of TGF-a within mouse
Kakeya, Tomoshi, Masui, Tohru, Oomizu, Souichi, Sharma, Seema, Takahashi, Sumio, Takeuchi, Sakae   +5 more
core   +1 more source

Estrogen-Independent Activation of Estrogen Receptors [PDF]

Hypertension, 2011
See related article, pp 1161–1166 Sex differences showing a lower prevalence and better outcome after ischemic stroke in women have been described, differences that are abrogated by natural or surgical menopause.1,2 High levels of endogenous estrogens in premenopausal women have been associated with reduced risk for a number of diseases, such as ...
Matthias R. Meyer, Matthias Barton, Eric R. Prossnitz   +2 more
openaire   +3 more sources

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

Estrogen Actions in Triple-Negative Breast Cancer

Cells, 2020
Triple-negative breast cancer (TNBC) lacks estrogen receptor (ER) α, but the expression of estrogen receptors ERβ and G protein-coupled estrogen receptor 1 (GPER-1) is able to trigger estrogen-responsivity in TNBC.
Oliver Treeck, Susanne Schüler-Toprak, Olaf Ortmann   +2 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source