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Ubiquitination of G-Protein-Coupled Receptors
2004In this chapter we describe methods for detecting the ubiquitination state of G-protein-coupled receptors (GPCRs). This involves coexpression of a GPCR with an epitope-tagged ubiquitin construct in a heterologous expression system. Modification by ubiquitin of the GPCR resulting from agonist activation is detected by immunoprecipation and subsequent ...
Adriano, Marchese, Jeffrey L, Benovic
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Molecular signatures of G-protein-coupled receptors
Nature, 2013A. Venkatakrishnan +6 more
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Adrenergic Receptors As Models For G Protein-Coupled Receptors
Annual Review of Neuroscience, 1992Approximately 80% of known hormones and neurotransmitters activate cellular signal transduction mechanisms by activating G protein-coupled receptors (Birnbaumer et al 1990). Studying the structure and function of these receptors has been challenging because they are not naturally abun dant proteins and they require a lipid environment to be fully ...
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Crystal Structure of Rhodopsin: A G‐Protein‐Coupled Receptor
ChemBioChem, 2002R. Stenkamp, D. Teller, K. Palczewski
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Mechanisms of signalling and biased agonism in G protein-coupled receptors
Nature reviews. Molecular cell biology, 2018D. Wootten +6 more
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G-protein-coupled receptor websites
Trends in Pharmacological Sciences, 2002Brinda K, Rana, Paul A, Insel
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