Results 221 to 230 of about 162,039 (295)

Computational Neuroscience's Influence on Autism Neuro-Transmission Research: Mapping Serotonin, Dopamine, GABA, and Glutamate. [PDF]

Biomedicines
Bamicha V, Pergantis P, Skianis C, Drigas A.   +3 more
europepmc   +1 more source

Patient‐Derived Cortical Organoids Reveal Senescence of Neural Progenitor Cells in Hutchinson‐Gilford Progeria Syndrome

Aging Cell, EarlyView.
HGPS patient‐derived cortical organoids exhibit progerin accumulation, nuclear abnormalities, and increased senescence in rosette structures, leading to impaired neuronal differentiation and altered gene expression. ABSTRACT Hutchinson‐Gilford progeria syndrome (HGPS) is a rare genetic disorder characterized by premature aging and primarily caused by ...
Seeun Jeon, Chul‐Sung Park, Juyoung Hong, Jieun Kim, Yun Jin Lee, Junho K. Hur, Ji Yeoun Lee   +6 more
wiley   +1 more source

Altered activity within the social behavior neural network in adolescent rats following prenatal alcohol exposure and/or early‐life adversity

Alcohol, Clinical and Experimental Research, EarlyView.
Prenatal alcohol exposure (PAE) and early‐life adversity (ELA) independently and interactively disrupted neural activity within the social behavior network in adolescent rats, with age‐ and sex‐specific effects. PAE primarily dampened amygdala activity, while ELA altered medial prefrontal cortex responses. These findings reveal how different early‐life
Parker J. Holman, Linda Ellis, Amanda Chao, Cecilia Mitchell, Charlis Raineki, Joanne Weinberg   +5 more
wiley   +1 more source

Curcumin reduces pain after spinal cord injury in rats by decreasing oxidative stress and increasing GABAA receptor and GAD65 levels. [PDF]

Sci Rep
Hadadi M, Farazi MM, Mehrabani M, Tashakori-Miyanroudi M, Behroozi Z.   +4 more
europepmc   +1 more source

Chronic intermittent alcohol yields sex‐specific disruptions in cortical‐striatal‐limbic oscillations in rats

Alcohol, Clinical and Experimental Research, EarlyView.
This study shows that chronic alcohol exposure leads to sex‐specific disruptions in local field potentials, specifically causing changes to amygdala oscillations in females and prefrontal cortical and nucleus accumbens oscillations in males. These data may explain some of the sex differences observed in alcohol misuse and provide potential biomarkers ...
Kelly A. Hewitt, Skylar E. Nicholson, Madilyn J. Peterson, Lucas L. Dwiel, Angela M. Henricks   +4 more
wiley   +1 more source

Proteomic Learning of Gamma-Aminobutyric Acid (GABA) Receptor-Mediated Anesthesia. [PDF]

J Chem Inf Model
Jiang J, Chen L, Zhu Y, Shi Y, Qiu H, Zhang B, Zhou T, Wei GW.   +7 more
europepmc   +1 more source

La femme fait la maison: The Accumulation of Surplus Value through Family Planning in Burkina Faso1

Antipode, EarlyView.
Abstract Since the 1960s, demographers, international donors, and governments have calculated the political, economic, and social benefits of modern contraception usage in West Africa. We evidence how family planning technologies (FPTs) that are tethered to population development extract double value (productive and reproductive labour) from Burkinabè ...
T.D. Harper‐Shipman, Katian Napon
wiley   +1 more source

Molecular Basis of Anxiety: A Comprehensive Review of 2014-2024 Clinical and Preclinical Studies. [PDF]

Int J Mol Sci
Merkouris E, Brasinika A, Patsiavoura M, Siniosoglou C, Tsiptsios D, Triantafyllis AS, Mueller C, Mpikou I, Samara MT, Christodoulou N, Tsamakis K.   +10 more
europepmc   +1 more source

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

Acta Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs, Berith M. Balfoort, Marion M. Brands, Anneloor L. M. A. ten Asbroek, Camiel J. F. Boon, Roselie M. H. Diederen, Corrie Timmer, Margreet A. E. M. Wagenmakers, Hans R. Waterham, Ronald J. A. Wanders, Riekelt H. Houtkooper, Clara D. van Karnebeek, Arthur A. Bergen   +12 more
wiley   +1 more source

Local Regulation of Striatal Dopamine Release Shifts from Predominantly Cholinergic in Mice to GABAergic in Macaques. [PDF]

J Neurosci
Shin JH, Goldbach HC, Burke DA, Authement ME, Swanson ES, Bocarsly ME, Hernandez S, Kwon HB, Cerveny SE, Mehr JB, Plotnikova AS, Mohanty A, Cummins AC, Pelkey KA, McBain CJ, Khaliq ZM, Eldridge MAG, Averbeck BB, Alvarez VA.   +18 more
europepmc   +1 more source