Results 221 to 230 of about 604,542 (323)

Evaluation of the Sedative Activity of Naringenin: In Vivo Study with Pharmacokinetics and Molecular Docking Insights

ChemistryOpen, EarlyView.
The study investigates the sedative potential of naringenin (NAR) through in vivo and in silico approaches. NAR significantly enhances sleep duration and reduces latency in mice, especially when combined with diazepam. Molecular docking shows strong binding to GABAA receptors, suggesting a GABAergic mechanism.
Dipu Bishwas, Md. Shimul Bhuia, Salehin Sheikh, Mohammed Alfaifi, Abdul Malik, Nikhat J. Siddiqui, Divya Jain, Mehedi Hasan Bappi, Muhammad Torequl Islam   +8 more
wiley   +1 more source

Cancer and neurotransmitter receptors. [PDF]

Chin Med J (Engl)
Wang X, Shi M, Tian J, Yu W.
europepmc   +1 more source

Fecal Metaproteomics as a Tool to Monitor Functional Modifications Induced in the Gut Microbiota by Ketogenic Diet: A Case Study

PROTEOMICS, EarlyView.
ABSTRACT Metaproteomics is a valuable approach to characterize the biological functions involved in the gut microbiota (GM) response to dietary interventions. Ketogenic diets (KDs) are very effective in controlling seizure severity and frequency in drug‐resistant epilepsy (DRE) and in the weight loss management in obese/overweight individuals.
Alessandro Tanca, Simona Masia, Piero Giustacchini, Sergio Uzzau   +3 more
wiley   +1 more source

SKF-38393 regulates the expression of glutamic acid decarboxylase 67 via heparanase-1 in 6-hydroxydopamine-induced neurodegeneration. [PDF]

Sci Rep
Lee S, Kim M, Sung SE, Kim G, Won C.
europepmc   +1 more source

The continuing significance of chiral agrochemicals

Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.
In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley   +1 more source

Ketamine in Status Epilepticus: How Soon Is Now? [PDF]

Neurol Int
Magro G.
europepmc   +1 more source

Decision‐making in entrepreneurial teams with competing economic and noneconomic goals

Strategic Entrepreneurship Journal, EarlyView.
Abstract Research Summary How should decision‐making be organized in entrepreneurial teams pursuing competing economic and noneconomic goals? Using a computational model, we examine how four archetypical decision‐making structures—unanimous approval, individual autonomy, majority voting, and lead entrepreneur—shape the performance of entrepreneurial ...
Jeroen Neckebrouck, Thomas Zellweger
wiley   +1 more source

GABA and Octopamine Receptors as Potential Targets for Fumigant Actions of <i>Bursera graveolens</i> Essential Oil Against <i>Callosobruchus maculatus</i> and <i>Callosobruchus chinensis</i>. [PDF]

J Xenobiot
Viteri LO, González MJ, Silva PB, Gomes JM, Svacina T, Costa LTM, Valarezo E, Mantilla-Afanador JG, Herrera OM, Aguiar RWS, Santos GR, Oliveira EE.   +11 more
europepmc   +1 more source

Neural circuitry of rapid eye movement sleep homeostasis: Mechanistic insights and pathological implications

Sleep Research, EarlyView.
Abstract Rapid eye movement (REM) sleep is a unique brain state crucial for emotion, memory, and plasticity. Unlike well‐understood non‐REM (NREM) sleep homeostasis, REM sleep homeostasis remains less clearly defined. This review highlights recent progress in understanding REM sleep homeostasis, focusing on its neurophysiological markers, neural ...
Ting He
wiley   +1 more source

Regulatory effects of head acupuncture on the GABAergic system and Wnt7a/β-catenin pathway in post-stroke spasticity rats. [PDF]

J Mol Histol
Kang X, Chen S, Ma L, Kong Y, Huang Y, Shi S.   +5 more
europepmc   +1 more source