Neurotransmitter-Mediated Signaling in Glioblastoma and Glial Tumors: Biology and Therapeutic Opportunities. [PDF]
Tralongo P +11 more
europepmc +1 more source
Maternal and infant gut microbiome
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang +25 more
wiley +1 more source
Artificial intelligence in the assessment of epilepsy-related genetic mutations: Learned from GABA<sub>A</sub> receptors and GABA transporter 1. [PDF]
Wang J, Kang JQ.
europepmc +1 more source
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li +29 more
wiley +1 more source
GABA-Producing Bacteria as Potential Psychobiotics in Gut-Brain Axis Regulation. [PDF]
Zielińska E +4 more
europepmc +1 more source
Reversing brain aging: Targeting energy metabolism in endogenous neural stem cells
Mechanism of endogenous neural stem cells (eNSCs) energy metabolism disorder leading to brain aging and targeted eNSCs intervention strategies (By biorender). The disorder of energy metabolism of eNSCs can lead to their resting and aging, and eventually lead to brain aging.
Chong Chen +6 more
wiley +1 more source
GABA-mediated regulation of lipid metabolism: a conserved relation with diverse physiological significances. [PDF]
Pradhan S +4 more
europepmc +1 more source
ABSTRACT Background Claustrophobia during MRI may lead to examination interruption, motion artifacts, prolonged acquisition time, and reduced diagnostic quality, frequently requiring intravenous sedation to ensure successful examination completion and adequate image acquisition.
Beatriz Birelli do Nascimento +5 more
wiley +1 more source
A malignant symbiosis: The neuro-metabolic symphony rewires the tumor microenvironment. [PDF]
Zhang Z, Jia Y, Liu T, Wang S, Liu L.
europepmc +1 more source
Alterations in brain metabolites in rats with experimental periodontitis: A metabolomic approach
Abstract Background Periodontitis (PD) is a chronic inflammatory disease with systemic effects. Emerging evidence suggests a link between periodontal inflammation and neurological changes, but the biochemical mechanisms in key brain regions, such as the hippocampus and amygdala, remain unclear.
Ramona Ramalho de Souza Pereira +9 more
wiley +1 more source

