Results 191 to 200 of about 617,141 (296)

Emerging role of GLP-1 mono, dual, and triple agonists in the management of MASH-related fibrosis. [PDF]

Cell Rep Med
Tavaglione F, Loomba R.
europepmc   +1 more source

Multifaceted burden of short bowel syndrome for patients and caregivers: The landmark survey

Nutrition in Clinical Practice, EarlyView.
Abstract Background Short bowel syndrome is a debilitating condition often requiring long‐term parenteral support to maintain hydration, nutrition, and survival. Methods As part of the noninterventional, cross‐sectional Landmark Survey study, we evaluated burdens associated with short bowel syndrome and parenteral support dependency from patient and ...
Jenny E. Harrison, Syed‐Mohammed Jafri, Roopa Vemulapalli, Vanessa Kumpf, Gail Mitchell, Mena Boules, Mindy M. Yang, Laurin Jackson, Jinyi Wang, Laurie Zografos, Daniel Wolin, Marion F. Winkler   +11 more
wiley   +1 more source

The Evolution of Medications for Obesity Management. [PDF]

JGH Open
Gill J, Sumithran P.
europepmc   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

Targeting glucagon signaling in metabolic disorders, functional insights from zebrafish receptor knockouts. [PDF]

Cell Mol Life Sci
Al Madhoun A, Malik MZ, Al-Beloushi S, Abukhalaf N, Miranda L, Jacob S, Nizam R, John S, George P, Channanath A, Bahman F, Liao M, Ahmad R, Chen W, Bekri A, Drapeau P, Thanaraj TA, Al-Mulla F.   +17 more
europepmc   +1 more source

How the Sea Salt Chocolate Cookie Became a Thing: The Role of Flavor Pairing in Obesity

Obesity, EarlyView.
Proposed framework illustrating how flavor pairing and multisensory flavor architecture may sustain hedonic eating through enhanced palatability, reward preservation, delayed sensory‐specific satiety, and post‐ingestive signaling, thereby promoting excess energy intake and obesity risk.
Mohammed Ayyad, Eugene Kim
wiley   +1 more source

The evolving therapeutic landscape of gut-pancreatic peptide signalling in metabolic disorders: from mono- to multi-agonist therapies. [PDF]

Biosci Rep
Patil M, Piccinini F, Johnstone EKM, Casari I, Falasca M.   +4 more
europepmc   +1 more source

Glucagon Receptor Binding [PDF]

, 2020
openaire   +1 more source

Incidental Resolution of Dopamine Agonist Induced Impulse Control Disorder with GLP‐1 Receptor Agonist

Movement Disorders Clinical Practice, EarlyView.
Hannah Kelly, Thomas Davis
wiley   +1 more source

Incretin‐Based Therapies: A Testable Hypothesis Linking Incretin Signaling, Mitochondrial Redox, and OXPHOS Efficiency

Obesity, EarlyView.
ABSTRACT Objective Incretin‐based obesity therapies (IBTs), especially GLP‐1 receptor agonists (GLP‐1 RAs), effectively treat obesity and improve comorbidities. However, their impact on energy metabolism is unclear. A recent case of acute generalized muscle weakness in a patient with mitochondrial myopathy after tirzepatide exposure raises concerns ...
Bryn Falahee, Caroline M. Apovian, Nawfal Istfan   +2 more
wiley   +1 more source