Obesity pharmacotherapy reimagined: The era of multi-receptor agonists and next-generation metabolic modulators, perspectives and controversies. [PDF]
Metabol OpenLempesis IG, Dalamaga M.
europepmc +1 more source
Can Reprogramming Taste Modulate Excess Food Intake?
Obesity, EarlyView.
Kerstin Rohde‐Zimmermann +1 more
wiley +1 more source
AlphaFold2‐Guided Cyclic Peptide Stabilizer Design to Target Protein–Protein Interactions
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The control and modulation of protein–protein interactions (PPIs) is of central importance for the majority of biological processes and most biomedical applications. Stabilization of PPIs, besides inhibition, is of growing pharmaceutical interest.
Niklas Halbwedl, Martin Zacharias
wiley +1 more source
The Interplay Between GLP-1-Based Therapies, the Gut Microbiome, and MASLD/MASH in Type 2 Diabetes Mellitus: A Narrative Review. [PDF]
BiomedicinesDinkov B, Pendicheva-Duhlenska D.
europepmc +1 more source
Staging concept for aging management: Definition, mechanism, and coping strategies
VIEW, EarlyView.We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang +6 more
wiley +1 more source
IUPHAR review: From foe to friend: Repurposing glucagon to treat obesity and type 2 diabetes. [PDF]
Pharmacol ResElmendorf AJ +5 more
europepmc +1 more source
How Changing Food Preferences and Technology Are Transforming Food Markets
Journal of Agricultural Economics, EarlyView.ABSTRACT The foods that consumers purchase and how they purchase food are changing over time. In this article, we discuss how health prioritization and environmental concerns, combined with new technologies, are changing consumers' food preferences and retail choices.
Jill J. McCluskey, Jillian Hyink
wiley +1 more source
Functional Divergence of <i>adcyap1b</i> Splice Variants in Regulating Pituitary Hormone Expression in the Chinese Tongue Sole (<i>Cynoglossus semilaevis</i>). [PDF]
Int J Mol SciZhang Q +7 more
europepmc +1 more source
Adaptation of the invasive pest Drosophila suzukii to a specialized nutritional niche
Insect Science, EarlyView.Unlike most Drosophila larvae that feed on spoiled food, Drosophila suzukii larvae thrive on ripening fruits and consequently face a low‐protein, high‐carbohydrate nutritional challenge. Comparisons of growth among D. suzukii, D. biarmipes, and D. melanogaster larvae across diets with varying protein‐to‐carbohydrate ratios demonstrate that D.
Yan Hou, Ying Zhen
wiley +1 more source