Results 191 to 200 of about 618,319 (304)

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

Silver Nanoparticles Attenuate Histamine-Induced Pruritus via Modulation of the Nitric Oxide/iNOS Signaling Pathway in Mice. [PDF]

Nanotechnol Sci Appl
Bayan AM, Khan MI.
europepmc   +1 more source

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source

Is histamine intolerance a treatable subtype of fibromyalgia? evidence and clinical implications-narrative review. [PDF]

Front Pain Res (Lausanne)
Protásio Netto J, Lana JF, Parma A, Costa FR, de Andrade RM, Castro MGM, Tambelli C.   +6 more
europepmc   +1 more source

The ongoing oleoylethanolamide story: Therapeutic implications in the control of obesity and its comorbidities

British Journal of Pharmacology, EarlyView.
The global burden of obesity continues to rise, demanding effective pharmacological strategies for individuals in whom prevention alone is insufficient. Recent incretin‐based and multi‐agonist therapies have delivered unprecedented weight loss, demonstrating that the simultaneous modulation of multiple metabolic pathways can optimize body weight ...
Marzia Friuli, Alessia Campagna, Barbara Eramo, Christian Sepe, Annarita Zuena, Silvana Gaetani, Adele Romano   +6 more
wiley   +1 more source

Atopic dermatitis: pathogenesis, immunology, microbiome, and salivary biomarkers. [PDF]

Front Immunol
Abraityte S, Tamasauskiene L, Gasiuniene E, Jankauskaite L.   +3 more
europepmc   +1 more source

Involvement of histamine H1 and H4 receptors in a murine model of acute skin inflammation and pruritus

, 2014
GRANDI, Daniela, ADAMI, Maristella, MICHELONI, Cristina, CORUZZI, Gabriella, PELLACANI, Claudia   +4 more
core  

Histamine in Diabetic Cardiovascular Complications. [PDF]

Rev Cardiovasc Med
Hu S, Zeng G, Tang Y, Wang Q, Wu J, Yang X.   +5 more
europepmc   +1 more source

Suicidality associated with betahistine: A rare case report and systematic review of histaminergic drug-induced depression. [PDF]

Medicine (Baltimore)
Tang J, Zeng Y, Jiang X.
europepmc   +1 more source

Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use—A Scoping Review

Clinical &Experimental Allergy, EarlyView.
Rebound pruritus and urticaria have been reported after discontinuation of chronic cetirizine or levocetirizine use only. Symptoms typically occur within 0.5–5 days after stopping therapy and appear more frequently reported in female patients. Re‐initiation of antihistamines is the most commonly effective management strategy, highlighting the need for ...
Jun Jie Benjamin Seng, Prawira Oka, Ngiap Chuan Tan   +2 more
wiley   +1 more source