Results 21 to 30 of about 49,569 (265)

Votucalis, a Novel Centrally Sparing Histamine-Binding Protein, Attenuates Histaminergic Itch and Neuropathic Pain in Mice

open access: yesFrontiers in Pharmacology, 2022
Votucalis is a biologically active protein in tick (R. appendiculatus) saliva, which specifically binds histamine with high affinity and, therefore, has the potential to inhibit the host’s immunological responses at the feeding site. We hypothesized that
Ibrahim Alrashdi   +12 more
doaj   +1 more source

Histamine, histamine receptors, and neuropathic pain relief [PDF]

open access: yesBritish Journal of Pharmacology, 2019
Histamine, acting via distinct histamine H1, H2, H3, and H4 receptors, regulates various physiological and pathological processes, including pain. In the last two decades, there has been a particular increase in evidence to support the involvement of H3 receptor and H4 receptor in the modulation of neuropathic pain, which remains challenging in terms ...
Ilona Obara   +3 more
openaire   +4 more sources

Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]

open access: yesArchives of Razi Institute, 2022
The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar   +3 more
doaj   +1 more source

Molecular Modeling of Histamine Receptors—Recent Advances in Drug Discovery

open access: yesMolecules, 2021
The recent developments of fast reliable docking, virtual screening and other algorithms gave rise to discovery of many novel ligands of histamine receptors that could be used for treatment of allergic inflammatory disorders, central nervous system ...
Pakhuri Mehta   +2 more
doaj   +1 more source

New Developments in the Use of Histamine and Histamine Receptors [PDF]

open access: yesCurrent Allergy and Asthma Reports, 2010
Histamine and the histamine receptors are important regulators of a plethora of biological processes, including immediate hypersensitivity reactions and acid secretion in the stomach. In these roles, antihistamines have found widespread therapeutic applications, while the last receptor to be discovered, the H4 histamine receptor, has become a major ...
Craig, Smuda, Paul J, Bryce
openaire   +2 more sources

Functional Diversity of Histamine and Histamine Receptors

open access: yesJournal of Investigative Dermatology, 1992
In order to analyze the mechanisms by which a single biogenic amine like histamine is capable of inducing a wide variety of both physiologic and pathologic functions in various tissues/cells, histamine responses were dissected in detail from a biochemical and pharmacologic point of view.
Mitsuhashi, Masato, Payan, Donald G
openaire   +2 more sources

Effects of histamine on human periodontal ligament fibroblasts under simulated orthodontic pressure.

open access: yesPLoS ONE, 2020
As type-I-allergies show an increasing prevalence in the general populace, orthodontic patients may also be affected by histamine release during treatment.
Marcella Groeger   +6 more
doaj   +1 more source

Histamine and histamine receptors: Roles in major depressive disorder

open access: yesFrontiers in Psychiatry, 2022
Although the incidence of major depressive disorder (MDD) is high and its social impact is great, we still know very little about the pathophysiology of depression.
Hong Qian   +4 more
doaj   +1 more source

Recent Advances in Molecular Pharmacology of the Histamine Systems: Roles of C-terminal Tails of Histamine Receptors

open access: yesJournal of Pharmacological Sciences, 2006
.: G-protein-coupled receptors (GPCR) represent a large and diverse superfamily of integral membrane proteins to which histamine receptors belong. Increasing numbers of proteins have been identified to interact with the C-termini of GPCRs.
Kuramasu Atsuo   +3 more
doaj   +1 more source

Structural insights into the agonists binding and receptor selectivity of human histamine H4 receptor

open access: yesNature Communications, 2023
Histamine is a biogenic amine that participates in allergic and inflammatory processes by stimulating histamine receptors. The histamine H4 receptor (H4R) is a potential therapeutic target for chronic inflammatory diseases such as asthma and atopic ...
Dohyun Im   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy