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Matrix Metalloproteinases and Pro-Inflammatory Cytokines in Bladder Cancer: Diagnostic and Prognostic Perspectives: Narrative Review. [PDF]

Int J Mol Sci
Lipka U, Orywal K, Gudowska-Sawczuk M.
europepmc   +1 more source

Negative Regulator of Interferon Response Promotes Toll-like Receptor 3-induced Interleukin 6 in Rheumatoid Synoviocyte. [PDF]

In Vivo
Wada K, Imaizumi T, Ishibashi HK, Nakamura Y, Saruga T, Kawaguchi S, Tachizaki M, Oishi K, Sasaki E, Wada K, Ishibashi Y.   +10 more
europepmc   +1 more source

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Interleukin-10 and the Interleukin-10 Receptor

Annual Review of Immunology, 2001
Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on most hemopoietic cell types. The principal routine function of IL-10 appears to be to limit and ultimately terminate inflammatory responses.
K W, Moore, R, de Waal Malefyt, R L, Coffman, A, O'Garra   +3 more
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Interleukin-10 and Interleukin-10–Receptor Defects in Inflammatory Bowel Disease

Current Allergy and Asthma Reports, 2012
Inflammatory bowel disease (IBD) is a chronic inflammatory disease characterized by abdominal pain, bloody diarrhoea, and malabsorption leading to weight loss. It is considered the result of inadequate control of an excessive reaction of the immune system to the resident flora of the gut. Like other primary immunodeficiencies, IL-10 and IL-10 receptor (
Shah, Neil, Kammermeier, Jochen, Elawad, Mamoun, Glocker, Erik-Oliver   +3 more
openaire   +3 more sources

Role of interleukin-10 and interleukin-10 receptor in systemic lupus erythematosus

Clinical Rheumatology, 2013
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disease characterized by excessive production of a variety of autoantibodies, accumulation of immune complexes, and multiple organ systems involvement. Interleukin-10 (IL-10) has an important role in the growth, survival, differentiation, and function of B cells.
Hui, Peng, Wei, Wang, Mo, Zhou, Rui, Li, Hai-Feng, Pan, Dong-Qing, Ye   +5 more
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Expression and regulation of interleukin‐10 and interleukin‐10 receptor in rat astroglial and microglial cells

European Journal of Neuroscience, 2002
AbstractActivated glial cells crucially contribute to brain inflammatory responses. Interleukin‐10 (IL‐10) is an important modulator of glial cell responses in the brain. In the present study we describe the expression of IL‐10 and the IL‐10 receptor (IL‐10R1) in primary cocultures of rat microglial and astroglial cells.
Ledeboer, Annemarie, Brevé, John J P, Wierinckx, Anne, van der Jagt, Saskia, Bristow, Adrian F, Leysen, Josée E, Tilders, Fred J H, Van Dam, Anne-Marie   +7 more
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Interactions among the components of the interleukin-10 receptor complex

Biochemical and Biophysical Research Communications, 2006
We used fluorescence resonance energy transfer previously to show that the interferon-gamma (IFN-gamma) receptor complex is a preformed entity mediated by constitutive interactions between the IFN-gammaR2 and IFN-gammaR1 chains, and that this preassembled entity changes its structure after the treatment of cells with IFN-gamma.
Christopher D, Krause, Erwen, Mei, Olga, Mirochnitchenko, Natasha, Lavnikova, Junxia, Xie, Yiwei, Jia, Robin M, Hochstrasser, Sidney, Pestka   +7 more
openaire   +2 more sources