Results 231 to 240 of about 306,136 (269)

Purification of receptor complexes of interleukin‐10

European Journal of Biochemistry, 1999
Interleukin‐10 (IL‐10) is a pleiotropic immunosuppressive cytokine that has a wide range of effects in controlling inflammatory responses. Viral IL‐10 (vIL‐10) is a homologue of human IL‐10 (hIL‐10) produced by Epstein‐Barr virus (EBV). Both hIL‐10 and vIL‐10 bind to the soluble extracellular fragment of the cytokine receptor IL‐10R1 (shIL‐10R1).
D M, Hoover, C, Schalk-Hihi, C C, Chou, S, Menon, A, Wlodawer, A, Zdanov   +5 more
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Placental Tissue Interleukin‐10 Receptor Distribution in Pre‐eclampsia

American Journal of Reproductive Immunology, 2003
PROBLEM: Reduced placental (trophoblast) cytokine interleukin‐10 (IL‐10) occurs in human pre‐eclampsia. Along with an increase in inflammatory cytokines this may play an important role in the development of hypertension in pregnancy. It is not clear whether the changes in placental IL‐10 are due to a change in the placental cell production of IL‐10 or ...
Hennessy, Annemarie, Orange, Stefan, Painter, D. M., Horvath, John S.   +3 more
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Comparison of Interleukin-22 and Interleukin-10 Soluble Receptor Complexes

Journal of Interferon & Cytokine Research, 2002
Interleukin-22 (IL-22) is a cellular homolog of IL-10 that stimulates the production of acute-phase reactants. IL-22 and IL-10 require different ligand-specific receptor chains (IL-22R and IL-10R1) but share a second receptor chain (IL-10R2) to initiate cellular responses.
Naomi J, Logsdon, Brandi C, Jones, Kristopher, Josephson, Jennifer, Cook, Mark R, Walter   +4 more
openaire   +2 more sources

The human interleukin-10 receptor gene maps to chromosome 11q23.3

Human Genetics, 1995
The human interleukin-10 receptor (IL-10R) gene has previously been mapped to chromosome 11. Here, we have determined the precise location of the human IL-10R gene by the fluorescence in situ hybridization method, and have found that the IL-10R gene maps to chromosome 11q23.3.
T, Taniyama, S, Takai, E, Miyazaki, R, Fukumura, J, Sato, Y, Kobayashi, T, Hirakawa, K W, Moore, K, Yamada   +8 more
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Interleukin-10 and interleukin-10 receptor in human osteoarthritic and healthy chondrocytes.

Clinical and experimental rheumatology, 2001
To evaluate the expression of interleukin-10 (IL-10) and interleukin-10 receptor (IL-10R) on chondrocytes from healthy, osteoarthritic, and foetal cartilage from human subjects.Articular cartilage was obtained from 12 patients with osteoarthritis (OA) undergoing surgical knee replacement.
Iannone, F, De Bari, C, Dell'Accio, F, Covelli, M, Cantatore, F P, Patella, V, Lo Bianco, G, Lapadula, G   +7 more
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Interleukin-10 and its receptor.

Therapeutic immunology, 1995
The cytokine interleukin-10 (IL-10) has several important activities on cells of the immune system. IL-10 profoundly suppresses activation of macrophages, inhibiting their ability to secrete cytokines and serve as accessory cells for stimulation of T cell and natural killer (NK) cell function.
A S, Ho, K W, Moore
openaire   +1 more source

Expression and possible role of interleukin-10 receptors in patients with adenomyosis

European Journal of Obstetrics & Gynecology and Reproductive Biology, 2012
To investigate the expression and potential roles of interleukin-10 receptor 1 (IL-10R1) and interleukin-10 receptor 2 (IL-10R2) in adenomyosis.This prospective study examined 33 women with histologically proven adenomyosis and 21 women without adenomyosis who had undergone hysterectomy for non-endometrial pathology.
Xiaoyan, Qin, Hualing, Zhang, Fei, Wang, Jing, Xue, Zeqing, Wen   +4 more
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Interleukin-10 and related cytokines and receptors.

Annual review of immunology, 2004
The Class 2 alpha-helical cytokines consist of interleukin-10 (IL-10), IL-19, IL-20, IL-22, IL-24 (Mda-7), and IL-26, interferons (IFN-alpha, -beta, -epsilon, -kappa, -omega, -delta, -tau, and -gamma) and interferon-like molecules (limitin, IL-28A, IL-28B, and IL-29). The interaction of these cytokines with their specific receptor molecules initiates a
Sidney, Pestka, Christopher D, Krause, Devanand, Sarkar, Mark R, Walter, Yufang, Shi, Paul B, Fisher   +5 more
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Molecular Biology of Interleukin-10 and its Receptor

1995
The cytokine interleukin-10 (IL-10) was initially described as cytokine synthesis inhibitory factor (CSIF), a product of mouse T helper 2 (Th2) clones which inhibited cytokine synthesis—and therefore the effector functions—of mouse T helper 1 (Thl) clones.1–3 IL-10 potently suppresses activation of macrophages, inhibiting release of monokines and the ...
Kevin W. Moore, Alice S.-Y. Ho, Jiangchun Xu-Amano   +2 more
openaire   +1 more source

Proteasome-Mediated Proteolysis of the Interleukin-10 Receptor Is Important for Signal Downregulation

Journal of Interferon & Cytokine Research, 2006
The cytokine interleukin-10 (IL-10) is an important regulator of immune cell function, proliferation, and survival. The IL-10 receptor (IL-10R) consists of two subunits, IL-10R1 and IL-10R2, both belonging to the class II cytokine receptor superfamily.
Sherry H-Y, Wei, Andrew, Ming-Lum, Ying, Liu, David, Wallach, Christopher J, Ong, Stephen W, Chung, Kevin W, Moore, Alice L-F, Mui   +7 more
openaire   +2 more sources