Results 251 to 260 of about 10,848,813 (305)

Neural-immune-cardiovascular axis: from mechanistic crosstalk to therapeutic targets in cardiovascular disease. [PDF]

Front Immunol
Cheng J, Gao S, Zhang H, Gao W, Mei Z, Liu X, Gao J, Guo C, An G.   +8 more
europepmc   +1 more source

Stress Hyperglycemia Drives CD4+ T Cell PANoptosis and Postoperative Organ Injury via Monocyte‐Derived Succinate

Advanced Science, EarlyView.
High glucose is linked to reduced succinate dehydrogenase activity in CD14+ monocytes, accompanied by succinate accumulation and extracellular release. Extracellular succinate exacerbates mitochondrial ROS production and mtDNA release in CD4+ T cells. Cytosolic mtDNA then activates Z‐DNA binding protein 1 (ZBP1) and engages ZBP1‐associated inflammatory
Shuai Zhao, Xuemei Miao, Wei Luo, Tao Liu, Yang Wang, Jiaying Li, Di Fu, Weiyun Shen, Yan Luo, Kang Chen, Ruping Dai, Hui Li   +11 more
wiley   +1 more source

Regulatory effects and mechanisms of the acupuncture-induced complement component 1q on the high mobility group box 1 -receptor for advanced glycation end products-nuclear factor kappa-B pathway at Zusanli (ST36). [PDF]

J Tradit Chin Med
Xiaochun K, Sinuo WU, Ningcen LI, Wenyue XU, Zhifang XU, Yikchih T, Peiyun LI, Shiwei TU, Ning MA, Yanwei LI, Baomin D, Wenjun T, Jing G, Yi G, Xingfang P, Zhongxi L.   +15 more
europepmc   +1 more source

A vicious cycle of microglial dysfunction: bridging synaptic pruning and neuroinflammation across the neurodevelopmental continuum. [PDF]

Front Immunol
Yang F, Tang Q, Wang X, Chen J, Li Y, Liu W, Ma B, Shi W.   +7 more
europepmc   +1 more source

Immunoregulatory mechanisms in parasitic eosinophilic lung disease: the role of IgE immune complexes and NLRC4 inflammasome. [PDF]

Front Immunol
Cao Y, Rao D, Peng Z, Chen Z, Xia Q, Xie C, Fu Y, Huang D, Zhang Z, Yao C.   +9 more
europepmc   +1 more source

Integrated transcriptomic and immune-associated network analysis of breast cancer patient-derived organoids reveals candidate inflammatory biomarkers. [PDF]

Front Bioeng Biotechnol
Scippa S, Balestrieri A, Zanfardino M, Salvatore M, Soricelli A, D'aiuto M, Mossetti G, Ciaramella V.   +7 more
europepmc   +1 more source

Impact of Aggregatibacter actinomycetemcomitans on inflammasome regulation and epigenetic changes in grade C periodontitis. [PDF]

Clin Oral Investig
Reis AA, Paz HES, Sacramento CM, Silvério KG, Sallum EA, Freitas Monteiro M, Casarin RCV, Stolf CS.   +7 more
europepmc   +1 more source

Estradiol-17β, a key embryonic signal, regulates gene expression and cellular functions in the porcine trophoblast. [PDF]

Biol Reprod
Goryszewska-Szczurek E, Waclawik A.
europepmc   +1 more source

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Interleukin-10 and the Interleukin-10 Receptor

Annual Review of Immunology, 2001
Interleukin-10 (IL-10), first recognized for its ability to inhibit activation and effector function of T cells, monocytes, and macrophages, is a multifunctional cytokine with diverse effects on most hemopoietic cell types. The principal routine function of IL-10 appears to be to limit and ultimately terminate inflammatory responses.
K W, Moore, R, de Waal Malefyt, R L, Coffman, A, O'Garra   +3 more
openaire   +2 more sources