Results 251 to 260 of about 81,009,517 (308)

STING/Type I Interferon Pathway Activation Confers Multimodal Therapeutic Benefits in Osteomyelitis

Advanced Science, EarlyView.
STING/type I interferon signaling counteracts osteomyelitis through coordinated control of pain, bone destruction, and abscess formation. It inhibits pathogen‐induced nociceptor activation, restrains osteoclast‐mediated bone resorption, and suppresses IL‐1β‐driven neutrophil recruitment.
Yang Chen, Jianhua Lv, Yuanqing Cai, Xuhui Yuan, Hongxin Hu, Jiayu Li, Yiming Lin, Hongyan Li, Lan Lin, Huangfeng Lin, Chaofan Zhang, Qijin Wang, Ying Huang, Zida Huang, Wenbo Li, Susheng Niu, Jianhua Lin, Bin Yang, Xinyu Fang, Wenming Zhang   +19 more
wiley   +1 more source

Neural Expression of IL-16 Mediates Neuropathic Pain after Sciatic Injury in Mice. [PDF]

Mol Neurobiol
Coro-Martín A, Álvarez-Artime A, González-Rodríguez S, González-Amor M, Corral-Fontecha D, Baamonde A, Menéndez L.   +6 more
europepmc   +1 more source

Effects of phytocannabinoids, synthetic and semi-synthetic cannabinoids on microglia and astrocytes: Review of neuroinflammatory mechanisms. [PDF]

J Neuropathol Exp Neurol
Brambilla G, Belli G, Paggi A, Morini L, Visonà SD.   +4 more
europepmc   +1 more source

Aripiprazole modulates splenic microbiota and immune response elicited by single prolonged stress in rats. [PDF]

Pharmacol Rep
Vargovic P, Tillinger A, Horvathova L, Dziewiczova L, Osacka J.   +4 more
europepmc   +1 more source

Systemic immune-inflammatory disturbance and multiorgan dysfunction in patients with sepsis-associated acute-on-chronic liver failure. [PDF]

Am J Transl Res
Liu J, Jiang L, Liu Y, Chang Y.
europepmc   +1 more source

Targeting the IL-23 pathway in inflammatory bowel disease: from cytokine inhibition to oral IL-23 receptor blockade. [PDF]

eGastroenterology
Honap S, Colwill M, Dignass A, Jairath V, Magro F, Danese S, Peyrin-Biroulet L.   +6 more
europepmc   +1 more source

Functional Heterogeneity of Immune Cell Subpopulations in Atherosclerosis: From Basic Mechanisms to Precision Therapy. [PDF]

Rev Cardiovasc Med
Li M, Bian C, Li B.
europepmc   +1 more source