Results 271 to 280 of about 10,848,813 (305)
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Molecular Biology of Interleukin-10 and its Receptor
1995The cytokine interleukin-10 (IL-10) was initially described as cytokine synthesis inhibitory factor (CSIF), a product of mouse T helper 2 (Th2) clones which inhibited cytokine synthesis—and therefore the effector functions—of mouse T helper 1 (Thl) clones.1–3 IL-10 potently suppresses activation of macrophages, inhibiting release of monokines and the ...
Kevin W. Moore +2 more
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Expression and possible role of interleukin-10 receptors in patients with adenomyosis
European Journal of Obstetrics & Gynecology and Reproductive Biology, 2012To investigate the expression and potential roles of interleukin-10 receptor 1 (IL-10R1) and interleukin-10 receptor 2 (IL-10R2) in adenomyosis.This prospective study examined 33 women with histologically proven adenomyosis and 21 women without adenomyosis who had undergone hysterectomy for non-endometrial pathology.
Xiaoyan, Qin +4 more
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Interleukin-10 and related cytokines and receptors.
Annual review of immunology, 2004The Class 2 alpha-helical cytokines consist of interleukin-10 (IL-10), IL-19, IL-20, IL-22, IL-24 (Mda-7), and IL-26, interferons (IFN-alpha, -beta, -epsilon, -kappa, -omega, -delta, -tau, and -gamma) and interferon-like molecules (limitin, IL-28A, IL-28B, and IL-29). The interaction of these cytokines with their specific receptor molecules initiates a
Sidney, Pestka +5 more
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Journal of Interferon & Cytokine Research, 2006
The cytokine interleukin-10 (IL-10) is an important regulator of immune cell function, proliferation, and survival. The IL-10 receptor (IL-10R) consists of two subunits, IL-10R1 and IL-10R2, both belonging to the class II cytokine receptor superfamily.
Sherry H-Y, Wei +7 more
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The cytokine interleukin-10 (IL-10) is an important regulator of immune cell function, proliferation, and survival. The IL-10 receptor (IL-10R) consists of two subunits, IL-10R1 and IL-10R2, both belonging to the class II cytokine receptor superfamily.
Sherry H-Y, Wei +7 more
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Homozygosity of the interleukin‐10 receptor 1 G330R allele is associated with schizophrenia
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2006AbstractInfections of unknown origin and an altered immune response have been hypothesized to play a role in the pathogenesis of schizophrenia. We have previously identified two single nucleotide polymorphisms (SNPs) of the IL‐10 receptor 1 (IL‐10R1) causing a substitution of glycine 330 to arginine (G330R) and of serine 138 to glycine (S138G).
Schosser, Alexandra +10 more
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Interleukin-10 receptor blockade enhances neuroinflammation in Theiler’s murine encephalomyelitis
201560th Annual Meeting of the German Society for Neuropathology and Neuroanatomy (DGNN)
Uhde, AK +6 more
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Membrane-Bound Receptors of the Interleukin-10 Family of Cytokines
Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 2006The interleukin-10 (IL-10) family of cytokines includes IL-10, its viral homologs, and eight cellular cytokines: IL-19, IL-20, IL-22, IL-24, IL-26, IFN-λ1, IFN-λ2, and IFN-λ3. Cellular homologs use for signaling five recently discovered membrane-bound receptors: three long receptor chains (IL-20R1, IL-22R1, and IFN-λR) and two short receptor chains
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Interleukin-6 Signaling and Anti-Interleukin-6 Therapeutics in Cardiovascular Disease
Circulation Research, 2021exaly
Biology and therapeutic potential of interleukin-10
Journal of Experimental Medicine, 2020Anne O'Garra +2 more
exaly