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Treatment-Free Remission in Chronic Myeloid Leukemia: Toward Precision and Personalized Approaches to Functional Cure. [PDF]

Cancer Sci
Ureshino H, Kimura S.
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[Interleukin 13 and interleukin 13 receptor involvement in systemic sclerosis].

La Revue de medecine interne, 2007
Interleukin 13 is an immunoregulatory cytokine predominantly secreted by activated Th2 cells. It has similar functions with interleukin 4 and they share a common receptor. However, unlike interleukin 4, l'interleukin 13 does not appear to be important in the initial differentiation of CD4 T into Th2-type cells, but rather appears to be necessary in the
Granel, B., Chevillard, C., Dessein, A.
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Interleukin‐13 and interleukin‐13 receptor in Hodgkin's disease: possible autocrine mechanism and involvement in fibrosis

Histopathology, 2001
Aims: Hodgkin's disease (HD) is characterized by the presence of Hodgkin and Reed–Sternberg (H–RS) cells against a hyperplastic background of reactive cells such as lymphocytes, histiocytes, plasma cells, eosinophils, neutrophils, and stromal cells.
K, Ohshima, M, Akaiwa, R, Umeshita, J, Suzumiya, K, Izuhara, M, Kikuchi   +5 more
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Characterization of the mouse interleukin-13 receptor α1 gene

Immunogenetics, 2000
Interleukin (IL)-13 is a pleiotropic immune regulatory cytokine that shares structural and biological characteristics with IL-4. The receptor for IL-13 is comprised of the IL-4 receptor alpha (IL-4Ralpha) subunit and a low-affinity IL-13-binding subunit, IL-13Ralpha1.
M, Osawa, S, Miyoshi, N G, Copeland, D J, Gilbert, N A, Jenkins, T, Hiroyama, T, Motohashi, Y, Nakamura, A, Iwama, H, Nakauchi   +9 more
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Identification of serum interleukin‐13 and interleukin‐13 receptor subunit expressions: Rheumatoid arthritis–associated interstitial lung disease

International Journal of Rheumatic Diseases, 2021
AbstractAim of the workTo identify the role of serum IL‐13, and its receptor subunit expressions as a serologic marker of rheumatoid arthritis (RA)‐associated ILD (RA‐ILD).Patients and MethodsFifty RA patients with ILD and 50 RA patients without ILD were examined, in addition to 50 controls.
Manal Shawky Hussein, Amal Mohamad El‐Barbary, Doaa Waseem Nada, Rasha Ahmad Gaber, Reham Mohamed Elkolaly, Marwa Ahmed Aboelhawa   +5 more
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Interleukin 13 and interleukin 13 receptor are frequently expressed by Hodgkin and Reed-Sternberg cells of Hodgkin lymphoma

Blood, 2001
Hodgkin lymphoma (HL) is characterized by the abnormal expression of multiple cytokines, accounting for its unique clinicopathologic features. We have previously shown that interleukin-13 (IL-13) is secreted by HL cell lines and may serve as an autocrine growth factor. To determine the frequency of IL-13 expression in lymphoma patients, tissue sections
B F, Skinnider, A J, Elia, R D, Gascoyne, L H, Trümper, F, von Bonin, U, Kapp, B, Patterson, B E, Snow, T W, Mak   +8 more
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Expression of a Restrictive Receptor for Interleukin 13 is Associated with Glial Transformation

Journal of Neuro-Oncology, 2000
We have previously documented that the vast majority of high-grade gliomas over-express binding sites for interleukin 13 (IL13) in situ. We now extend this analysis to evaluate the distribution of the binding of IL13 among other brain tumors. Tumor specimens from patients with low-grade gliomas, oligodendrogliomas, ependymomas, pilocytic astrocytomas ...
W, Debinski, B, Slagle, D M, Gibo, S K, Powers, G Y, Gillespie   +4 more
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Interleukin-13 receptor as a unique target for anti-glioblastoma therapy

International Journal of Cancer, 2001
Surgery, radiotherapy and chemotherapy have minimally altered survival of glioblastoma patients. We explored a specific approach for glioblastoma therapy in which cellular interleukin-13 (IL-13) receptors were targeted by an IL-13 cytotoxin. A wide array of human glioblastoma cell lines expressing the receptor for IL-13 were effectively killed by an IL-
S R, Husain, B H, Joshi, R K, Puri
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Expression of interleukin-4 and interleukin-13 and their receptors in colorectal cancer

International Journal of Colorectal Disease, 2012
Interleukin-4 (IL-4) and interleukin-13 (IL-13) are anti-inflammatory and immunomodulatory cytokines which can influence cancer-directed immunosurveillance. Nothing is presently known about expression of these cytokines and their receptors (IL-4R and IL-13R) in colorectal cancer.
Andrea, Formentini, Philipp, Braun, Harald, Fricke, Karl-Heinrich, Link, Doris, Henne-Bruns, Marko, Kornmann   +5 more
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