Results 281 to 290 of about 446,523 (309)

Enhanced Expression of Interleukin-18 Receptor α Chain by CD4+ T Cells in Sarcoidosis

Chest, 2005
To investigate the expression of interleukin-18 receptor alpha chain (IL-18Ralpha) in BAL and peripheral blood (PB) T cells in patients with sarcoidosis compared with control subjects, to evaluate the relationship between the expression and clinical manifestations, and to clarify the mechanisms of altered expression.The study subjects consisted of 21 ...
Yanqiu, Zhou, Etsuro, Yamaguchi, Yoshinobu, Fukui, Satoshi, Konno, Yukiko, Maeda, Koji, Kimata, Masaharu, Nishimura   +6 more
openaire   +2 more sources

Epstein-Barr virus nuclear antigen 2 induces interleukin-18 receptor expression in B cells

Blood, 2005
Epstein-Barr virus (EBV) latently infects and immortalizes B lymphocytes and causes lymphoproliferative malignancies. We show here that the EBV nuclear antigen EBNA2 induces expression of the 2 chains of the interleukin-18 receptor (IL-18R) in Burkitt lymphoma (BL) cell lines and in nontransformed B cells.
Franck, Pagès, Jérôme, Galon, Galina, Karaschuk, Diana, Dudziak, Mathieu, Camus, Vladimir, Lazar, Sophie, Camilleri-Broët, Christine, Lagorce-Pagès, Sophie, Lebel-Binay, Gerhard, Laux, Wolf-Herman, Fridman, Berthold, Henglein   +11 more
openaire   +2 more sources

[Expression of interleukin-18 and interleukin-18 receptor alpha chain of the peripheral white blood cells in immune thrombocytopenia].

Zhonghua nei ke za zhi, 2010
To detect the expression of interleukin (IL)-18 of the peripheral blood cells and IL-18 receptor alpha chain (IL-18Ralpha) on the surface of CD(3)(+) cells in patients newly diagnosed as immune thrombocytopenia (ITP) before medication and to explore the roles of IL-18 and IL-18Ralpha in the development of ITP.Eighteen out-patients or inpatients with ...
Qian, Wang, Feng-xia, Zhan, Ning-ning, Shan, Ming, Hou, Xiao-jing, Yang, Nan, Lu, Hong-chun, Wang, Xiao-lin, Zhang, Xue-bin, Ji, Chun-yan, Ji   +9 more
openaire   +1 more source

[The role of interleukin-18 and interleukin-18 receptor in predominant Th1 immune response of patients with immune thrombocytopenia].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi, 2011
To evaluate the role of interleukin (IL)-18 and IL-18 receptor (IL-18R) in the predominant Th1 type cytokine response in patients with immune thrombocytopenia (ITP).Fifteen patients with active phase ITP, eighteen in remission and thirteen healthy controls were enrolled in this study. T-bet and GATA-3 mRNA levels in peripheral blood mononucleated cells
Qian, Wang, Xiao-Jing, Yang, Ning-Ning, Shan, Ming, Hou, Xue-Bin, Ji, Chun-Yan, Wang, Xiao-Juan, Zhu, Lei, Yang, Xiao-Lin, Zhang, Jun, Peng, Dao-Xin, Ma, Yan, Shi   +11 more
openaire   +1 more source

Localization of interleukin-18 and its receptor in somatotrophs of the bovine anterior pituitary gland

Cell and Tissue Research, 2005
A pro-inflammatory cytokine, interleukin 18 (IL-18), induces intracellular expression of IL-1 and the release of IL-6. IL-1 and IL-6 has been detected in anterior pituitary cells, suggesting that IL-18 is produced in anterior pituitary cells and may serve to aid immuno-endocrine regulation.
Yasuhiro, Nagai, Tomonori, Nochi, Kouichi, Watanabe, Keisuke, Watanabe, Hisashi, Aso, Haruki, Kitazawa, Masatoshi, Matsuzaki, Shyuichi, Ohwada, Takahiro, Yamaguchi   +8 more
openaire   +2 more sources

Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.

European cytokine network, 2000
Interleukin-18 (IL-18) mRNA is expressed in islets of NOD mice during the early stages of insulitis and IL-18 has therefore been implicated as a contributing factor in immune-mediated beta-cell destruction. However, a recent study failed to show any effect of human IL-18 on the function of isolated rat islets.
T P, Hong, N A, Andersen, K, Nielsen, A E, Karlsen, G, Fantuzzi, D L, Eizirik, C A, Dinarello, T, Mandrup-Poulsen   +7 more
openaire   +1 more source

Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity

Cancer Cell, 2022
Yared Hailemichael, Noha Abdel-Wahab, Wai C Foo   +2 more
exaly  

Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19

New England Journal of Medicine, 2021
Anthony C Gordon, Paul Mouncey, Farah Al-Beidh   +2 more
exaly  

Phase 3 Trial of Interleukin-1 Trap Rilonacept in Recurrent Pericarditis

New England Journal of Medicine, 2021
Allan L Klein, Massimo M Imazio, Antonio Luca Brucato   +2 more
exaly  

Interleukin 18 receptor.

Journal of biological regulators and homeostatic agents, 2005
Sergi, B., Penttila, I.
openaire   +1 more source