Results 31 to 40 of about 113,043,833 (209)

Suppression of interleukin-1 beta and LDL scavenger receptor expression in macrophages by a selective protein kinase C inhibitor.

Journal of Lipid Research, 1991
A human monocytic cell line, THP-1, stimulated with 40 nM phorbol myristate acetate (PMA), differentiated to macrophage-like cells, and exhibited increased expression and release of interleukin-1 beta and expression of acetylated low density lipoprotein (
AL Akeson, K Schroeder, C Woods, CJ Schmidt, W D Jones   +4 more
doaj   +1 more source

The onset of labor alters corticotropin-releasing hormone type 1 receptor variant expression in human myometrium : putative role of interleukin-1ß [PDF]

, 2007
CRH targets the human myometrium during pregnancy. The efficiency of CRH actions is determined by expression of functional receptors (CRH-R), which are dynamically regulated.
Gu, Mei, Grammatopoulos, Dimitris, Markovic, Danijela, Slater, Donna, Newton, Rob, Vatish, Manu, Lehnert, Hendrik, Rob Newton, Danijela Markovic, Donna Slater, Hendrik Lehnert, Mei Gu, Dimitris K. Grammatopoulos, Manu Vatish   +13 more
core   +1 more source

Evidence for Monocyte Reprogramming in a Long-Term Postsepsis Study

Critical Care Explorations, 2022
OBJECTIVES:. This study sought to identify monocyte alterations from septic patients after hospital discharge by evaluating gene expression of inflammatory mediators and monocyte polarization markers.
Raquel Bragante Gritte, PhD, Talita Souza-Siqueira, PhD, Eliane Borges da Silva, PhD, Laiane Cristina dos Santos de Oliveira, PhD, Rodrigo Cerqueira Borges, PhD, Heloísa H de Oliveira Alves, PhD, Laureane Nunes Masi, PhD, Gilson Masahiro Murata, PhD, Renata Gorjão, PhD, Adriana Cristina Levada-Pires, PhD, Antônio Carlos Nogueira, PhD, Tânia Cristina Pithon-Curi, PhD, Ricardo Bentes de Azevedo, PhD, Francisco Garcia Soriano, MD, PhD, Rui Curi, PhD, Marcel Cerqueira Cesar Machado, MD, PhD   +15 more
doaj   +1 more source

Unsaturated fatty acids suppress interleukin-2 production and transferrin receptor expression by concanavalin A-stimulated rat Iymphocytes

Mediators of Inflammation, 1992
The proliferation of T-lymphocytes is dependent upon their ability to synthesize and secrete the cytokine, interleukin-2, and to express cell surface receptors for interleukin-2 and transferrin.
Philip C. Calder, Eric A. Newsholme
doaj   +1 more source

Alexithymia and interleukin variations in somatoform disorder [PDF]

, 2007
Objective: The aim of the present study was to investigate if somatoform disorders (SFD) are associated with changes in the normal serum levels of important interleukins, and further, to establish if these changes are related to the presence and severity
Schwarz, M.J., Ridout, Nathan, Schwarz, Markus J., Pedrosa Gil, F., Schoechlin, Claudia, Nickel, Marius, Schmidmaier, R., Gil, Francisco Pedrosa, Ridout, N., Schmidmaier, Ralf, Nickel, M., Schoechlin, C.   +11 more
core   +1 more source

Exploring causal associations between interleukins, their receptors, and acute respiratory distress syndrome: a bidirectional-Mendelian Randomization study

Frontiers in Genetics
BackgroundAcute Respiratory Distress Syndrome (ARDS) is a severe lung condition posing significant health risks. Observational studies have indicated a potential linkage between ARDS and various interleukins, such as Interleukin-8, −2, −6, and −1β ...
Jia-wei Ma, Jia-wei Ma, Ji-chun Tang, Hong-zhi Fang   +3 more
doaj   +1 more source

Interleukin-2 receptor and ovarian cancer [PDF]

British Journal of Cancer, 1993
Interleukin-2 receptor (IL-2R) can be detected in serum. We estimated the IL-2R in the serum of 78 women, of whom 30 were diagnosed as having malignant ovarian tumours, five had non ovarian tumours, one had a negative second look laparotomy, 11 had benign ovarian tumours, three had uterine fibroids and 28 were age-matched controls.
Owens, OJ, Taggart, C, Wilson, R, Walker, JJ, McKillop, JH, Kennedy, JH   +5 more
openaire   +3 more sources

Molecular Mechanisms of Depression: Perspectives on New Treatment Strategies

Cellular Physiology and Biochemistry, 2013
Depression is a multicausal disorder and has been associated with the risk to develop cancer, dementia, diabetes, epilepsy and stroke. As a metabolic disorder depression has been associated with obesity, diabetes, insulin sensitivity, neuropeptide Y ...
Undine E. Lang, Stefan Borgwardt
doaj   +1 more source

Effect of human breast milk on innate immune response: Up-regulation of bacterial pattern recognition receptors and innate cytokines in THP-1 monocytic cells

European Journal of Inflammation, 2021
Human breast milk (HBM) contains many bioactive components that protect infants from various microorganisms. Pattern recognition receptors on phagocytic cells recognize microbial pathogens and promote the innate immune system.
Won-Ho Hahn, Soon Young Shin, Jun Hwan Song, Nam Mi Kang   +3 more
doaj   +1 more source

Fibronectin III 13-14 Domains Induce Joint Damage via Toll-Like Receptor 4 Activation and Synergize with Interleukin-1 and Tumour Necrosis Factor [PDF]

, 2011
Cartilage loss is a feature of chronic arthritis. It results from degradation of the extracellular matrix which is composed predominantly of aggrecan and type II collagen.
Saralili Dipa Robertson, Sofat, N, Nidhi Sofat, Wait, R, Robertson, SD, Robin Wait   +5 more
core   +1 more source