Results 41 to 50 of about 113,043,833 (209)

Expression of the Toll-like receptors 2 gene as a genetic determinant of the formation of newborns multiple organ failure syndrome

The Turkish Journal of Pediatrics, 2019
Activation of the humoral immune response in newborns` multiple organ failure syndrome is associated with the production of interleukin-1β, which is recognized via Toll-like receptors 2 (TLR2).
Dmytro A Shkurupii
doaj   +1 more source

Expression of interleukin 2 receptors on activated human B cells. [PDF]

, 1984
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
J M Depper, Robb, RJ, Bongiovanni, KF, Leonard, WJ, Waldmann, TA, Sharrow, SO, C K Goldman, W J Leonard, Korsmeyer, SJ, Depper, JM, T A Waldmann, S O Sharrow, R J Robb, S J Korsmeyer, K F Bongiovanni, Greene, WC, W C Greene, Goldman, CK   +17 more
core   +1 more source

Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]

, 2003
Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda, Zsuzsa Gyorfy, Duda, Erno, Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Annette Ohnemus, Kaspers, Bernd, Gyorfy, Zsuzsa, Ohnemus, Annette, Bernd Kaspers   +10 more
core   +1 more source

The role of interleukin-4 receptor alpha on smooth muscle cells during helminth infection [PDF]

, 2011
Includes abstract.Includes bibliographical references (leaves 101-111).Interleukin-4 receptor alpha (IL-4Ra) signaling, mediated by the ligands IL-4 and IL- 13, is important for effective host protection during murine Nippostrongylus brasiliensis (N ...
Brombacher, Tiroyaone M H
core   +1 more source

Sympathetic Nervous System Catecholamines and Neuropeptide Y Neurotransmitters Are Upregulated in Human NAFLD and Modulate the Fibrogenic Function of Hepatic Stellate Cells [PDF]

, 2013
Background Sympathetic nervous system (SNS) signalling regulates murine hepatic fibrogenesis through effects on hepatic stellate cells (HSC), and obesity-related hypertension with SNS activation accelerates progression of non-alcoholic fatty liver ...
Vander Borght, S, McKee, C, Vander Borght Sara, Mazzoccoli, G, Ching-I Lin, Gianluigi Mazzoccoli, Lin Ching-I, Selden, C, Maelle Morgan, Pazienza Valerio, Selden Clare, Junpei Soeda, Jude A Oben, Barbara Sigala, Manlio Vinciguerra, Oben, JA, Tania Roskams, Sara Vander Borght, Pazienza, V, Roskams, T, Clare Selden, Lin, CI, McKee Chad, Mazzoccoli Gianluigi, Vinciguerra, M, Morgan Maelle, Valerio Pazienza, Sigala Barbara, Vinciguerra Manlio, Soeda, J, Chad McKee, Soeda Junpei, Oben Jude A., Sigala, B, Roskams Tania, Morgan, M, Lin, C   +36 more
core   +2 more sources

Th1/Th2 cytokine production and reception features in Graves' disease

Клиническая и экспериментальная тиреоидология, 2012
Cytokines and their receptors belong to a significant role in the initiation and the subsequent course and outcome of autoimmune thyroid disease. Interleukin-2 (IL-2), interleukin-4 (IL-4) and tumor necrosis factor-alpha (TNF-α)-cytokines, which have a ...

doaj   +1 more source

Interleukin-18 [PDF]

, 2003
Interleukin-18 (IL-18), a recently described member of the IL-1 cytokine superfamily, is now recognized as an important regulator of innate and acquired immune responses.
McInnes, I.B., Robertson, S.E., Gracie, J.A.   +2 more
core   +1 more source

Blockade of 5-hydroxytryptamine (serotonin)-2 receptors alters interleukin-1-induced changes in rat sleep

, 1999
Recent data suggest that interleukin-1-induced enhancement of non-rapid eye movement sleep is mediated, in part, by the serotonergic system. To determine if sleep changes induced by interleukin-1 are mediated by a specific serotonergic receptor subtype ...
L. Imeri, M. Mancia, M. Opp, M.R Opp, M Mancia, L Imeri   +5 more
core   +1 more source

Induction of interleukin 2 responsiveness in thymocytes by synergistic action of interleukin 1 and interleukin 2 [PDF]

, 1985
Thymocyte cultures from C3H/HeJ mice were stimulated for proliferative responses with purified preparations of interleukin 1 (IL 1) and interleukin 2 (IL 2). Synergistic responses were obtained in the absence of mitogen.
Falk, Werner, Mizel, S. B., Diamantstein, T., Männel, D. N.   +3 more
core   +1 more source

Synergy between sphingosine 1-phosphate and lipopolysaccharide signaling promotes an inflammatory, angiogenic and osteogenic response in human aortic valve interstitial cells.

PLoS ONE, 2014
Given that the bioactive lipid sphingosine 1-phosphate is involved in cardiovascular pathophysiology, and since lipid accumulation and inflammation are hallmarks of calcific aortic stenosis, the role of sphingosine 1-phosphate on the pro-inflammatory/pro-
Isabel Fernández-Pisonero, Javier López, Esther Onecha, Ana I Dueñas, Patricia Maeso, Mariano Sánchez Crespo, José Alberto San Román, Carmen García-Rodríguez   +7 more
doaj   +1 more source