Results 61 to 70 of about 113,043,833 (209)

Full-length and N-terminally truncated interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 receptors

open access: yes
Source data linked to the manuscript 'Full-length and N-terminally truncated interleukin-38 variants are similarly inefficient in antagonizing interleukin-36 and interleukin-1 ...
Palmer-Lourenco, Gaby   +2 more
core   +1 more source

Signaling Pathways Activated by Interleukin-2 and Interluekin-4 Receptors Mediate T Lymphocyte Clonal Expansion [PDF]

open access: yes, 2007
Cells sense and respond to chemical and physical stimuli through signal transduction pathways, which mediate cell proliferation, differentiation, migration, and survival.
Comfort, Kristen K.
core   +1 more source

Dupilumab: Basic aspects and applications to allergic diseases

open access: yesAllergology International, 2020
Interleukin (IL)-4 and IL-13, signature type 2 cytokines, exert their actions by binding to two types of receptors sharing the IL-4R α chain (IL-4Rα).
Kazuto Matsunaga   +4 more
doaj   +1 more source

The effects of blockade of interleukin 2 receptors and interleukin 4 receptors on cytokine production

open access: yes, 1991
The understanding of the regulation of cytokine production and T-cell proliferation by other cytokines is far from complete. We have examined the supernatant concentration of different cytokines in cultured peripheral blood lymphocytes (PBL) incubated ...
Lai, KN   +4 more
core   +1 more source

In vivo manipulation of interleukin-2 expression by a retroviral tetracycline (tet)-regulated system [PDF]

open access: yes, 2006
We have used the tetracycline (tet)-regulated system as described previously to evaluate the applicability of controlled gene expression in cancer gene therapy. As a model gene, we used the human interleukin-2 (IL-2) gene, which has been placed under the
Wirth, Thomas   +4 more
core   +1 more source

TRAF Regulation of IL-17 Cytokine Signaling

open access: yesFrontiers in Immunology, 2019
Tumor necrosis factor receptor (TNFR)-associated factors or (TRAFs) are important mediators of Interleukin-17 (IL-17) cytokine signaling and contribute to driving tissue responses that are crucial for protective immunity but are often implicated in ...
Shadi Swaidani   +5 more
doaj   +1 more source

Interleukin 2 Regulates its own Receptors. [PDF]

open access: yes, 1985
The cell surface density of high-affinity membrane receptors for the T-lymphocytotrophic hormone interleukin 2 (IL-2) determines the rate of T-cell-cycle progression.
Cantrell, D. A.   +3 more
core   +1 more source

Regulation and functions of interleukin-2 receptors on normal and HTLV-I-infected human T lymphocytes

open access: yes, 1990
Interleukin-2 is a T cell derived lymphokine which plays a central role in immune responses. This dissertation examines three issues relating to in vitro regulation and function of interleukin-2 receptors on normal human T lymphocytes and cells infected ...
Margolin, David Harris
core  

Soluble interleukin‐6 receptor in young adults and its relationship with body composition and autonomic nervous system

open access: yesPhysiological Reports, 2019
Background The immune system generates inflammatory responses through cytokines like Interleukin 6 (IL‐6) and the Tumor Necrosis Factor alpha (TNF α); these cytokines mediate cellular responses aided by the presence of soluble receptors such as: Soluble ...
Henry H. León‐Ariza   +3 more
doaj   +1 more source

Genetic modification and effector functions of natural killer cells in acute myeloid leukemia [PDF]

open access: yes, 2006
Acute myeloid leukemia (AML) is characterized by a poor long-term outcome in the majority of patients following conventional treatment with chemotherapy.
Siegler, Uwe
core   +1 more source

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