Results 271 to 280 of about 511,016 (309)
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APMIS, 1991
The understanding of the regulation of cytokine production and T‐cell proliferation by other cytokines is far from complete. We have examined the supernatant concentration of different cytokines in cultured peripheral blood lymphocytes (PBL) incubated with monoclonal antibodies against the interleukin‐2 receptor (IL‐2R) or interleukin‐4 receptor (IL‐4R)
Lai, KN +4 more
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The understanding of the regulation of cytokine production and T‐cell proliferation by other cytokines is far from complete. We have examined the supernatant concentration of different cytokines in cultured peripheral blood lymphocytes (PBL) incubated with monoclonal antibodies against the interleukin‐2 receptor (IL‐2R) or interleukin‐4 receptor (IL‐4R)
Lai, KN +4 more
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Involvement of gp130/interleukin‐6 receptor transducing component in interleukin‐11 receptor
European Journal of Immunology, 1994AbstractThe recently cloned interleukin (IL)‐11 displays many biological properties in common with those reported for IL‐6. In order to analyze the nature and the functionality of the IL‐11 receptor we developed a proliferative assay using the human multifactor‐dependent cell line TF1.
M, Fourcin +6 more
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Interleukin-3 and its receptor
1995Cytokines are actively involved in the host-defense system to coordinate the functional activity and the generation of effector cells. Some of these molecules function as inflammatory mediators and hematopoietic growth factors at the same time such as IL-1, IL-6, IL-3, IL-5, and GM-CSF.
Lindemann, Albrecht, Mertelsmann, Roland
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Interleukin‐3 and Interleukin‐3 Receptors in the Braina
Annals of the New York Academy of Sciences, 1998We have previously demonstrated that interleukin 3 (IL‐3) has a neurotrophic effect on central cholinergic neurons and have demonstrated the presence of IL‐3 receptor (IL‐3R)β subunits in septal cholinergic neurons by reverse‐transcribed polymerase chain reaction (RT‐PCR) and immunohistochemistry.
T, Tabira +4 more
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Interleukin-1 Receptor Antagonist
1993IL-1ra is the first described naturally occurring receptor antagonist of any cytokine or hormone-like molecule. IL-1ra is a member of the IL-1 family by three criteria: amino acid sequence homology of 26 to 30% to IL-1 beta and 19% to IL-1 alpha; similarities in gene structure; and common gene localization to human chromosome 2q14.
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Regulation of Interleukin 2 Receptor Expression by Interleukin 2
Scandinavian Journal of Immunology, 1986The regulatory influence of Interleukin 2 (IL‐2) on the expression of IL‐2 receptors (IL.‐2R) was studied using long‐term cultured T‐cell lines and recombinant IL‐2 (r‐IL‐2). Three T‐cell lines with different growth requirements were used as model systems: insulin‐specific BK‐BI‐1.2 cells express IL‐2R transiently after antigenic restimulation ...
A B, Reske-Kunz +3 more
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Enhancing Interleukin-6 and Interleukin-11 receptor cleavage
The International Journal of Biochemistry & Cell Biology, 2017Proteolytic cleavage of the membrane-bound Interleukin-6 receptor (IL-6R) by the metalloprotease ADAM17 releases an agonistic soluble form of the IL-6R (sIL-6R), which is responsible for the pro-inflammatory trans-signaling branch of the cytokine's activities.
Juliane, Lokau +2 more
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Blocking interleukin-1 receptors
International Journal of Clinical & Laboratory Research, 1994During inflammation, injury, immunological challenge or infection, interleukin-1 appears to mediate, in part, the pathogenesis, of disease. Most studies on interleukin-1 are derived from experiments in which bacterial products, such as endotoxins from Gram-negative bacteria or exotoxins from Gram-positive organisms, are used to stimulate macrophagic ...
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The interleukin-1/interleukin-1-receptor interaction
Annales de l'Institut Pasteur / Immunologie, 1987H R, MacDonald, J W, Lowenthal
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The Multisubunit Interleukin‐2 Receptor
Annals of the New York Academy of Sciences, 1990W J, Leonard, J R, Gnarra, M, Sharon
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