Results 71 to 80 of about 1,112,126 (259)

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Role of interleukin-8 in neutrophil signaling

, 2000
Interleukin-8 was originally discovered as one of the first chemokines activating neutrophil granulocytes (neutrophils) after secretion by lipopolysaccharide-stimulated monocytes.
Zeilhofer, Hanns Ulrich; https://orcid.org/, Schorr, W   +1 more
core   +1 more source

Soluble Interleukin-2 Receptors in Patients with Advanced Colorectal Carcinoma

The International Journal of Biological Markers, 1996
The levels of soluble interleukin-2 receptors (sIL-2R) were measured in the serum of 52 patients with advanced colorectal carcinoma and compared to CEA and CA 19-9 levels. Twenty-five normal, age and sex-matched individuals served as controls.
N. Pavlidis, C. Nicolaides, E. Bairaktari, J. Kalef-Ezra, A. Athanassiadis, C. Seferiadis, G. Fountzilas   +6 more
doaj   +1 more source

Atopic march in pediatrics: genotype-associated mechanisms Part 1. Genotype-associated mechanisms of the atopic march in children

Zdorovʹe Rebenka, 2017
The review deals with the data of studies over last 10 years of populations of different countries on association of atopic diseases being the components of the atopic march in children (atopic eczema, allergic rhinitis, allergic rhinoconjunctivitis ...
V.O. Dytiatkovsky
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Serum soluble interleukin-2 receptors in epithelial ovarian cancer patients

The International Journal of Biological Markers, 1995
The levels of soluble interleukin-2 receptors (sIL-R2) were measured in the serum of 52 patients with epithelial ovarian carcinoma as well as in 25 age and sex-matched normal controls.
N.A. Pavlidis, E. Bairaktari, J. Kalef-Ezra, C. Nicolaides, C. Seferiadis, G. Fountzilas   +5 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Interleukin-1 beta induces long-term increase of axonally transported opiate receptors and substance P.

, 1995
Interleukin-1 is known to exert pleiotropic effects in host defence mechanisms and in inflammation. Chronic pain, inflammation and interleukin-1 beta enhance the production of substance P.
Maloteaux, Jean-Marie, Moussaoui, S M, Laduron, P M, Jeanjean, Anne, P.M. Laduron, S.M. Moussaoui, J.-M. Maloteaux, A.P. Jeanjean   +7 more
core   +1 more source

Comparison of Serum TNF-Α, Interleukin-10, Interferon Gamma and Interleukin-12 Levels in Mycobacterium Tuberculosis and Non-Tuberculosis Patients

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2010
Introduction: Determination of produced cytokines, especially interleukin 10, interleukin 12, interferon gamma and TNF-α is an important tool in the review of safety responses against inducers such as illnesses.
A Velayati, M Masjedi, M Bayat, M Kazempoor, P Farnia, K Taghavi, S Anooshe   +6 more
doaj  

The Inflammasome in Host Defense

Sensors, 2009
Nod-like receptors have emerged as an important family of sensors in host defense. These receptors are expressed in macrophages, dendritic cells and monocytes and play an important role in microbial immunity. Some Nod-like receptors form the inflammasome,
Gang Chen, Joao H.F. Pedra
doaj   +1 more source