Results 91 to 100 of about 53,696 (166)

Microbiome affects mice metabolic homeostasis via differential regulation of gene expression in the brain and gut

Physiological Reports
The gut microbiome (GMB) regulates digestion, metabolism, immunity, and energy homeostasis. This study investigates how gut microbiota integrate the regulation in the neuroendocrine and enteroendocrine systems, with a focus on G protein‐coupled receptors
Wynne Milhouse, Anna Clapp Organski, Xun Sun, Derek Ai, Baohua Zhou, Tzu‐Wen L. Cross, Hongxia Ren   +6 more
doaj   +1 more source

Endothelial cell leptin receptors, leptin and interleukin-8 in the pathogenesis of preeclampsia: An in-vitro study. [PDF]

Turk J Obstet Gynecol, 2017
Arlıer S.
europepmc   +1 more source

LEPTIN RECEPTORS IN CAVEOLAE: REGULATION OF LIPOLYSIS IN 3T3-L1 ADIPOCYTES

, 2004
The present study has tested the hypothesis that leptin receptors are localized in caveolae and that caveolae are involved in the leptin-induced stimulation of lipolysis in 3T3-L1 adipocytes. Leptin, a peptide hormone, is secreted primarily by adipocytes
Chikani, Gentle P.
core  

Photoperiod Affects Gene Expression of Leptin and Leptin Receptors in Adipose Tissue from Lactating Dairy Cows

, 2006
Leptin is mainly secreted by adipocytes and is implicated in the regulation of metabolic status, feed intake, and body condition. Day length (DL) can affect leptin gene expression and secretion.
Morera P., Bernabucci U., Basificò L., Nardone A., ACCORSI, PIER ATTILIO, Lacetera N., Ronchi B., SEREN, ERALDO   +7 more
core  

Hypothalamic obesity. [PDF]

Rev Endocr Metab Disord
Farooqi IS, O'Rahilly S.
europepmc   +1 more source

Neuroendocrine and neural control of bone mass in health and disease. [PDF]

J Clin Invest
Zaidi M, Kim SM, Ryu V, Lizneva D, Davies TF, Rosen CJ, Yuen T, Giustina A.   +7 more
europepmc   +1 more source

G Protein-Coupled Receptor 17 (Gpr17) Enhances Leptin and Insulin Sensitivity in Lean and Obese Mouse Models. [PDF]

Obesity (Silver Spring)
Sun X, Mahler C, Stull ND, Nasiri A, Zhou B, Samuel V, Shulman G, Flak JN, Ren H.   +8 more
europepmc   +1 more source

Fetal pancreatic islets express functional leptin receptors and leptin stimulates proliferation of fetal islet cells

, 2000
OBJECTIVE: Previous studies have demonstrated that leptin can stimulate proliferation of insulin-secreting tumor cell lines. The objective of this study was to characterize whether leptin could stimulate proliferation of primary beta-cells too.
Islam, M. Shahidul,, Emilsson, V., Sjöholm, Å.   +2 more
core  

Hypothalamic regulation of sepsis-associated anorexia: cytokine and hormonal signalling through AgRP/POMC circuits. [PDF]

EMBO Mol Med
Zhu W, Libert C, Vanderhaeghen T.
europepmc   +1 more source

The role of leptin in the central nervous system remyelination

, 2019
Leptin is identified as a mouse obesity gene, which is also preserved in humans. Leptin receptor is highly expressed in the hypothalamus relative to other tissues; therefore, the function of leptin is mainly attributed to hypothalamic control of food ...
Ken Matoba, Rieko Muramatsu, Toshihide Yamashita
core