Results 71 to 80 of about 632,116 (307)
INSULIN AND LEPTIN: DISPUTABLE AND UNSOLVED QUESTIONS OF THEIR INTERACTION
Атеросклероз, 2019 Leptin and its receptor are widely distributed mainly in white adipose tissue. Serum leptin concentration correlates with body mass index, and its levels decrease with fasting.
E. V. Belik +2 more
doaj +1 more source
Leptin in the Respiratory Tract: Is There a Role in SARS-CoV-2 Infection?
Frontiers in Physiology, 2021 Leptin is a pleiotropic adipocytokine involved in several physiologic functions, with a known role in innate and adaptive immunity as well as in tissue homeostasis.
Andreina Bruno +4 more
doaj +1 more source
The Antidiabetic Potential of Alpha‐Mangostin: A Review of Preclinical and Clinical Evidence
AgriFood: Journal of Agricultural Products for Food, EarlyView.Alpha‐mangostin is a compound from the pericarp of Garcinia mangostana. The antidiabetic effects of alpha‐mangostin include enhancing insulin secretion, improving glucose uptake through GLUT receptor upregulation, reducing oxidative stress and inflammation, promoting wound healing, reducing HbA1C, reducing HOMA‐IR index, and decreased mRNA expressions ...
Oliver Dean John +4 more
wiley +1 more source
Metabolic syndrome, the leptin gene and kidney disease in non-diabetic black South Africans [PDF]
, 2008 Includes abstract.Includes bibliographical references (leaves 226-256).Obesity is a worldwide problem and is a factor in the pathogenesis of the metabolic syndrome and kidney disease through the development of obesity-related hypertension and ...
Okpechi, Ikechi Gareth
core +1 more source
, 2010 In a rat model of intrauterine growth restriction (IUGR) induced by maternal global undernutrition, adult offspring are obese with associated metabolic disturbances. These metabolic abnormalities are all augmented by feeding a high calorie postnatal diet
Garratt, Emma
core +1 more source
Mediators of Inflammation, 2019 Leptin resistance is either a condition induced by human obesity or a natural phenomenon associated with seasonality in ruminants. In the cardiovascular system, the leptin resistance state presence is a complex issue.
Agata Krawczyńska +5 more
doaj +1 more source
The melanocortin receptors and their accessory proteins. [PDF]
, 2013 The five melanocortin receptors (MCRs) named MC1R-MC5R have diverse physiological roles encompassing pigmentation, steroidogenesis, energy homeostasis and feeding behavior as well as exocrine function.
Adrian J. L. Clark +12 more
core +1 more source
Automating AI Discovery for Biomedicine Through Knowledge Graphs and Large Language Models Agents
Advanced Intelligent Discovery, EarlyView.This work proposes a novel framework that automates biomedical discovery by integrating knowledge graphs with multiagent large language models. A biologically aligned graph exploration strategy identifies hidden pathways between biomedical entities, and specialized agents use this pathway to iteratively design AI predictors and wet‐lab validation ...
Naafey Aamer +3 more
wiley +1 more source
The glucoregulatory actions of leptin
Molecular Metabolism, 2017 Background: The hormone leptin is an important regulator of metabolic homeostasis, able to inhibit food intake and increase energy expenditure. Leptin can also independently lower blood glucose levels, particularly in hyperglycemic models of leptin or ...
Anna M. D'souza +3 more
doaj +1 more source
The role of melanocortins and cytokines in human adipose tissue and adipocytes [PDF]
, 2007 During the last decades obesity has become a major health problem in developed countries, and more recently also in the developing countries it is seriously affecting parts of the populations.
Hoch, Matthias
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