Results 61 to 70 of about 53,696 (166)

Leptin and peroxisome proliferator activated receptor alpha: understanding their contribution towards normalising the programmed phenotype in the peripheral tissues of IUGR offspring

, 2010
In a rat model of intrauterine growth restriction (IUGR) induced by maternal global undernutrition, adult offspring are obese with associated metabolic disturbances. These metabolic abnormalities are all augmented by feeding a high calorie postnatal diet
Garratt, Emma
core  

Role of Leptin and metabolism in survival of autoreactive CD4+ T cells

, 2009
Recent evidence has shown that leptin, the adipose-tissue derived hormone, can influence T cell homeostasis and survival through the control of genes involved in these processes. Leptin deficient ob/ob mice and humans show reduced circulating number of T
Galgani, Mario
core  

Postnatal development of hypothalamic leptin receptors.

, 2010
The hormone, leptin, plays a key role in the regulation of energy balance and neuroendocrine function, as well as modulating a range of other physiological systems from immunity to cognition.
Cottrell, Elizabeth C.; id_orcid, Julian G. Mercer, Ozanne, Susan E., Susan E. Ozanne, Elizabeth C. Cottrell, Mercer, Julian G.   +5 more
core   +1 more source

Leptin receptors in human skeletal muscle [PDF]

, 2007
Human skeletalmuscle expresses leptin receptor mRNA; however, it remains un-known whether leptin receptors (OB-R) are also expressed at theprotein level.
Dorado, Cecilia, Fuentes, Teresa, Cabrera-Socorro, Alfredo, Delgado Guerra, Safira, Santana, Alfredo, Calbet, Jose A. L., Guerra, Borja, Fuentes Nieto, Teresa, Delgado Guerra,Safira, Cabrera Socorro, Alfredo   +9 more
core   +1 more source

Expression of leptin and leptin receptors in gestational trophoblastic diseases

, 2004
To investigate the expression profile of leptin and leptin receptors in gestational trophoblastic diseases (GTDs). Using immunohistochemical staining on archival paraffin-embedded tissue sections, we studied the expression of leptin and leptin receptor ...
Li, HWR, Li, RHW, Yu, MMY, Cheung, ANY, Wong, YF   +4 more
core   +1 more source

Melanocortins and agouti-related protein modulate the excitability of two arcuate nucleus neuron populations by alteration of resting potassium conductances [PDF]

, 2007
The hypothalamic melanocortin system is crucial for the control of appetite and body weight. Two of the five melanocortin receptors, MC3R and MC4R are involved in hypothalamic control of energy homeostasis, with the MC4R having the major influence. It is
Hisadome, Kazunari, Michael L. J. Ashford, Smith, Mark A., Helen Heffron, Mark A. Smith, Al-Qassab, Hind, Kazunari Hisadome, Withers, Dominic J., Hind Al‐Qassab, Dominic J. Withers, Ashford, Michael L. J.; id_orcid, Heffron, Helen   +11 more
core   +1 more source

Estimation of Leptin and Leptin Receptor Concentrations in Seminal Plasma of Primary Infertile Men

مجلة كلية الطب, 2017
Background: There are many sources for Leptin secretion, and it is activated by binding with its receptor known as leptin receptor, that play a role in male infertility.
Ruqaya M. AL-Barzinji, Ahmed A. AL-Naqshbandi   +1 more
doaj   +1 more source

Leptin receptor expression during the progression of endometrial carcinoma is correlated with estrogen and progesterone receptors

, 2016
Introduction : The hormone leptin, which is produced in the adipose tissue, may influence tumorigenesis directly via its receptor (Ob-R). Thus, a role for Ob-R in endometrial carcinogenesis has been proposed.
Luis Fernando Méndez-López, Ricardo M. Cerda-Flores, Angel Zavala-Pompa, Elva I. Cortés-Gutiérrez, Martha I. Davila-Rodriguez   +4 more
core   +1 more source

Control of food intake via leptin receptors in the hypothalamus

, 2000
Food intake is regulated via neural circuits located in the hypothalamus. During the past decade our knowledge on the specific mediators and neuronal networks that regulate food intake and body weight has increased dramatically. An important contribution
Björn Meister, Meister, B,
core   +1 more source

New Frontiers in Gut Nutrient Sensor Research: Nutrient Sensors in the Gastrointestinal Tract: Modulation of Sweet Taste Sensitivity by Leptin

Journal of Pharmacological Sciences, 2010
The ability to perceive sweet compounds is important for animals to detect an external carbohydrate source of calories and has a critical role in the nutritional status of animals.
Nao Horio, Masafumi Jyotaki, Ryusuke Yoshida, Keisuke Sanematsu, Noriatsu Shigemura, Yuzo Ninomiya   +5 more
doaj   +1 more source