Results 41 to 50 of about 53,696 (166)

Intrathecal Leptin Inhibits Expression of the P2X Receptors and Alleviates Neuropathic Pain Induced by Chronic Constriction Sciatic Nerve Injury

Molecular Pain, 2013
Background Leptin, an adipocytokine produced mainly by white adipose tissue, has a broad role in the regulation of neuronal functions. Accumulating evidence has revealed that leptin plays an important role in influencing neuropathic pain, shown recently ...
Xin Li, Lumei Kang, Guilin Li, Huihong Zeng, Lei Zhang, Xiang Ling, Hui Dong, Shangdong Liang, Hongping Chen   +8 more
doaj   +1 more source

Effects of diabetes family history and exercise training on the expression of adiponectin and leptin and their receptors [PDF]

, 2011
Daughters of diabetes patients have lower insulin sensitivity than women with no diabetes family history, but increase insulin sensitivity to a greater extent with exercise training.
Moran, Colin N., Barwell, Nicholas D., Packard, Chris J, Packard, C.J., McPhee, Ian, Packard, Christopher J., Zammit, Victor A, Gill, J. M. R. (Jason M. R.), Cleland, S., Gill, J.M.R., Moran, C.N., Barwell, Nicholas D, Malkova, D., Barwell, N.D., Gill, Jason M R, Cleland, Steve J., Zammit, Victor A., McPhee, I., Moran, Colin Neil, Cleland, Stephen J, Zammit, V.A., Malkova, Dalia   +21 more
core   +1 more source

Insulin and Leptin Signaling Interact in the Mouse Kiss1 Neuron during the Peripubertal Period. [PDF]

PLoS ONE, 2015
Reproduction requires adequate energy stores for parents and offspring to survive. Kiss1 neurons, which are essential for fertility, have the potential to serve as the central sensors of metabolic factors that signal to the reproductive axis the presence
Xiaoliang Qiu, Hoangha Dao, Mengjie Wang, Amelia Heston, Kaitlyn M Garcia, Alisha Sangal, Abigail R Dowling, Latrice D Faulkner, Scott C Molitor, Carol F Elias, Jennifer W Hill   +10 more
doaj   +1 more source

Leptin potentiates astrogenesis in the developing hypothalamus

Molecular Metabolism, 2015
Background: The proper establishment of hypothalamic feeding circuits during early development has a profound influence on energy homeostasis, and perturbing this process could predispose individuals to obesity and its associated consequences later in ...
Daniele M. Rottkamp, Ivan A. Rudenko, Matthew T. Maier, Sahar Roshanbin, Ernie Yulyaningsih, Luz Perez, Martin Valdearcos, Streamson Chua, Suneil K. Koliwad, Allison W. Xu   +9 more
doaj   +1 more source

The role of leptin in selected skin diseases

Lipids in Health and Disease, 2020
Leptin is an adipokine, adipocyte-derived compound, which acts both as a hormone and cytokine. It is mainly synthesized by adipocytes of white adipose tissue. Leptin possesses pleiotropic functions including, among others, stimulation of angiogenesis and
Klaudia Dopytalska, Agnieszka Baranowska-Bik, Marek Roszkiewicz, Wojciech Bik, Irena Walecka   +4 more
doaj   +1 more source

Plasma Leptin Levels, Polymorphism and Mammographic Breast Density: A Cross-sectional Study

The International Journal of Biological Markers, 2013
Obesity is associated with breast cancer in postmenopausal women, and breast density is a marker of breast cancer risk. Leptin is produced by the adipose tissue, acts through receptors that are polymorphic in nature, and is considered a cancer growth ...
Cher Dallal, Seymour Garte, Camille Ragin, Jiangying Chen, Stacy Lloyd, Francesmary Modugno, Joel Weissfeld, Emanuela Taioli   +7 more
doaj   +1 more source

Leptin in the Respiratory Tract: Is There a Role in SARS-CoV-2 Infection?

Frontiers in Physiology, 2021
Leptin is a pleiotropic adipocytokine involved in several physiologic functions, with a known role in innate and adaptive immunity as well as in tissue homeostasis.
Andreina Bruno, Giuliana Ferrante, Serena Di Vincenzo, Elisabetta Pace, Stefania La Grutta   +4 more
doaj   +1 more source

INSULIN AND LEPTIN: DISPUTABLE AND UNSOLVED QUESTIONS OF THEIR INTERACTION

Атеросклероз, 2019
Leptin and its receptor are widely distributed mainly in white adipose tissue. Serum leptin concentration correlates with body mass index, and its levels decrease with fasting.
E. V. Belik, O. V. Gruzdeva, E. I. Palicheva   +2 more
doaj   +1 more source

Relationships between cord blood leptin and ghrelin levels, milk intake and weight gain in human infants [PDF]

, 2003
Leptin and ghrelin are hormones involved in the regulation of appetite and adiposity. Leptin suppresses appetite and induces weight loss; ghrelin stimulates appetite and promotes weight gain.
James, Rachel J. A., James, Rachel J A
core  

The Influence of Photoperiod on the Action of Exogenous Leptin on Gene Expression of Proinflammatory Cytokines and Their Receptors in the Thoracic Perivascular Adipose Tissue (PVAT) in Ewes

Mediators of Inflammation, 2019
Leptin resistance is either a condition induced by human obesity or a natural phenomenon associated with seasonality in ruminants. In the cardiovascular system, the leptin resistance state presence is a complex issue.
Agata Krawczyńska, Andrzej P. Herman, Hanna Antushevich, Joanna Bochenek, Karolina Wojtulewicz, Dorota A. Zięba   +5 more
doaj   +1 more source