Results 41 to 50 of about 632,116 (307)

Differences in zinc status and the leptin axis in anorexic and recovered adolescents and young adults : a pilot study [PDF]

, 2012
Background: Evidence from animal studies suggests that leptin metabolism is associated with zinc (Zn) status. However, research investigating this relationship in adolescents and young adults with anorexia nervosa (AN) is scarce; the present study aims ...
Wöckel, Lars, Hintereder, Gudrun, F. Glass, Kratzsch, J., Wöckel, L., Sungurtekin, I., I. Sungurtekin, Sungurtekin, Idil, F.D. Zepf, Biskup, Caroline, Zepf, Florian Daniel, Kratzsch, Jürgen, L. Wöckel, Peetz, D., Elstrodt, L., Biskup, Caroline Sarah, Hintereder, G., Poustka, F., D. Peetz, Peetz, Dirk, C.S. Biskup, Glass, F., J. Kratzsch, Zepf, F. D., G. Hintereder, Biskup, C. S., Elstrodt, Linda, Glass, Franziska, F. Poustka, Zepf, FD, Poustka, Fritz, L. Elstrodt   +31 more
core   +1 more source

Circulating TREM2 as a noninvasive diagnostic biomarker for NASH in patients with elevated liver stiffness

Hepatology, EarlyView., 2022
Abstract Background and Aims Reliable noninvasive biomarkers are an unmet clinical need for the diagnosis of NASH. This study investigates the diagnostic accuracy of the circulating triggering receptor expressed on myeloid cells 2 (plasma TREM2) as a biomarker for NASH in patients with NAFLD and elevated liver stiffness.
Vineesh Indira Chandran, Charlotte Wilhelmina Wernberg, Mette Munk Lauridsen, Maria Kløjgaard Skytthe, Sofie Marchsteiner Bendixen, Frederik Tibert Larsen, Camilla Dalby Hansen, Lea Ladegaard Grønkjær, Majken Storm Siersbæk, Tina Di Caterino, Sönke Detlefsen, Holger Jon Møller, Lars Grøntved, Kim Ravnskjaer, Søren Kragh Moestrup, Maja Sofie Thiele, Aleksander Krag, Jonas Heilskov Graversen   +17 more
wiley   +1 more source

Serum leptin and its relation to anthropometric measures of obesity in pre-diabetic Saudis [PDF]

, 2007
Background: Little information is available on leptin concentrations in individuals with IGT. This study aims to determine and correlate leptin levels to anthropometric measures of obesity in prediabetic, (IFG and IGT), type 2 diabetic and normoglycaemic
Al-Rubeaan, Khalid, Mohammad Al-Katari, Khalid Al-Rubeaan, Mohieldin, Mehad, Jones, Alan F., Kumar Sudhesh, Jones Alan F, Kumar, Sudhesh, Mehad Mohieldin, Al-Katari Mohammad, Al-Rubeaan Khalid, Mohieldin Mehad, Nasser M Al-Daghri, Sudhesh Kumar, Omar S Al-Attas, Al-Attas, Omar S., Alan F Jones, Al-Daghri, Nasser M., Al-Katari, Mohammad, Al-Attas Omar S, Al-Daghri Nasser M   +20 more
core   +1 more source

AIF1+CSF1R+ MSCs, induced by TNF‐α, act to generate an inflammatory microenvironment and promote hepatocarcinogenesis

Hepatology, EarlyView., 2022
Mesenchymal stem cells subset, educated by TNF‐α, are involved to generate inflammatory microenvironment and promote hepatocarcinogenesis Abstract Background and Aims Increasing evidence suggests that mesenchymal stem cells (MSCs) home to injured local tissues and the tumor microenvironment in the liver.
Chen Zong, Yan Meng, Fei Ye, Xue Yang, Rong Li, Jinghua Jiang, Qiudong Zhao, Lu Gao, Zhipeng Han, Lixin Wei   +9 more
wiley   +1 more source

Assessment of leptin and resistin levels in non-obese multiple myeloma patients and their relation with Ig level and disease stage

Journal of the Egyptian National Cancer Institute, 2014
Introduction: Multiple myeloma (MM) accounts for approximately 0.8% of all cancer diagnoses and 0.9% of cancer deaths. Leptin receptors were expressed on CD34+ cells.
Noha E. Esheba, Abeer Shahba, Ola El Shora   +2 more
doaj   +1 more source

Leptin receptor in boar spermatozoa [PDF]

International Journal of Andrology, 2007
SummaryLeptin is active in both metabolism and reproduction. In fact, it seems to exert an inhibitory action on gonadal functions by reducing testosterone production. The presence of leptin in human and boar seminal plasma and in human spermatozoa has been demonstrated; recently, leptin receptors (Ob‐R) have been localized in human spermatozoa, thus ...
DE AMBROGI, MARCO, SPINACI, MARCELLA, GALEATI, GIOVANNA, TAMANINI, CARLO   +3 more
openaire   +2 more sources

CORRELATION OF LEPTIN AND ADIPONECTIN RECEPTOR EXPRESSION WITH CLINICOPATHOLOGICAL PARAMETERS IN COLORECTAL CARCINOMA - A CROSS-SECTIONAL PROSPECTIVE STUDY [PDF]

Arquivos de Gastroenterologia
Background: Colorectal carcinoma (CRC) is one of the common carcinomas with a rising incidence of metastasis due to its advanced stage of presentation.
Priyanka PARMESH, Udupi Shastri DINESH, Ajay S KHANDAGALE, Anil Bargale BAPU, Roshni SADASHIV, Pradnya REDDY   +5 more
doaj   +1 more source

Leptin and leptin receptor evaluation in atherosclerotic plaques in patients with type 2 diabetes mellitus

Терапевтический архив, 2021
Background. Diabetes mellitus (DM) is a significant predictor of atherosclerosis, cardiovascular disease, and cardiovascular mortality. It is known that atherosclerosis occurs earlier in patients with diabetes, reducing the duration of their life. Leptin
Diana A. Dimitrova, Ilya A. Mikhailov, Konstantin Yu. Tokarev, Marina S. Michurova, Anna M. Gorbacheva, Natalia V. Danilova, Pavel G. Malkov, Viktor Yu. Kalashnikov   +7 more
doaj   +1 more source

Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells

Molecular Metabolism, 2015
Aims/hypothesis: The adipose tissue-derived hormone leptin plays an important role in the maintenance of body weight and glucose homeostasis. Leptin mediates its effects by interaction with leptin receptors (LepRb), which are highly expressed in the ...
Helen Soedling, David J. Hodson, Alice E. Adrianssens, Fiona M. Gribble, Frank Reimann, Stefan Trapp, Guy A. Rutter   +6 more
doaj   +1 more source

Leptin and Notch Signaling Cooperate in Sustaining Glioblastoma Multiforme Progression

Biomolecules, 2020
Glioblastoma multiforme (GBM) is the most malignant form of glioma, which represents one of the commonly occurring tumors of the central nervous system.
Salvatore Panza, Umberto Russo, Francesca Giordano, Antonella Leggio, Ines Barone, Daniela Bonofiglio, Luca Gelsomino, Rocco Malivindi, Francesca Luisa Conforti, Giuseppina Daniela Naimo, Cinzia Giordano, Stefania Catalano, Sebastiano Andò   +12 more
doaj   +1 more source