Results 131 to 140 of about 2,265,539 (159)

The prolonged action of the LHRH agonist buserelin (HOE 766) may be due to prolonged binding to the LHRH receptor

Life Sciences, 1986
Hemi-pituitary glands of ovariectomized rats were superfused for 4 h with either LHRH or the analog buserelin (HOE 766) at several concentrations, and thereafter with medium only for another 1.5 h. In a further experiment glands were exposed for 2.5 h to LHRH or buserelin at a single concentration (5 ng/ml) and subsequently for another 2.5 h to either ...
T. R. Koiter, Maria Andries, Henk Moes, Gerard A. Schuiling, Carl Denef   +4 more
openaire   +4 more sources

Opiate receptors modulate LHRH and SRIF release from mediobasal hypothalamic neurons.

Neuroendocrinology, 1981
In order to investigate the effect of opiates on luteinizing hormone-releasing hormone (LHRH) and somatostatin (SRIF) release, mediobasal hypothalamic (MBH) slices of male adult rats were superfused ...
S. Drouva, J. Epelbaum, L. Tapia‐Arancibia, E. Laplante, C. Kordon   +4 more
semanticscholar   +1 more source

Modulation of prolactin, luteinizing hormone (LH) and follicle stimulating hormone (FSH) secretion by LHRH and bromocriptine (CB154) in the hypophysectomized pituitary-grafted male rat and its effect on testicular LH receptors and testosterone output.

Biology of Reproduction, 1979
lypophysectomized adult male rats with a pituitary transplant under the kidney capsule were used to study the effects of chronic treatment with LHRH, with or without CB154, on the secre- tion of LH, FSH and prolactin and the action of these hormones on ...
A. McNeilly, D. D. de Kretser, R. Sharpe
semanticscholar   +1 more source

Evidence for LHRH-Receptor Expression in Human Airway Epithelial (Calu-3) Cells and Its Role in the Transport of an LHRH Agonist [PDF]

Pharmaceutical Research, 2004
To determine whether LHRH-receptor is expressed in Calu-3, a human bronchial epithelial cell line, and to further determine whether this receptor plays a role in the transport of deslorelin, an LHRH agonist.Using cultured monolayers of Calu-3 grown at air-interface, the presence and localization of LHRH-receptors in Calu-3 cells was determined using ...
Kavitha Koushik, Nagesh Bandi, Sneha Sundaram, Uday B. Kompella   +3 more
openaire   +2 more sources

Solubilization of a large molecular weight form of the rat LHRH receptor

Journal of Endocrinology, 1987
ABSTRACT The LHRH receptor has been solubilized from male rat anterior pituitary glands, using the zwitterionic detergent 3-((3-cholamidopropyl)-dimethylammonio)-1-propanesulphonate in the presence of a high concentration of sodium chloride. This method gave high yields (up to > 70%) of the LHRH-binding site from the membrane preparation ...
Rory Mitchell, George Fink, Sally-Ann Ogier   +2 more
openaire   +3 more sources

Maternal modulation of infantile ovarian development and available ovarian luteinizing hormone-releasing hormone (LHRH) receptors via milk LHRH.

Endocrinology, 1984
In the rat, ovarian LHRH receptor content, measured by the binding of [125I]D-Ala6-Pro9-LHRH ([125I]A-LHRH) to ovarian membranes, declines during the days preceding the first preovulatory LH surge.
Sheryl S. Smith, S. Ojeda
semanticscholar   +1 more source

Ovarian LHRH receptors increase following lesions of the major LHRH structures in the rat brain: involvement of a direct neural pathway.

Neuroendocrinology, 1985
Specific lesions of different brain structures known to contain or to be coursed by LHRH neurons have been carried out in intact cycling female rats in order to investigate the role played by central LHRH and neuronal systems in the regulation of ovarian
B. Marchetti, M. Cioni, U. Scapagnini
semanticscholar   +1 more source

Peripubertal Decline in Ovarian LHRH Receptor Content: Characterization and Distribution

Neuroendocrinology, 1983
In the rat, ovarian LHRH receptor content, as measured by the binding of 125I-D-Ala6, Pro9-LHRH (A-LHRH) to ovarian membranes, decreases markedly during the days preceding the first preovulatory gonadotropin surge. The present study shows that the decrease in LHRH receptor number occurs exclusively in granulosa cells, and that the greatest rate of ...
Sheryl Smith White, Sergio Ojeda
openaire   +3 more sources

Specific, estrogen-sensitive alterations in anterior pituitary cytoplasmic and nuclear estrogen receptors actuated by LHRH.

Neuroendocrinology, 1983
We have previously demonstrated that LHRH is capable of eliciting a dramatic and direct elevation of anterior pituitary levels of nuclear estrogen receptors (E2R) [18, 24].
P. Singh, T. G. Muldoon
semanticscholar   +1 more source

Pituitary LHRH receptors during puberty in the female rat: is the proestrous decline in receptor content due to occupancy?

Endocrinology, 1982
As during the adult estrous cycle, the number of pituitary luteinizing hormone-releasing hormone (LHRH) receptors was found to increase prior to the first preovulatory surge of LH.
S. S. White, S. Ojeda
semanticscholar   +1 more source