Results 141 to 150 of about 2,265,539 (159)
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Preparation and use of biotinylated ligands for LHRH receptor purification
Tetrahedron Letters, 1989Abstract The synthesis of biotinylated analogues of LHRH is described in which the peptides simultaneously combine biotin and either a photolabile or an amino substituent. In rat anterior pituitary membranes the conjugate [biotinyl-aminoethylglycyl-D-Lys 6 , des Gly 10 ]-LHRH ethylamide showed approximately 50% specific binding and could be ...
Christine M. Bladon +2 more
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D1 receptor mechanisms in the median eminence and their inhibitory regulation of LHRH release
Neurochemistry International, 1988D1 receptor mechanisms in the median eminence have been studied by means of immunocytochemistry using antisera against dopamine and cyclic AMP-regulated phosphoprotein-32 (DARPP-32) and tyrosine hydroxylase (TH) and by autoradiography using the iodinated analogue of the D1 receptor antagonist SCH-23390.
Fuxe K +7 more
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The Journal of experimental zoology, 1994
The effects of serotonin (5-hydroxytryptamine; 5-HT) alone, and in combination with luteinizing hormone-releasing hormone analog (LHRHa), on plasma levels of maturational gonadotropin (GtH II) in the post-vitellogenic female and spermiating male Atlantic
I. Khan, P. Thomas
semanticscholar +1 more source
The effects of serotonin (5-hydroxytryptamine; 5-HT) alone, and in combination with luteinizing hormone-releasing hormone analog (LHRHa), on plasma levels of maturational gonadotropin (GtH II) in the post-vitellogenic female and spermiating male Atlantic
I. Khan, P. Thomas
semanticscholar +1 more source
Allopregnanolone induces LHRH and glutamate release through NMDA receptor modulation
Endocrine, 2011LHRH release from hypothalamus is influenced by the neurotransmitter glutamate that acts, among others, on NMDA receptors present in LHRH neurons. On the other hand, the neurosteroid allopregnanolone can modulate the activity of specific neurotransmitter receptors and affect neurotransmitter release. We examined the role of allopregnanolone on in vitro
Claudia E. Mohn +6 more
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Pharmacological regulation of pituitary LHRH receptors
1984The tonic and pulsatile release of pituitary gonadotropic hormones is regulated by LHRH (Fink, 1976). In physiological circumstances, the secretion of LHRH is pulsatile rather than continuous. There is increasing evidence that modulation of pulse frequency, rather than the pulse amplitude, plays a critical role in the regulation of gonadotropin ...
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The regulation of LHRH action at the pituitary and gonadal receptor level: A review
Psychoneuroendocrinology, 1983Luteinizing hormone releasing-hormone (LHRH) and its highly active agonists are under clinical investigation for the control of reproductive function and for suppression of hormone dependent tumours. The regulation of LHRH action by pituitary receptors and expression of the biological LHRH effect by gonadotropin release and activation of steroid ...
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LHRH-receptor-regulated Ca2+-ATPase activity in murine pituitary gland
Neurochemical Research, 1987Addition of luteinizing hormone releasing hormone (LHRH) in vitro (10(-5) -5 X 10(-9) M) to murine pituitary membranes resulted in a dose-related decrease in Ca2+-ATPase activity within 15 min. Inhibitory effects of LHRH (10(-7) M) occurred after 90 sec, and appeared maximal by 120 sec.
S. A. Bernard +2 more
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Investigation of LHRH Receptor Involvement in Melanoma Growth and Progression
2003The hypothalamic decapeptide luteinizing hormone-releasing hormone (LHRH) is the prime controller of reproductive function (Fink, 1988). It performs this function, after being secreted from the hypothalamus into the hypophysial portal circulation, by binding and activating specific receptors on gonadotrophs (Stojilkovic et al, 1994).
Marina Montagnani Marelli +2 more
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A direct effect of LHRH on anterior pituitary estrogen receptors in the female rat
Journal of Steroid Biochemistry, 1982Abstract An analysis has been made of the effects of LHRH on anterior pituitary estrogen receptors. Dispersed pituitary cells from ovariectomized, estrogen-primed rats were incubated in the presence or absence of 1–10 ng of LHRH per pituitary equivalent for 30 min at 37°C.
Pomila Singh, Thomas G. Muldoon
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