Results 161 to 170 of about 8,988 (194)
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Pharmacological regulation of pituitary LHRH receptors
1984The tonic and pulsatile release of pituitary gonadotropic hormones is regulated by LHRH (Fink, 1976). In physiological circumstances, the secretion of LHRH is pulsatile rather than continuous. There is increasing evidence that modulation of pulse frequency, rather than the pulse amplitude, plays a critical role in the regulation of gonadotropin ...
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Opiate Receptors Modulate LHRH and SRIF Release from Mediobasal Hypothalamic Neurons
Neuroendocrinology, 1981In order to investigate the effect of opiates on luteinizing hormone-releasing hormone (LHRH) and somatostatin (SRIF) release, mediobasal hypothalamic (MBH) slices of male adult rats were superfused ...
S V, Drouva +4 more
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Endocrinology, 1984
In the rat, ovarian LHRH receptor content, measured by the binding of [125I]D-Ala6-Pro9-LHRH ([125I]A-LHRH) to ovarian membranes, declines during the days preceding the first preovulatory LH surge. The present results show that LHRH receptor content is low during neonatal-infantile days (days 5-15) and increases markedly thereafter to a maximum by day ...
S S, Smith, S R, Ojeda
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In the rat, ovarian LHRH receptor content, measured by the binding of [125I]D-Ala6-Pro9-LHRH ([125I]A-LHRH) to ovarian membranes, declines during the days preceding the first preovulatory LH surge. The present results show that LHRH receptor content is low during neonatal-infantile days (days 5-15) and increases markedly thereafter to a maximum by day ...
S S, Smith, S R, Ojeda
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BJU International, 2013
Luteinizing hormone‐releasing hormone ( LHRH ) agonists and antagonists are commonly used androgen deprivation therapies prescribed for patients with advanced prostate cancer ( PCa ). Both types of agent target the receptor for LHRH
Yuri, Tolkach +2 more
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Luteinizing hormone‐releasing hormone ( LHRH ) agonists and antagonists are commonly used androgen deprivation therapies prescribed for patients with advanced prostate cancer ( PCa ). Both types of agent target the receptor for LHRH
Yuri, Tolkach +2 more
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Neuroendocrinology, 1985
Specific lesions of different brain structures known to contain or to be coursed by LHRH neurons have been carried out in intact cycling female rats in order to investigate the role played by central LHRH and neuronal systems in the regulation of ovarian and hypophyseal LHRH receptor (LHRH-R) levels, using the stable LHRH analog [D-Ser (TBU)6] Des ...
MARCHETTI, Bianca Maria +2 more
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Specific lesions of different brain structures known to contain or to be coursed by LHRH neurons have been carried out in intact cycling female rats in order to investigate the role played by central LHRH and neuronal systems in the regulation of ovarian and hypophyseal LHRH receptor (LHRH-R) levels, using the stable LHRH analog [D-Ser (TBU)6] Des ...
MARCHETTI, Bianca Maria +2 more
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Life Sciences, 1986
Hemi-pituitary glands of ovariectomized rats were superfused for 4 h with either LHRH or the analog buserelin (HOE 766) at several concentrations, and thereafter with medium only for another 1.5 h. In a further experiment glands were exposed for 2.5 h to LHRH or buserelin at a single concentration (5 ng/ml) and subsequently for another 2.5 h to either ...
Koiter, T. R. +4 more
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Hemi-pituitary glands of ovariectomized rats were superfused for 4 h with either LHRH or the analog buserelin (HOE 766) at several concentrations, and thereafter with medium only for another 1.5 h. In a further experiment glands were exposed for 2.5 h to LHRH or buserelin at a single concentration (5 ng/ml) and subsequently for another 2.5 h to either ...
Koiter, T. R. +4 more
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Bioconjugate Chemistry, 2008
Polyelectrolyte complex (PEC) micelles modified with cancer cell targeting moieties were prepared for intracellular delivery of vascular endothelial growth factor (VEGF) small interfering RNA (siRNA). A luteinizing hormone-releasing hormone (LHRH) peptide analogue was coupled as a cancer targeting ligand to the distal end of the poly(ethylene glycol ...
Kim, SH Kim, Sun Hwa +4 more
exaly +4 more sources
Polyelectrolyte complex (PEC) micelles modified with cancer cell targeting moieties were prepared for intracellular delivery of vascular endothelial growth factor (VEGF) small interfering RNA (siRNA). A luteinizing hormone-releasing hormone (LHRH) peptide analogue was coupled as a cancer targeting ligand to the distal end of the poly(ethylene glycol ...
Kim, SH Kim, Sun Hwa +4 more
exaly +4 more sources
Avian lhrh receptors: An study
Journal of Steroid Biochemistry, 1984Peter B. Connolly, P. Ian
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Abiraterone acetate/enzalutamide/LHRH receptor agonists
Reactions Weekly, 2023openaire +1 more source