Results 171 to 180 of about 23,013 (268)

Mitochondria and Aging: Redox Balance Modulation as a New Approach to the Development of Innovative Geroprotectors (Fundamental and Applied Aspects). [PDF]

Int J Mol Sci
Mironova E, Kvetnoy I, Balazovskaia S, Antonov V, Poyarkov S, Mazzoccoli G.   +5 more
europepmc   +1 more source

Artificial intelligence streamlines scientific discovery of drug–target interactions

British Journal of Pharmacology, Volume 183, Issue 8, Page 1673-1690, April 2026.
Abstract Drug discovery is a complicated process through which new therapeutics are identified to prevent and treat specific diseases. Identification of drug–target interactions (DTIs) stands as a pivotal aspect within the realm of drug discovery and development. The traditional process of drug discovery, especially identification of DTIs, is marked by
Yuxin Yang, Feixiong Cheng
wiley   +1 more source

The influence of two neurohormones on breast cancer: prolactin and melatonin. [PDF]

Rev Assoc Med Bras (1992)
Ferreira CDS, Carvalho KC, Ferreira IDS, Cavalcanti GS, Cipolla Neto J, Zambotti PEO, Baracat EC, Soares Junior JM.   +7 more
europepmc   +1 more source

Melatonin and the Dental Pulp: A Scoping Review

International Endodontic Journal, Volume 59, Issue 4, Page 590-613, April 2026.
ABSTRACT Background In general medicine, melatonin is known to enhance wound healing and promote stem cell differentiation. Its potential relevance in endodontics, however, remains underexplored. Objectives This scoping review aimed to systematically assess the available evidence on the effects of melatonin (a) on dental pulp tissue and (b) on human ...
Jasmin Schäfer, Konrad Kleszczynski, Edgar Schäfer   +2 more
wiley   +1 more source

Melatonin Suppresses NLRP3 Inflammasome Activation via SIRT1-Mediated ETS1 Deacetylation to Attenuate LPS-Induced Pyroptosis in Alveolar Epithelial Cells. [PDF]

J Inflamm Res
He F, Liu C, Yu Y, Wang Q, Li L, Chao X, Chen L, Yu C.   +7 more
europepmc   +1 more source

Imperatorin Mitigates Rosacea‐Like Inflammation by Modulating the Crosstalk Between JNK1 and STAT1

The FASEB Journal, Volume 40, Issue 5, 15 March 2026.
IMP treatment disrupts the interaction between JNK1 and STAT1, thereby attenuating STAT1 activity. This interference subsequently diminishes the phosphorylation and nuclear translocation of STAT1, which ultimately results in a reduced production of inflammatory cytokines and chemokines.
Xiaoxue Wang, Zexin Zhu
wiley   +1 more source

Sperm freezability is associated with melatonin receptor expression in the sperm plasma membrane of Saanen goat bucks <i>(Capra hircus</i>). [PDF]

Vet World
Cardenas-Padilla AJ, Medrano A.
europepmc   +1 more source

Exploring the role of exogenous salicylic acid in cereals resilience to water deficit stress: Advances and challenges

Agronomy Journal, Volume 118, Issue 2, March/April 2026.
Abstract Salicylic acid (SA) is an elicitor of abiotic stress tolerance in plants, but a comparative analysis of its effects across cereals remains under‐explored. This review article assesses the literature on the biological functioning of exogenous SA application (foliar‐ or root‐applied) in water‐stressed cereals.
Christos A. Damalas, Spyridon D. Koutroubas   +1 more
wiley   +1 more source

The DREAMS START intervention for sleep in dementia: Long‐term follow‐up of a randomized controlled trial

Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.
Abstract INTRODUCTION Sleep disturbances are common and distressing for people with dementia and their family caregivers, with limited treatment options. The DREAMS START (Dementia RElAted Manual for Sleep; STrAtegies for RelaTives) multi‐component intervention for sleep disturbance in people at home with dementia is clinically and cost‐effective at 8 ...
Penny Rapaport, Mariam O. Adeleke, Julie A. Barber, Lina Gonzalez, Rachael Hunter, Monica Manela, Sarah Amador, Sube Banerjee, Georgina Charlesworth, Chris Clarke, Colin A. Espie, Simon D. Kyle, Malgorzata Raczek, Zuzana Walker, Gill Livingston   +14 more
wiley   +1 more source